Protein averts cell suicide but might contribute to cancer
...ll self-destruct. It's at this point when Dpo4 jumps in. It adds a base opposite the gap and then leaves, allowing the DNA-making machinery to bypass the damage and continue construction. The action averts cell suicide, but the gap ?and the stop-gap base ?might become a mutation that, in conjunctio...Researchers develop new method to help find deadly malaria parasite's Achilles heel
...n and prior to replication," he said. "What really jumps out of our paper is the large number of membrane protein interactions in Plasmodium that are absent in other organisms. While this is potentially good news for fighting malaria, we need to know much more before we start talking about which membrane-p...Genetic defenders protect crops from fungal disease
...ding on the mildew species), a second set of genes jumps into the fray. These genes, called EDS1, PAD4, and SAG101, work together in a complex inside the cell, and can signal infected cells to die. By sacrificing these fallen cells, the defense genes can spare healthy ones from infection. Somerville, Stei...Learning how SARS spikes its quarry
...is complex has to do with the fact that this virus jumps from animals to humans, laterally among humans, and in some cases from animals to humans but without subsequent human-to-human transmission," said Harrison. "And we know that those modes of transmission depend on specific mutations in the spike prote...'Jumping genes' contribute to the uniqueness of individual brains
...ormation in single brain cells. If enough of these jumps occur, they could allow individual brains to develop in distinctly different ways. "This mobility adds an element of variety and flexibility to neurons in a real Darwinian sense of randomness and selection," says Fred H. Gage, Professor and co-head ...