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Tag: "labs" at biology news

Wisconsin scientists grow critical nerve cells

...e exact recipe for motor neuron growth, Li foraged labs worldwide to obtain the growth factors and other natural chemicals needed to guide cells from one stage of motor neuron development to another. But once past a certain point, Li found that the cells kept veering off toward different cellular destinie...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...at microarrays experiments performed in different labs "have a high degree of reproducibility , as lon..., and the experimentalcorrelation between separate labs was only slightly lower thancorrelation of duplicated experiments within the same labs. “Thisstudy ...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...h receptor from activation.Recent studies by other labs had shown that a number of stages in theNotch cascade were subject to ubiquitination, in which proteins aretagged by a complex of ubiquitin proteins. This system is best knownfor its function in marking proteins for degradation by a wastedisposal uni...

Study finds more than one-third of human genome regulated by RNA

...alled siRNAs. RNAi hasalready transformed how many labs are investigating gene functions, andsiRNAs are being developed for clinical applications. Learning moreabout how microRNAs operate in human cells should help scientists tounderstand how best to exploit siRNAs for treating disease....

NYU researchers simulate molecular biological clock

...alled siRNAs. RNAi hasalready transformed how many labs are investigating gene functions, andsiRNAs are being developed for clinical applications. Learning moreabout how microRNAs operate in human cells should help scientists tounderstand how best to exploit siRNAs for treating disease....

U-M scientists find genes that control growth of common skin cancer

...esults areconsistent with previous work from other labs studying differentHh-associated tumors, “but we were very surprised to see that sometumor cells persisted after shutting down Gli2 expression,?saidDlugosz.In some of the regressed tumors Gli2 reactivation leads to resumptionof BCC tumor growth, sugge...

Open microfluidic and nanofluidic systems

The labs of the future will be "labs-on-a-chip", i.e., inte... computer chip. An essential prerequisite for such labs are appropriate microcompartments for the confinement of very small amounts of liquids and chemical ...

Nanogen Issued Patent for Electronic Microarray With Memory

...and treat disease. Research and clinical reference labs use the highly accurate and reliable NanoChip(R) Molecular Biology Workstation, NanoChip(R) Electronic Microarray and broad suite of analyte specific reagents to develop tests to detect infectious diseases, drug toxicity and mutations associated with...

Bird Brains Show How Trial and Error May Contribute to Learning

...ity." Other researchers in the Brainard and Doupe labs are following up to see if the male mating song can be permanently altered by LMAN stimulation and whether females prefer the stable or variable song version. ...

PCRM develops world's first cruelty-free insulin assay

... and competitively priced, researchers and medical labs will use it," said Barnard. "We have proven that if researchers are willing to make the effort, there are effective, humane alternatives to animal-based assays and other testing procedures--alternatives that could help save the lives of millions of p...

Use of PET can reduce, may eliminate more strenuous drug development trials with animals

...many as 12,000 academic and private animal imaging labs in the world and that more than 200 may do small animal PET routinely. Through small animal imaging research, Welch and his researchers gained more of an understanding about titanium anti-cancer drugs and new techniques for PET imaging with 45Ti, wh...

Different microarray systems more alike than previously thought

...rcially available Affymetrix microarrays, and five labs used either of two more flexible systems. The Hop...curs in some labs, my intuition was that different labs might obtain very different answers even when using the same platform," said Irizarry. "But we show ...

Sugar beet virus mutation requires Texas touch

...ush, professor and director of the plant pathology labs in Bushland and Amarillo. "We do all of our work in the greenhouse and laboratory," he said. "Here, we have to have an understanding of everything, from the crop growing in the field to the molecular aspects of the pathogen. That makes our program t...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

...ersion. Previous tissue culture studies by several labs around the world indicated that tinkering with the tail end prevented the protein from being flagged for degradation or activation. Instead of accumulating in mouse cells and halting cell division in the genetically engineered mice, the altered p53 p...

Team Invents Device For Weighing Individual Molecules

...am will likely collaborate with various proteomics labs for side-by-side comparisons of already known information on the mass of biological molecules with results obtained with the new method. Roukes announced the technology in Los Angeles on Wednesday, March 24, at a news conference during the annual Am...

Anthrax test, developed by army and CDC, receives FDA approval

... is a big first step in helping to provide the LRN labs with FDA cleared assays," said Judy Sheldon, a regulatory affairs microbiologist with the CDC's Bioterrorism Preparedness and Response Program. "The work done at USAMRIID and here at CDC provided a solid scientific basis for FDA to evaluate the assa...

'Mad cow' proteins successfully detected in blood

... is a big first step in helping to provide the LRN labs with FDA cleared assays," said Judy Sheldon, a regulatory affairs microbiologist with the CDC's Bioterrorism Preparedness and Response Program. "The work done at USAMRIID and here at CDC provided a solid scientific basis for FDA to evaluate the assa...

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

... use luminescent dyes to study cells, so pathology labs will have the equipment needed to monitor drug delivery. Brewer is giving her invited talk, "Applications of mixed-metal supramolecular complexes in the development of chemotherapeutic and photodynamic therapy agents" (INOR 219), at 9:15 a.m. Monday...

Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search

... use luminescent dyes to study cells, so pathology labs will have the equipment needed to monitor drug delivery. Brewer is giving her invited talk, "Applications of mixed-metal supramolecular complexes in the development of chemotherapeutic and photodynamic therapy agents" (INOR 219), at 9:15 a.m. Monday...

Fundamental discovery -- Bone fracture

...sor Paul K. Hansma, in collaboration with the UCSB labs of Professors Daniel E. Morse and Galen D. Stucky, the interdisciplinary group of scientists spent several years tracking down where the glue was located in bone, and how it worked. "Before this research, it was well known that the mechanical proper...

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