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Tag: "keep" at biology news

Protein sensor for fatty acid buildup in mitochondria

...ll can "buy" all of the biochemical reactions that keep the cell alive and performing its functions. Virtually all cells have mitochondria, and disruption of their function can cause a variety of diseases. "Our study showed the connection between the location of PanK2 in the mitochondria and its role ...

DNA ends: Common tool, different job

... scientists to better understand the dynamics that keep chromosomes ends, called telomeres, intact. "Identification of this new RPA-like complex, which is targeted to a specific region of the genome, suggests that multiple RPA-like complexes have evolved, each making individual contributions to genomi...

Biologists prove critical step in membrane fusion

...s at fertilization and is particularly critical to keep hormones circulating and brain cells firing. Membrane fusion is also how HIV and other viruses infect cells. But membrane fusion occurs in less than a millisecond, making it difficult to see precisely how it unfolds. Now Brown University biologist...

No carrier necessary: This drug delivers itself

...ntists to develop innovative delivery systems that keep these drugs intact until reaching their targets. Now scientists in the University at Buffalo’s Institute for Lasers, Photonics and Biophotonics and Roswell Park Cancer Institute have developed an innovative solution in which the delivery system is t...

HIV protein enlisted to help kill cancer cells

Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death si...

Trojan horse strategy defeats drug-resistant bacteria

...the UW. "The body has potent defense mechanisms to keep iron away from infecting organisms, and invaders must steal some if they are to survive." Iron is critical for the growth of bacteria and for their ability to form biofilms, slime-encased colonies of microbes that cause many chronic infections. ...

Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment

...r) into airways, creating a thin layer of fluid to keep airways clear. However, SMase, secreted by certain respiratory tract bacteria, breaks down lipids surrounding CFTR and thereby suppresses CFTR’s chloride-passing function. To make matters worse, the products of the lipid breakdown are also known to t...

Chemical switch triggers critical cell activities

...e of several different biochemical activities that keep cells alive and functioning normally." Schulman, a Howard Hughes Medical Institute (HHMI) investigator, is senior author of the Nature report. Scientists already knew that E1 momentarily juggles two NEDD8 molecules at once, holding them in two di...

Strawberry daiquiris -- the extra-healthy cocktail?

...er, scientists show. While exploring ways to help keep strawberries fresh during storage, researchers from Thailand and the US discovered that treating the berries with alcohol led to an increase in antioxidant capacity and free radical scavenging activity within the fruit. While such a boost helped the ...

UF scientists discover new genus of frogmouth bird in Solomon Islands

...ty. "These are island adaptations that work to keep the bird on the island," Steadman said. Second, it has distinct barring on the primary wing feathers and tail feathers, where other frogmouths are more uniform. Its speckles are larger, and the white spots on its breast and underbelly are more pr...

Study uncovers a lethal secret of 1918 influenza virus

...8 flu virus may help researchers understand how to keep the virus from causing such a severe immune response. "This study in macaques, combined with our earlier research showing the host response in mice infected with the 1918 flu, suggests that the host immune response is out of control in animals infe...

UCLA/Toronto researchers unlock key to memory storage in brain

.... "If a cell is low in CREB, it is less likely to keep a memory. If the cell is high in CREB, it is more likely to store the memory." Human implications of the new research could prove profound. "By artificially manipulating CREB levels among groups of cells, we can determine where the brain store...

Scientists unlock mystery of embryonic stem cell signaling pathway

...boratory to the clinic, there needs to be a way to keep the cells growing and dividing without the use of ...ator CBP and ß-catenin, which signals the cells to keep dividing and to remain as fully potent stem cells. “This way, you can essentially maintain the stem ...

Knocking out survival protein could aid leukemia treatment

... survival protein is called Mcl1. It usually helps keep normal cells healthy and is involved in the development of the components of the immune system, but it can also help prolong survival of cancer cells. Cells with an overabundance of the protein are also more resistant to anticancer drugs such as ...

Birds found to plan for the future

... have cached where and how long ago, and they also keep track of which particular bird was watching when they cached so that they can protect their caches accordingly from being stolen by observant thieves. The research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), mark...

Ultrathin films deliver DNA as possible gene therapy tool

...NA. While electrostatic forces between the layers keep the film stable in dry, room-temperature conditions, the polymers break down easily in a wet biological environment - like the inside of a patient's body. Lynn's laboratory has engineered a whole toolbox of different polymers to fine-tune the DNA d...

A revolution in the monitoring of unborn babies

...s small and easy to use so that mother’s-to-be can keep a regular check on their baby’s heart beat without having to go into hospital and be attached to a machine. No other technology allows them to do this. It took 15 years of pioneering work and enterprise, with funding from Action Medical Research and...

Many couples choose to donate surplus embryos for stem cell research

...eir embryos for stem cell research, 44% decided to keep them in storage for their own future use, 7% opted to donate them to other infertile couples, and fewer than 1% made the decision to discard the embryos. "Among the couples who did not want to increase their family, 90% support the donation of emb...

Ring-around-the-cell

... around the cell perimeter. This ring functions to keep the bone-eating acids and enzymes produced between the cell and the bone confined to the demolition site. How does this ring form? To solve the mystery, Prof. Benjamin Geiger, Dean of Biology, and Prof. Lia Addadi of the Structural Biology Depart...

Coated nanoparticles solve sticky drug-delivery problem

...ody have an undesirable side effect: they can also keep helpful medications away. To overcome this hurdle,...us barriers evolved to serve a helpful purpose: to keep things out," said Justin Hanes, an associate professor of chemical and biomolecular engineering who ...

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