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Tag: "known" at biology news

Timing is everything: First step in protein building revealed

...es other than a particularthree-block piece of RNA known as the "start codon." And excessiveamounts of eIF1...The researchers successfully used this phenomenon, known asfluorescence resonance energy transfer or FRET, to monitor therelationship between eIF1 and its re...

UW's Rosetta software to unlock secrets of many human proteins

...dvantagein the fight against disease.The software, known as Rosetta, predicts how proteins fold, informatio...approximately 60 percent of human proteins with no known function. "Howproteins fold determines how they are structured," said Lars Malmstroemof the UW labo...

Plants, animals share molecular growth mechanisms

...ungal attacks," Szymanski said. A protein complex known as Actin Related Protein 2/3 (ARP2/3) is a cellula...eviously had learned that a large protein complex, known as WAVE, activated ARP2/3, but they didn't know specifically which WAVE protein was the actual switc...

Researchers find how protein allows insects to detect and respond to pheromones

...dvantagein the fight against disease.The software, known as Rosetta, predicts how proteins fold, informatio...approximately 60 percent of human proteins with no known function. "Howproteins fold determines how they are structured," said Lars Malmstroemof the UW labo...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...tually be the most reliable indicator of prognosis known to date. After discussing B lymphocytes -- the type of white blood cell that gives rise to CLL, the biology of leukemic lymphocytes and the clinical course of CLL as it relates to the biology, the authors then offer a unifying hypothesis for the dev...

Researchers Uncover Key Step In Manufacture of Memory Protein

...the National Institutes of Health. The protein is known as mBDNF, which stands for mature brain-derived ne...special rafts of fatty, cholesterol-rich molecules known as lipids. If this binding process does not take place, proBDNF cannot be converted to its active fo...

Novel antiviral technology inhibits RSV infection in mice

...obiotech Inc., used a revolutionary new technology known as RNAinterference, or gene silencing, to knock ou...ply in the lungs. The virus harnesses thisprotein, known as NS1, to block the body's own antiviral response,which would normally kill RSV before it could gai...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...ng the detector at each mass-to-charge ratio (also known as m/z ratio) is recorded to produce a protein spectrum. A peak in the graph of the spectrum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and...

New species from old data

...ng the detector at each mass-to-charge ratio (also known as m/z ratio) is recorded to produce a protein spectrum. A peak in the graph of the spectrum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and...

Cracking the olfactory code in bees

...ng the detector at each mass-to-charge ratio (also known as m/z ratio) is recorded to produce a protein spectrum. A peak in the graph of the spectrum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and...

Signaling protein builds bigger, better bones in mice

...ng the detector at each mass-to-charge ratio (also known as m/z ratio) is recorded to produce a protein spectrum. A peak in the graph of the spectrum represents a protein (the identity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

... infect animals. In humans,coronaviruses have been known primarily for causing colds or, morerecently, seve...l building blocks of the gene differedfrom that of known human coronaviruses. The Yale investigators, termingthe novel virus indicated by their findings the ...

New Technique for Tracking Gene Regulators

...ehuman-genome binding sites of a regulator protein known as CREB.“Though scientists have now decoded almost all of the entire humangenome ?the series of nucleotide bases (labeled A, T, G, and C) thatmake up the source code for running the machinery of the cell ?we arejust beginning to decipher it,?said bio...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...cts on wing structure in flies, Notch signaling is known to beimportant in a number of neural cell fate det...g proteins for degradation by a wastedisposal unit known as a proteasome. Hayashi et al. sought to study thepossibility that ubiquitination might play a part...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

... the discovery about a class of prescription drugs known as "HIV protease inhibitors." Drugs in this class go by the generic names of lopinavir, nelfinavir, indinavir, ritonavir and saquinavir. Brand names include Kaletra, Viracept, Crixivan, Norvir and Fortovase. The researchers emphasize that the drugs'...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

... cause. Other genes affected by ironstarvation are known to be vital in generating energy, copying thecell's genetic code and protecting the cell from free radicals andaging, said Thiele."We discovered that iron deprivation actually reprograms the metabolismof the entire cell," said Thiele. "Literally hund...

Learning to fight an adversary that won't stay down

...ays Dr. Davies. "There are more than 300 genes now known that confer resistance to one or more antimicrobials. And they keep coming." However, the mapping of bacterial genomes has not yet helped yield solutions to the problem, says Dr. Davies. He adds that our understanding of the activity of microbes mu...

Novel Enzyme Shows Potential As An Anti-HIV Target

...her proteins. Of the three classes of deacetylases known to modify human histones, the sirtuins (SIRT1?) appear to preferentially target a number of nonhistone proteins. Ott and colleagues first tested the ability of all seven SIRT proteins to deacetylate Tat by placing them in a test tube with Tat protein...

Scientists seek answers on what activates deadly anthrax spores

...id the group proposes that a vitamin B5 derivative known as Coenzyme A plays a crucial role in the germinat... genome sequences of four strains of the bacteria, known scientifically as Bacillus anthracis, have been determined. The group also will be exploring the th...

U of M researcher examines newly emerging deadly disease

...ed in seven additional cases nationwide. Of the 12 known cases, only two patients have survived. Purpura fulminans is an acute illness commonly associated with meningococcemia or invasive streptococcal disease, and it is typically characterized by the depletion of clotting factors in the blood and skin le...

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