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Tag: "laboratory" at biology news

Man and mouse share genome structures

...ral fellowship who works in the Harvard University laboratory of HHMI investigator Stuart L. Schreiber. Other co-authors are from the Broad Institute of MIT and Harvard, and Affymetrix. Their findings are published in the January 28, 2005 issue of Cell. "Now that the human genome has been sequenced, it is vita...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...apacity and the need for the development of better laboratory tests for such studies. "When DNA repair capacity can be measured easily and quickly, the scientific community will be able to clearly understand the role of DNA repair capacity in the development of cancer and possibly to develop interventions to re...

Source of molecular triggers in cutaneous T cell lymphoma identified

...arch scientist in dermatology set up a physiologic laboratory system mimicking the tight relationship in vivo between CTCL cells and LC. The research team considered three broad categories of antigen as the source of the signal: the protein products of tumor viruses, of mutated genes, and of normal but usually ...

Priming embryonic stem cells to fulfill their promise

...te it with off-the-shelf chemicals andstandardized laboratory machinery. "We think other researchers couldeasily use this technique with any other tissue in mouse, or human, orany other species," said Bhatia.Scientists have identified about 100 proteins - including laminin,fibronectin, and several kinds of coll...

Growth in the sea comes down to a struggle for iron

... the data they collected and conducting additional laboratory experiments. UMaine scientists are planning to return to the Pacific in 2007, but they have a different destination in mind. Work by Japanese and Canadian researchers has already shown that the consequences of iron additions may vary from the easter...

Fox Chase Cancer Center scientists identify immune-system mutation

...s appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in Fox Chase's laboratory animal facility in 1997. Known as "helper deficient" or HD mice, they are proving to be useful for e...

Termites feed through good vibrations

... intelligence. CSIRO entomologist Theo Evans says laboratory experiments have found that termites use their ability to detect vibrations to determine which food source is most suitable. The termites can also detect how the vibrations are made. This ability could be likened to a form of sonar. Dr Evans says di...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...the stem cells when they are grown or derived from laboratory culturesthat contain animal sources of the non-hum...s done with human embryonic stemcells grown in the laboratory of Fred Gage, Ph.D., professor,Laboratory of Genetics, the Salk Institute, La Jolla, California, ana...

Timing is everything: First step in protein building revealed

...released completelyin living creatures, but in our laboratory experiments that is clearlythe case," adds Lorsch. "Even if it isn't released completely in intactcells, our results would indicate that it must be very looselyassociated for translation [protein building] to begin."To monitor what was happening to e...

UW's Rosetta software to unlock secrets of many human proteins

...hey are structured," said Lars Malmstroemof the UW laboratory that developed the program, "And how they arestruc... shape of the protein.Rosetta was developed in the laboratory of UW Professor David Baker bya large team of scientists and students. Former post-doctoral fellowRi...

Plants, animals share molecular growth mechanisms

...Chunhua Zhang and Gregore Koliantz; Eileen Malley, laboratory manager, all of the Department of Agronomy; and Shanjin Huang, postdoctoral student, and Christopher Staiger, professor, both of the Department of Biological Sciences. Staiger and Szymanski also are members of the Purdue Motility Group. Related Webs...

Researchers find how protein allows insects to detect and respond to pheromones

...hey are structured," said Lars Malmstroemof the UW laboratory that developed the program, "And how they arestruc... shape of the protein.Rosetta was developed in the laboratory of UW Professor David Baker bya large team of scientists and students. Former post-doctoral fellowRi...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...etermine causes of variability, and they foundthat laboratory practices comprised the smallest source of variation inthese studies. Measurement errors common to all labs were the next mostcommon contributor, and biological differences in different sampleswere the largest source of variation.“This study indicate...

Ancient olfaction protein is shared by many bugs, offering new pest control target

...ent insect species. Research by Leslie Vosshall's laboratory had previously shown that of 62 odorant-receptor proteins expressed by fruit flies, 61 are exclusively expressed in non-overlapping sub-populations of neurons, indicating that these proteins participate in sensing particular types of odors. However, ...

Genome-wide mouse study yields link to human leukemia

...l Therapeutics Programs. While it was Caligiuri's laboratory that designed the mouse model, it was Plass who supervised the methylation studies. He and his colleagues used a system called Restriction Landmark Genome Sequencing (RLGS) to compare methylation patterns among the three groups of mice ?a method of u...

Found: Missing sequence of the human Y chromosome

...males in the human population, members ofRappold's laboratory ?including Stefan Kirsch, Ph.D., lead author onthe paper ?tested 100 men of different ethnic origin for the presenceof this 554-kilobase fragment. Indeed, the sequence was present in all100 individuals tested, but not in any female controls, confirmi...

Marburg virus disease in Angola - update

...ted in Uige Province. Ten of these cases have been laboratory confirmed by the Centers for Disease Control and P...icrobiology Laboratory will be setting up a mobile laboratory in Uige and CDC will be providing laboratory support in Luanda. UNICEF is carrying out social mobili...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...ial of Revlimid for treatment of MDS following his laboratory observations that the agent improved the growth of red blood cell precursors from MDS bone marrow. Celgene will submit the seminal findings of List's phase I trial - along with data from two recent confirmatory phase II clinical trials performed nati...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...rgies successfully prevented allergic reactions in laboratory mice, as well as in human cells in a test tube, University of California, Los Angeles (UCLA) researchers report in the April issue of Nature Medicine, available online now. In the future, the investigators say, these promising results could lead to a...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

Research in the laboratory of Assistant Professor Frank J. Slack at Yale University has identified a new way that a familiar gene is regulated in lung cancer, presenting new possibilities for diagnosis and treatment. The work is reported in March issues of the journals Cell an...

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