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Tag: "junction" at biology news

Conceptualizing a cyborg

... the January issue of Neurosurgery. "We're at a junction now of developing a new approach for a brain-machine interface," says senior author Douglas H. Smith, MD, Professor of Neurosurgery and Director of the Center for Brain Injury and Repair at Penn. "The nervous system will certainly rebel if you place ...

Fast-freeze snapshot yields new picture of nerve-muscle junction

...a snapshot of what's going on at the neuromuscular junction and actually physically view the consequences of losing these proteins," said Richmond. The conventional technique is to use gluteraldhyde fixation, which takes seconds or minutes to complete -- unlike the fraction of a second when using the high-pr...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...inds to the edge of the synthetic disc and forms a junction between natural and synthetic tissues. Then a clear layer of epithelial cells grow over the disc. 'Broadly interdisciplinary' Stanford's program to develop an artificial cornea is "broadly interdisciplinary," Frank says. Christopher Ta, an assi...

Cigarette smoking impedes tendon-to-bone healing

...e, they make proteins such as collagen to form the junction between tendon and bone. And in the rats exposed to nicotine, we saw lower cellular proliferation." The rats also made less type-I collagen and had different biomechanical properties in their shoulders following rotator cuff repair. Measuring prop...

UBC researchers find stroke death channel

...n cell membranes were disrupted at the site of gap junction hemichannels. Gap junctions are connections that a...n stroke occurs, hemichannels can form outside the junction and leak chemicals. The process drastically disrupts levels of critical brain cell ingredients such ...

First study to show how immune cells 'speak' to each other in vivo

... in laboratory rats. This immunologic synapse, or junction where signals are shuttled between two immune cells, has previously only been observed in cell cultures, in part because of the limitations of imaging and the rapid, touch-and-go nature of the communication itself. According to the researchers, thi...

Scientists reveal how deadly toxin hijacks cells

...stuttering. "I don't think there's a neuromuscular junction that hasn't been inhibited by injecting with botox A," says Chapman. Chapman and his team located the exact molecular gateway through which botox penetrates cells by gathering clues from earlier research that pointed to the potential importance of t...

Study provides insight into cellular defenses against genetic mutation

...final exon in the chain, as marked by an exon-exon junction complex (EJC), the cell concludes that the stop co... proteins, factors that come together at exon-exon junction complexes to drive NMD review. The three up-frameshift proteins work together to trigger decay once ...

UIC researchers show protein routes messages in nerve cells

...uestion because a synapse called the neuromuscular junction in the fly works much like synapses in human brain cells. "We can quickly mutate the flies," said Featherstone. "We looked among thousands of them for those without the glutamate receptors in the right place at the right time. Then we knew that the ...

The synapse is a shotgun

... the three-dimensional terrain of a synapse -- the junction between neurons which are critical for communication in the brain and nervous system. The "nano-map," which shows the tiny spines and valleys resolved at nanometer scale, or one-billionth of a meter, has already proven its worth in changing scientist...

Most common lung cancers may begin in newly discovered cells

...e oxygen and carbon dioxide are exchanged. At the junction of the bronchioles and alveoli, other groups have found evidence of cells that are resistant to damage and are involved in repair and maintenance of tissue. They have proposed that these junctions might be a stem cell niche. Bender Kim and her co-au...

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