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Tag: "kidneys" at biology news

Bioartificial kidney under study at MCG

...urs of dialysis three to four times a week. Since kidneys are constantly working, it may seem logical that l... of dialysis have only replaced the ability of the kidneys to rid the body of waste products and correct abnormalities in blood chemistry; they don't replace k...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

...pid uptake and clearance of the drug in the heart, kidneys and lungs, with slower uptake in the liver and brain. In the fetus, cocaine accumulated at the highest levels in the liver (due to the unique anatomy of fetal circulation) and to a lesser extent in the brain. "While the uptake of the tracer into the...

Next Generation Body Scanner Launched By The University Of Manchester

...ther. Researchers working on abnormalities in the kidneys will also benefit from the improved scanning, rese...rsity to investigate vascular abnormalities to the kidneys in patients with renal disease. The scanner, which has been manufactured by Philips Medical Systems...

A probe, not an echo

...roficiency in imaging animal tissue, notably sheep kidneys and bovine liver. The most critical feature of the HUTT imaging technology is its potential to reliably differentiate types of tissue based on their multi-band signatures caused by their varying attenuation patterns. This promises to allow non-invas...

Newly discovered genetic disease sheds light on body's water balance

...V2R) for vasopressin, a hormone that instructs the kidneys to retain water. Neither patient was producing mea...V2 receptor on cells in the collecting duct of the kidneys remained activated as if it was binding to the hormone. Both mutations activate the receptor by cha...

New type of rejection blocker protects kidneys after transplant

...owed that all patients retained their transplanted kidneys except for one in the intensive belatacept group a... waste -- as an indicator of how well transplanted kidneys were functioning. The GFR was significantly higher at 12 months for patients receiving both the inte...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

...caused by ischemia, or loss of blood supply to the kidneys caused by shock, blood infection or major cardiova...s and then 'disappeared.' But after entry into the kidneys with ARF, we found that they fundamentally changed a number of important gene expression profiles. I...

Enzyme affects hypertension by controlling salt levels in body

...owever, if salt ingestion remains the same and the kidneys reabsorb 99.9 percent of salt, too much salt returns to the blood, increasing blood volume and leading to hypertension. If less than 99 percent is absorbed, low blood pressure develops. Dr. Huang said that not everyone who eats too much salt ends up...

Membrane research opens window to benefits for plants, humans

...als that specifically target these proteins. "The kidneys are responsible for maintaining a water balance in the body," said Swedish co-author Per Kjellbom in a Lund University news release. "If we can identify a chemical compound that can close the aquaporins in the kidneys, this can be developed into a di...

Manipulating single cell receptor alters animal behavior

...t the molecular level. Daniels explains that the kidneys and lungs produce enzymes that eventually provoke production of angiotensin. It previously was known that angiotensin has robust behavioral effects on animals, causing them to drink water and consume salt. It was also known that angiotensin acts on...

Scientists discover that widely available drug also helps fight kidney disease

...red rapamycin to mice with PKD and looked at their kidneys afterwards, we were absolutely amazed," said Weimbs. "The kidneys were smaller, had smaller cysts and had retained their function." "We have known the genetic mutati...

Weighting cancer drugs to make them hit tumors harder

...d into the bloodstream, nor can they penetrate the kidneys to be cleared from the body. They must wait for the liver to break them up and dispose of them via the intestines. "Our goal was to increase the tumor dose and lower the systemic dose," said Chilkoti. "Macromolecular drug carriers are an attractive ...

U of M study examines kidney stone prevention in astronauts

...ne now. Kidney stones are mineral deposits in the kidneys that can travel through the urinary tract, causing intense pain. One of the most common types of kidney stones is caused by the buildup of calcium oxalate. Researchers studied the effects of exercise in pairs of identical twins, since a portion of ...

Species unique to tidal marshes face threats

...ty by relatively impermeable skin, and others have kidneys that can concentrate salts from large volumes of water or specialized glands that exude salt. Many are gray or black in color, which is believed to be an advantage because it matches the dark color of the soils often found in tidal marshes. Why endem...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

... used an antibody to identify where aqp2 is in the kidneys of the mutant mice, they saw that distribution of the protein was changed. Normally aqp2 is concentrated on the side of collection duct cells that faces the urine, where aqp2 can extract water from the waste stream for recirculation in the body. In t...

Pure carbon nanotubes pass first in vivo test

...d, also revealed trace amounts of nanotubes in the kidneys ?another common expulsion route for drugs. There was no evidence that nanotubes remained in other tissues in the body. Nanotubes are hollow cylinders of pure carbon that measure just one nanometer in diameter ?about the same width as a strand of D...

Climate change has surprising effect on endangered naked carp

... to river-water fish. Ammonia-N secretion by the kidneys declines by a surprising 70 percent, and urine flow decreases drastically to less than 5 percent of its rate in the freshwater river water. "In other words, the kidney changed from an organ which excreted water at a greater rate than salt in river...

Key gene controlling kidney development found

... this project. The St. Jude team showed that the kidneys in developing mice lacking the Six2 gene were remarkably smaller than normal mice and were non-functional at birth. In addition, they produced an abnormal excess in the number of nephrons that in turn produced a useless mass of tissue. Furthermore, t...

Scientists explore how complex organs develop from a simple bud

...tal development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation. Ultimately, scientists hope analysis of branching morphogenesis will lead to the design of a computer program that is able to virtually reconstru...

Growth hormone to boost athletic performance risks diabetes

... Tests revealed that his liver was inflamed, his kidneys were enlarged and that he had very high blood sugar. He was also dehydrated, and diagnosed with diabetes. He was given intravenous fluids and gradually increasing amounts of insulin over five days, after which he was discharged. His symptoms compl...

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