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Tag: "journey" at biology news

Scientists discover the cellular roots of graying hair

...em cellsgive rise to color-making melanocytes that journey to the bottom of thehair follicle: That is where they tint the keratinocytes with theperson’s characteristic hue.By studying mice at progressively older intervals, Fisher and hiscolleagues discovered that as the rodents aged and their hair beganturni...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...em cellsgive rise to color-making melanocytes that journey to the bottom of thehair follicle: That is where they tint the keratinocytes with theperson’s characteristic hue.By studying mice at progressively older intervals, Fisher and hiscolleagues discovered that as the rodents aged and their hair beganturni...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...em cellsgive rise to color-making melanocytes that journey to the bottom of thehair follicle: That is where they tint the keratinocytes with theperson’s characteristic hue.By studying mice at progressively older intervals, Fisher and hiscolleagues discovered that as the rodents aged and their hair beganturni...

Nano-Probes Allow an Inside Look at Cell Nuclei

...rradiation. They have already visualized the dots' journey from the area surrounding the nucleus to inside the nucleus, a feat that opens the door for real-time observations of nuclear trafficking mechanisms. They also hope to target other cellular organelles besides the nucleus, such as mitochondria and Gol...

UCLA scientists transform HIV into cancer-seeking missile

... fireflies glow to the virus in order to track its journey from the bloodstream to new tumors in the animals' lungs. "For the past 20 years, gene therapy has been hampered by the lack of a good carrier for therapeutic genes that can travel through the blood and aim itself at a precise location, thereby mini...

Double triumph in stem cell quest

... and sex. "This is an enormous stride in the long journey to determine whether nuclear-transfer-derived human embryonic stem cells might be eventually suitable for transplantation medicine," says Gerald Schatten of the University of Pittsburgh School of Medicine, the only non-Korean member of the team. But...

To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter

...eggs. And the tiny male has avoided the harrowing journey taken by most salmon to the ocean and back, bypassing hazards such as dams, sharks and fishermen. "In some species, all or a fraction of the individuals in some populations do not migrate to sea at all," he says. "These fish sacrifice the growing op...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...ol was increased. This is an important step in our journey to ultimately eliminate the suffering and death due to cancer.?/p> A total of 722 women with recurrent or metastatic breast cancer who had not previously received systemic chemotherapy for their recurrent or metastatic disease were enrolled in th...

Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves

... along the axon, and in the course of this arduous journey can easily lose their phosphorus en route. Dr. Michael Fainzilber and graduate students Eran Perlson and Shlomit Hanz of the Weizmann Institute's Biological Chemistry Department found that the Erk messengers, together with their phosphorus message, ...

Searching the depths of the straits of Florida for disease cures

...ong trip that deters most. Divers who do make the journey are fond of Cay Sal because of its spectacular reefs, extensive cave systems, and abundant sea life, including the elusive whale shark. Harbor Branch scientists are attracted most to its steep topography between about 300 and 3,000 feet, which sugges...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...new oral compound that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream to be used by the body, according to research from the University of Southern California School of Pharmacy. This technology may allow for oral administration o...

Study shows how retinoic acid enters a cell's nucleus

...ucleus requires passage through water, a difficult journey for a hydrophobic compound. For RA to rapidly enter a cell's nucleus, it must catch a ride on a water-soluble protein called cellular retinoic acid-binding protein type II (CRABP-II). This protein was discovered over two decades ago, but until recent...

Divergent life history shapes gene expression in brains of salmon

...lmon that will eventually undertake the well-known journey from their river birthplaces to oceans ? and then migrate heroically back upstream one to three years later to spawn ? and males of the same age known as "sneakers" that mature at greatly reduced size without leaving freshwater. "The finding that hu...

Team of international scientists departs today to discover the unknown in China's Himalayan region

...t: Mission Himalayas" is a scientific and cultural journey to explore one of the planet's richest and most biologically diverse regions. The expedition begins today with a month-long exploration in China where scientists, conservationists, Imagineers from Disney and filmmakers from Discovery Networks will jo...

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds

...confident that her technique will be a part of the journey towards a cure for the disease and for other diseases such as hemophilia and the skin disease, epidermolysis bullosa. Early trials using her approach have looked promising in animal models of both of these diseases. "I think our approach has a lot o...

FSU biologists describe key role of signal-transcribing gene during cell cycle

...h and Cut," said Deng. The researchers traced the journey of transmissions originating from Notch ?? which carries information gleaned from other cells ?? following the signals down the Notch pathway as Cut linked them to the control of cell proliferation in the egg chambers, which they observed at differen...

New methods offer insight into regulatory DNA

...al Genetics, Wellcome Trust Sanger Institute. "The journey for our biomedical research is from DNA sequence to individual people and individual disease. The HapMap is a bridge from sequence data to the differences in individuals." The project focused on three regions of the human genome. The first, called ...

USC researchers track down the stem cells that create feathers

... time, signifying the initial step in a scientific journey that may ultimately shed light on human organ regeneration. The research, published in the December 15 issue of the journal Nature, was performed by a group of prominent stem-cell researchers from the Keck School of Medicine of the University of Sou...

Portable cocaine sensor developed at UC Santa Barbara

... really the results that were so important but the journey and the process." ...

Malaria parasites develop in lymph nodes

...n lymph nodes close to the site of the bite. Their journey seemed to stop there, as the malaria parasites almost never appeared in lymph nodes farther away. Within about four hours of the mosquito bite, many of the lymph-node parasites appeared degraded. They were also seen interacting with key mammalian im...

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