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Tag: "killed" at biology news

Common cancer gene sends death order to tiny killer

...to put miR-34a into colon cancer cells. Doing this killed cells that contained p53, but fewer were killed in cells lacking p53, further suggesting that this microRNA gets its kill orders from p53. When r...

Newly found sensing system enables certain bacteria to resist human immune defenses

...soning, skin disorders and toxic shock—avoid being killed by AMPs. AMPs are made by virtually all groups of organisms, including amphibians, insects, several invertebrates and mammals, including humans. “Gram-positive bacteria are major threats to human health, especially due to increasing problems with ...

How 'memory' T cells curb the spread of viruses throughout the body

... “In fact we found that memory CD8 T cells already killed target cells in the lymph node and decreased viral spread to the liver and spleen when the virus just barely started to multiply.” Thus, memory CD8 T cells do not prevent infection; but prevent disease partly because they curb the spread of the vi...

Revealed -- Mosquito genes that could be controlling the spread of killer viruses

...ogen either survives inside the insect body, or is killed by the insect’s defences.” The international research team, led by Imperial PhD student Robert Waterhouse, focused on comparing the immunity genes of the Aedes mosquito with similar groups of genes in the harmless fruit fly and the Anopheles mosqu...

New vaccine prevents CMV infection and disease in mice

...sential genes required for CMV replication, with a killed virus that prompts the body’s B-cells to generate an antibody response. The vaccine contains the DNA of two essential genes that are essential for replication of the virus. These genes – which are also found in other herpes viruses such as chi...

How plague-causing bacteria disarm host defense

...onic plague (also known as the Black Death), which killed more than 200 million people in the Middle Ages. "This bacterial species could still be a threat today," said Navarro, adding that scientists had isolated an antibiotic-resistant strain of this species. In addition Y. pseudotuberculosis and Y. en...

Genome of Clostridium botulinum reveals the background to world's deadliest toxin

...ost can be quickly overpowered and, in some cases, killed by the toxin, and C. botulinum has a new food source. "Although in the same group as Clostridium difficile — the Cdiff superbug — C. botulinum has a genome that is remarkable because it is so stable," commented Dr Mohammed Sebaihia, lead author o...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...ells from reaching the site of infection. Anthrax killed five people in 2001 when letters containing the bacteria's spores were sent through the mail. The UF findings, published last week in the EMBO Journal, may lead to quicker diagnoses for anthrax victims. The disease causes flu-like symptoms that ca...

DNA analysis suggests under-reported kills of threatened whales

...th Korea reported to the IWC just 458 minke whales killed overall during that five-year period, Baker said, ...und far fewer individuals ?or the number of whales killed is actually much greater than is being reported." To estimate the true number of whales in trade,...

Gut research yields new anti-cancer approach

...d that medium-to-high doses of PPARgamma inhibitor killed colorectal cancer cell lines. Despite the compound...publication are studies where PPARgamma inhibitors killed tumor cells in mice without causing significant toxicity. That provides at least the hope that the d...

Male-killing bacteria makes female butterflies more promiscuous

...ound that when the male insect population drops -- killed off by the bacteria -- the female butterfly becomes more sexually rampant. Males on the other hand show signs of fatigue and put less effort into mating. In some populations of tropical butterfly the entire mating system is determined by a group ...

NIAID DNA vaccine for H5N1 avian influenza enters human trial

... hens' eggs and then administered as a weakened or killed form of the virus, DNA-based vaccines contain only portions of the influenza virus' genetic material. Once inside the body, the DNA instructs human cells to make proteins that act as a vaccine against the virus. VRC Director Gary Nabel, M.D., Ph....

Ebola outbreaks killing thousands of gorillas and chimpanzees

Why have large outbreaks of Ebola virus killed tens of thousands of gorillas and chimpanzees over...ons for controlling the impact of Ebola, which has killed roughly one quarter of the world gorilla population. "It means that vaccinating one gorilla does not...

World's largest flower evolved from family of much tinier blooms

...in some cases even emit heat, much like a recently killed animal. These traits help the flower attract the carrion flies that pollinate it. "While it's surprising to find this giant plant evolved from a family typified by much smaller blossoms, rafflesia is unusual enough that it's frankly been difficult ...

Canada's new government invests $200M in the fight against the mountain pine beetle

...the beetle; recovering economic value from trees killed by the beetles; and protecting communities and forest resources in areas affected by the infestation. Project activities will include measures to control the eastward spread of the beetle in British Columbia and along the British Columbia–Al...

Dual gene therapy suppresses lung cancer in preclinical test

...h the gene combination had 2 to 3 times more cells killed by apoptosis than either gene nanoparticle had individually. The research team then confirmed these findings in the mouse studies. The nanoparticle delivery system, which the researchers have used for years, consists of a plasmid gene expression c...

Trojan horse strategy defeats drug-resistant bacteria

...roach. Rather than trying to find agents that best killed bacteria in test tubes, they sought to intensify t...al cells." The researchers showed that gallium killed microbes, and prevented the formation of biofilms. Importantly, gallium's action was intensified in...

Are journal rankings distorting science?

... who should know better," he writes. "It should be killed off, and the sooner the better." But Richard Hobbs of Birmingham University thinks that rather than just discarding impact factors we should consider solutions to the problems. For example, extending the citation surveillance period, applying weig...

Gallium: A new antibacterial agent?

... responsible for chronic bacterial infections, and killed both free-living bacteria and bacteria in biofilms. Furthermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lung infections. As Ga is already FDA approved for the treatment of hypercalcemia of malignancy, these data su...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...ears of lingering mysteries about the illness that killed the French emperor during his island exile, a UT Southwestern Medical Center scientist reports. American, Swiss and Canadian researchers applied modern pathological and tumor-staging methods to historical accounts and found that Napoleon died of a ...

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