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Tag: "key" at biology news

Some Brain Cells Change Channels

...g ability has been recognized for a few years, the key players controlling it hadn't been identified. Now, by studying mice, the Hopkins team has identified two proteins, called PICK1 and NSF for short, that help replace channels that let charged calcium ions in with another kind of channel that keeps ca...

Newly discovered protein an important tool for sleeping sickness research

...at a uniquely modified DNA base called base J is a key component of the trypanosome's mechanism for evadi...s were able to demonstrate that the protein is the key regulator of base J synthesis. This will provide the scientists a new tool to elucidate the biologic...

Breakthrough System for Understanding Ocean Plant Life Announced

...at a uniquely modified DNA base called base J is a key component of the trypanosome's mechanism for evadi...s were able to demonstrate that the protein is the key regulator of base J synthesis. This will provide the scientists a new tool to elucidate the biologic...

NYU, Rockefeller researchers find complexity of regulation by microRNA genes

...oRNA genes, which have recently been shown to have key roles in gene regulation, can team up and regulate target genes in mammals. MicroRNAs are a recently discovered large class of regulatory, non-coding genes, which bind to partially complementary sites in target messenger RNA to regulate their stabili...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

...e specificity of a drug, and NAADP could provide a key in the area of obesity." In another therapeutic arena, she notes, Viagra is the world's most successful and recognized secondary messenger targeting drug to reach the market. Cholecystokinin, a first messenger, activates NAADP; so which is 'therape...

Searching the depths of the straits of Florida for disease cures

...t explored. Besides looking for unusual species, a key goal will be to gather samples of a sponge collected last May that produces chemicals currently showing potential in fighting pancreatic cancer. The upcoming expedition is being supported through funds appropriated by the Florida legislature and app...

Life detection instrument passes key test on road to Mars

...sert was selected by NASA scientists as one of the key spots to test instruments destined for Mars, primarily because of its oxidizing, acidic soil, which is similar to the rusty red oxidized iron surface of Mars. Skelley and colleagues Pascale Ehrenfreund, professor of astrochemistry at Leiden Universit...

Roundup®highly lethal to amphibians, finds University of Pittsburgh researcher

...n a natural setting, and the results may provide a key link to global amphibian declines. In a paper titled "The Impact of Insecticides and Herbicides on the Biodiversity and Productivity of Aquatic Communities," published in the journal Ecological Applications, Relyea examined how a pond's entire commu...

DNA constraints control structure of attached macromolecules

...ecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constraints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to contr...

UN successfully tests 'green' pesticide against locusts

...ecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constraints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to contr...

Health costs soar as 60 million Americans classed as obese

...ecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constraints on one molecule, we could generate multiple molecular states that would be programmable by DNA sequence. In other efforts, we would like to contr...

Community MRSA is re-emergence of 1950s pandemic, study suggests

...tions. Now researchers have shown that one of the key clones of community acquired MRSA (CA-MRSA) - infe...ic-causing strain. The researchers have sequenced key genes from 80/81 samples isolated between 1955 and 1969 in Australia, England and the USA, and compa...

New understanding of cell movement may yield ways to brake cancer's spread

...ri and her team found a molecule called DOCK180, a key signaling protein that binds to PIP3. PIP3 is a lipid that accumulates on the leading edge of a cell about to move, usually in response to a number of outside cellular attractants like chemokines, growth factors and other molecules. Meanwhile at the ...

Researchers discover key gene involved in bark beetle pheromone production

...ie. University researchers have characterized the key gene in the beetles' monoterpene biosynthesis, which will allow further research into ways to disrupt the production of aggregation pheromone. In addition to Blomquist, Anna Gilg, Jeremy Bearfield, Claus Tittiger and William Welch co-authored the ar...

Key to elephant conservation is 'in the sauce'

...on? They both feel the burn of chilli peppers, the key ingredient for resolving human-elephant conflicts in Africa while raising money for farmers and conservation. Supported by the Wildlife Conservation Society (WCS) and other groups, the Elephant Pepper Development Trust (EPDT) has not only promoted t...

Critical step traced in anthrax infection

...rd Medical School (HMS) have revealed details of a key step in the entry of anthrax toxin into human cells. The work, which grew out of an ongoing effort to produce a better anthrax therapeutic, shows that the protective antigen component of the bacterial toxin plays an active role in transferring the ot...

Malaria mechanism revealed

...tallography to determine the atomic structure of a key portion of the EBA-175 protein called the RII doma...available on request) "We now see precisely how a key part of a malaria parasite protein works. This enables researchers to design very specific wrenches ...

Immune system's distress signal tells bacteria when to strike back

...ays. Alverdy and colleagues were able to pinpoint key early steps of this lethal process. The transformation starts when a weakened host tries to boost its defenses against any possible invasion. The host's T cells release chemical signals that activate the immune system. One of those signals, interfero...

Random gene expression may drive HIV into hiding

...s that could enter human cells, carrying with it a key component of HIV's replication machinery: a gene called Tat. Tat facilitates transcription of HIV's entire genome, including itself, which creates a positive-feedback loop: If a little bit of Tat is around, then the HIV genome is transcribed efficien...

Scientists discover global pattern of big fish diversity in open oceans

...eans. A robust portfolio of different species is a key to maintaining our supply of fish in the long term...entists, is that there is hope for the future. The key pieces of the global biodiversity puzzle are still out there, including the physical structures upon...

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