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Tag: "key" at biology news

The making and breaking of microtubules

...ility," this ongoing rapid growth and shrinkage is key to the diverse workings of microtubules in the cel...t the brakes on the project for a long time. "The key was to get the tubulin assemblies locked at the correct states suitable for structural analysis, but...

Excess liver gene protects against high-fat diet

...etabolic genes. "Liver X receptors had emerged as key regulators of cholesterol and lipid metabolism," said Lazar. "The current study elucidates a previously unrecognized role for these liver receptors in the links between diet, serum lipids, and atherosclerosis." Selective modulation of the LXR target...

Open Access journals get impressive impact factors

...ms. The impact factors also demonstrate one of the key benefits that Open Access offers authors: high visibility and, as a result, a high rate of citation." ...

Fat's fate depends on its source

...rol. Those genes are normally targeted by PPARa, a key energy management gene activated by fatty acids. "In short, all fatty acids are not created equal, at least in the liver," Semenkovich said. The findings suggest that products of fatty acid synthesis regulate glucose, lipid, and cholesterol metabol...

'Bionic' arm gives amputee sense of touch

...ms. The impact factors also demonstrate one of the key benefits that Open Access offers authors: high visibility and, as a result, a high rate of citation." ...

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments

...e called prokineticin 2 (PK2), was found to play a key regulatory role for the proper functional integration of these new neurons in the brain. A few years ago, PK2 was shown by the same research group to be an important regulator of circadian rhythms. The current study appears in the June 24 issue of th...

Combination therapy leads to partial recovery from spinal cord injury in rats

...oped into myelin-producing oligodendrocytes. "The key word here is 'combination.' This is one of a series of new studies showing that a combination of therapies is needed for successful spinal repair, in this case, specialized cells and growth factors. The experiments also used a combination of outcomes...

Small worm yields big clue on muscle receptor action

...tylcholine response. ACR-16 was singled out as the key subunit. "We've shown the ACR-16-containing receptor is present in muscle and contributes hugely to the synaptic current," said Richmond. "Now we can tag this receptor, see if it's localized at the synapse and start to mutagenize animals to figure ...

Study: Well-known protein helps stem cells become secretory cells

... help fix that problem, the researchers note. "The key is knowing how pancreatic cells know what hormones to produce and release, or how any gland does, and the new findings add to that knowledge," says Deborah Andrew, Ph.D., professor of cell biology in Johns Hopkins' Institute for Basic Biomedical Scie...

Depression gene may weaken mood-regulating circuit

...ansporter gene." Since serotonin activity plays a key role in wiring the brain's emotion processing circuitry during early development, the researchers propose that the short variant leads to stunted coupling in the circuit, a poorly regulated amygdala response and impaired emotional reactivity ?resulti...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

...teria, but also how much of each is produced - the key to understanding the role each bacterial species p... Leptospirillum group II bacterium appears to be a key protein in the production of acid mine drainage. The protein, a cytochrome, oxidizes iron, and thus ...

UCR chemist part of team identifying new areas of gene regulation

...regulation of gene activation and repression. The key findings of the current paper were the discovery of this acetylation at the core of the histone, rather than at the proteins' ends, which are where most gene regulation is thought to take place. The team used mass spectrometry to show that acetylatio...

Specialized immune-system B cells play double-barreled role

...t was deficient in a protein called CD19 that is a key regulator of B-1a cell function and development. T...opment," said Tedder. "However, understanding such key characteristics of the immune regulatory process will be critical to learning to successfully manipu...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...therapies for different tissues and cell types. A key advantage of the UB team's nanoparticle is its surface functionality, which allows it to be targeted to specific cells, explained Dhruba J. Bharali, Ph.D., a co-author on the paper and post-doctoral associate in the UB Department of Chemistry and UB'...

Researchers find first evidence of venom system in extinct mammal

... years ago in central Alberta has proved to be the key to answering a long unsolved evolutionary question, say researchers from the University of Alberta. Back in 1991, Dr. Richard Fox and his research team found a 60 million year-old incomplete skull fossil that they now believe is the first evidence o...

Deep thinking: Scientists sequence a cold-loving marine microbe

...es (PNAS) Online Early Edition July 25-29, reveals key biochemical tools that cold-adapted, or psychrophi...ot environments. Finally, the scientists overlaid key C. psychrerythraea protein sequences onto known 3D structures from similar proteins among the divers...

When it comes to cell entry, being average has its advantages

...l that can account for this. Particle size plays a key role. According to the team's new model, cells take in viruses and other particles with a diameter of 27 to 30 nanometers more readily than ones that are larger or smaller. The faster the viruses are absorbed, the more rapidly they reproduce. "Cells...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

... which noted that while microbial communities play key roles in the Earth's bio-geochemical cycles, scientists know little about the structure and activities within these communities. This is because the commonly used artificially cultivated organisms lack the diversity found in nature, so potentially cr...

Enlisting genomics to understand flu evolution

...ddenly became capable of infecting thousands. "The key thing here is that the general notion of epidemic flu is that there's a series of successions by variants of the flu we got the previous year." But the new study shows that persistently cocirculating minor strains--which might be accumulating mutatio...

Study shows humans have ability to track odors, much like bloodhounds

...r extracting spatial information from smell." One key difference between their experiment and previous experiments to replicate the results of von B�k�sy is that Porter and Sobel asked their subjects to actively sniff, whereas many previous experiments prevented subjects from sniffing. "We think that m...

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