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Tag: "killing" at biology news

Lack of a key enzyme dramatically increases resistance to sepsis

... the leading causes of death in the United States, killing more than 200,000 people each year, according to the Society of Critical Care Medicine. A 2003 study by The Centers for Disease Control and Emory University School of Medicine showed that the incidence of sepsis in the United States has increased alm...

Chemical guidance of T cells leads to immunologic memory and long-term immunity

...hich then sweep through the body, hunting down and killing infected cells. For CD8+ T-cell activation to occur in the lymph node, the cell must encounter its target antigen--but that antigen must be displayed on the surface of another immune system cell, called a dendritic cell. Usually a third type of cel...

Movement of chromosome in nucleus visualized

... method that allowed them to take pictures without killing the movement. Using this system, UIUC graduate student Chien-Hui Chuang studied a chromosome that is normally found in an inactive state near the nuclear periphery and moves to the interior of the nucleus when it receives an activating signal. "T...

Polymer aids in blood clotting, pointing way to new treatment

...c organelles and suggesting a targeted approach to killing many disease-causing organisms. "Because I saw electron microscopy pictures of the blood platelets' dense granules taken many years ago that were almost identical to the pictures we took of the acidocalcisomes of different protozoa," Docampos said, ...

Climate change drives widespread amphibian extinctions

...hem into the abyss. "Disease is the bullet that's killing the frogs," said J. Alan Pounds, the study's lead scientist affiliated with the Tropical Science Center's Monteverde Cloud Forest Preserve in Costa Rica. "But climate change is pulling the trigger. Global warming is wreaking havoc on amphibians, and ...

Scientists discover a new disease-causing bacterium in an immune-compromised patient

...nism may shed light on the mechanisms of microbial killing in CGD. Comparing the genome of this organism to other 13 available genomes of CGD pathogens may provide clues to virulence properties that they share in common," according to the article. ...

Soil-bound prions that cause CWD remain infectious

...nism may shed light on the mechanisms of microbial killing in CGD. Comparing the genome of this organism to other 13 available genomes of CGD pathogens may provide clues to virulence properties that they share in common," according to the article. ...

Biologists visualize protein interaction that may initiate viral infection

...oes, infects more than 50 million people annually, killing about 24,000 each year, primarily in tropical regions. During the earliest stages of infection, the dengue virus attaches to the "carbohydrate recognition domain," or CRD, of a key binding protein called DC-SIGN, located on a host cell's surface. U...

Unraveling the mysteries of poison

...ectric signals to move through the membrane ?often killing the cell. These kind of interactions had not been well investigated at a structural level ?even though scientists had made great strides studying ion channels, using x-ray crystallography. Scientists from the Max Planck Institute for Biophysical Che...

New antimicrobial compound adheres to skin to promote healing

...for use as a combination cleanser and ointment for killing acne-causing bacteria. ...

Scientists develop malaria forecasting tool to predict disease risk

... Malaria is one of the world's deadliest diseases, killing more than one million people every year, as well as infecting a further 500 million worldwide. The mosquito-borne illness is endemic in several regions globally, but is most acute in Africa, home to an estimated 90 per cent of all cases. Dr Andy ...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

... two potent cancer-fighting drugs are effective in killing human breast tumors. The unique properties of the hollow shell nano-particles, known as polymersomes, allow them to deliver two distinct drugs, paclitaxel, the leading cancer drug known by brand names such as Taxol, and doxorubicin directly to tumor...

Molecular force field helps cancer cells defend against attack

...field of their own to fend off treatments aimed at killing them. Now University of Florida researchers have found a chink in their armor. The cells churn out an enzyme that bonds with a protein, creating a protective barrier that deflects damage from radiation or chemotherapy and promotes tumor cell surviva...

VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum

... he said. "The effectiveness of a platinum drug in killing cells is directly related to its concentration inside the cell." DNA-damaging agents, such as cisplatin, are among the most effective classes of compounds in clinical use for the treatment of cancer. The principal function of cisplatin is to bind t...

Newly discovered killer cell fights cancer

...stave Roussy, tested whether IKDCs are culprits in killing cancer by injecting mice with a cancer drug called Gleevec, which blocks an abnormal protein produced by cancer cells, and a growth factor for NK cells. The drug-growth factor combo served as a lure, leading the IKDCs to tumors implanted in the mice...

New device could cut chemotherapy deaths

...rest of the body. This is a more localised way of killing cancer cells than the current method of injecting the chemical into a cancer sufferer's vein so that it is carried around the body. As well as reducing the side-effects, the new drug delivery vehicle, known as Fibrasorb, could also cut the numbers o...

Cincinnati surgeons report new treatment for often-fatal injury

... the damaged aorta quickly before it does rupture, killing the patient. The Food and Drug Administration has yet to approve a device for treatment of this type of injury, says Dr. Giglia, and custom-made devices are usually large and difficult to use in an emergency setting. Dr. Giglia's team found that...

Scientist-astronaut sends T-cells into space

...bia broke up upon reentry into Earth's atmosphere, killing all seven crew members and destroying all experiments aboard. "We cannot go to Mars, or even to the Moon over the long term, without knowing more about why T-cells are not working," says Hughes-Fulford. "When we learn that, we can start looking fo...

New pathways for autoimmune treatment identified

...ine. "The body should maintain a balance between killing and suppression," says Dr. Qing-Sheng Mi, immunologist and lead and co-senior author. "If you are killing too hard, it can induce autoimmune disease. If you regulate suppression too hard, you can get cancer...

Widespread elephant slaughter discovered in Chad

...he days just before they were found. At one of the killing sites Fay observed a camp with six horses and five men, who quickly packed up as the plane flew over. "Zakouma elephants are getting massacred right before our eyes," Fay said. "We hadn't been in the air more than two hours when we saw our first car...

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