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Tag: "kill" at biology news

Common cancer gene sends death order to tiny killer

...-34a that participates in p53's uncanny ability to kill cells likely to become malignant because of damage...53, further suggesting that this microRNA gets its kill orders from p53. When researchers examined pancreatic cancer cells known to contain damaged or mi...

Cells re-energize to come back from the brink of death

...ck this backup program would allow that program to kill the cell. Such a specifically targeted drug might ...from CICD suggests that blocking this enzyme would kill abnormal cells that lack caspase activation and cannot undergo apoptosis. That strategy would be the...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

... how future drugs might be designed to effectively kill the parasite," said Paul Roepe, Ph.D., a professor in the Department of Biochemistry and Cellular & Molecular Biology as well as the Department of Chemistry. Any animal with red blood cells can develop malaria, which is caused by a single-cel...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...py and more focused radiation therapy, designed to kill rapidly spreading cancer cells, also can destroy dynamic reproductive tissue. “I don’t think when you are faced with the reality that you may die, your fertility is the most important thing you are thinking or talking about, but there are a lot o...

Newly found sensing system enables certain bacteria to resist human immune defenses

...), which are defense molecules sent by the body to kill bacteria. Bacteria are divided into two types, gram-positive and gram-negative, with the primary difference being the nature of the bacterial cell wall. Little is known about how gram-positive bacteria—such as those that can lead to food poisoning, ...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...then exposed to light, causing them to heat up and kill only those diseased cells, Akin said....

How 'memory' T cells curb the spread of viruses throughout the body

... lymph nodes and then migrate through the blood to kill infected cells at the site where the virus entered... show that memory CD8 T cells rapidly multiply and kill target cells inside the lymph node. “In fact we found that memory CD8 T cells already killed tar...

Genome of Clostridium botulinum reveals the background to world's deadliest toxin

...g — the weight of two bags of sugar — is enough to kill every person on the planet. Very small amounts of the same toxin are used in medical treatments, one of which is known as Botox®. The genome sequence shows that C. botulinum doesn’t have subtle tools to evade our human defences or tricky methods of ...

Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host

... single gene to out-fox insect immune defences and kill its host. In research published in the journal Pr...cteria that in relatively small concentrations can kill insects - between 10-100 cells of it are typically enough ?but most are harmless to humans and can b...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...d. "Neutrophils have to get to the infection to kill anything. If you paralyze them so they don't move, they can't protect you," said Fred Southwick, M.D., division chief of infectious diseases at the UF College of Medicine and the study's lead author. But exactly how the anthrax toxin wards off neu...

Dealing deadly cancers a knockout punch

...l to burst, which releases viruses that infect and kill adjacent cancer cells. Normal cells are not harmed. In addition to killing cancer cells directly, reovirus is believed to activate an anti-tumor immune response through the body's natural killer cells and T cells. Through this mechanism, which pe...

Herpes infection may be symbiotic, help beat back some bacteria

...ria replicated more slowly and were less likely to kill the mice. When herpes was still in the acute phase of infection, no protective effect was present. When scientists exposed the mice to a mutant herpes virus that can infect but cannot establish latency, the herpes infection did not confer resistan...

Gene thought to assist chemo may help cancer thrive

...ne thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive. In a new study of chemo patients, scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute found that 70 percent of subjects whose tumors had mutations in the gene p53 were still ...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...I allows the immune system to identify, target and kill cells that have already become infected, something antibodies can not do. The determine the cause of this effect, Wilson-Welder and her colleagues next incubated human dendritic cells in the presence of polyanhydride microspheres (without ovalbumi...

Researchers wake up viruses inside tumors to image and then destroy cancers

... FIAU light up the tumors, it can also potentially kill them, Pomper says. For imaging purposes, FIAU can carry a radionuclide that emits a low energy gamma photon, but it can also be engineered to carry therapeutic radionuclides, which are lethal to cells in which TK is activated. Results of this stud...

Leeches ferry infection among newts

...mphibians in North America. It does not appear to kill amphibians but might affect their ability to reproduce. "This is the first evidence that newts are getting infected through the bites of leeches," said Thomas R. Raffel, a postdoctoral researcher at Penn State's Center for Infectious Disease Dynam...

Studies force new view on biology of flavonoids

..."Flavonoids could also induce mechanisms that help kill cancer cells and inhibit tumor invasion," Frei added. It also appears that flavonoids increase the activation of existing nitric oxide synthase, which has the effect of keeping blood vessels healthy and relaxed, preventing inflammation, and loweri...

Investigating the measles virus as a tool to kill multiple myeloma

...es in patients testing the potential of measles to kill cancer. “This is the beginning of a long but exciting process,?says Angela Dispenzieri, M.D., hematologist and lead researcher on the multiple myeloma clinical trial in the measles virus investigation. “We are very hopeful that this will be a step ...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...d to the bioprobes was observed. "Using heat to kill cancer cells isn't a new concept," DeNardo said. "The biggest problems have been how to apply it to the tumor alone, how to predict the amount needed and how to determine its effectiveness. By combining nanotechnology, focused AMF therapy and quantit...

Arsenic in chicken feed may pose health risks to humans, C&EN reports

...e used in chicken feed, is used to promote growth, kill parasites and improve pigmentation of chicken meat. In its original form, roxarsone is relatively benign. But under certain anaerobic conditions, within live chickens and on farm land, the compound is converted into more toxic forms of inorganic arse...

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