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Tag: "journal" at biology news

Researchers rein in regulatory RNAs

...r findings are published in the April issue of the journal Genome Research. Sense-antisense transcripts, or SATs, are pairs of RNA molecules generated from opposite DNA strands at the same locus. The number of SATs identified in the past several years has grown substantially, and they are now believed to co...

UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System

...s. Published in the January 28, 2005 issue of the journal Science, the study found that the phosphatases, called small carboxyl-terminal domain phosphatases (SCPs) are expressed in almost all tissues of the body. In their “on?position, the phosphatases prevent neuronal genes from being expressed in areas of...

New drug shows promise as powerful anticancer agent

Research published in the March issue of the journal Cancer Cell describes a small molecule inhibitor of polo-like kinase1 (Plk1) that could lead to a new avenue for targeted cancer therapy. The compound, ON01910, is a potent inhibitor of human tumors in a mouse model system and has low toxicity. The r...

Alzheimer's cognitive decline slowed

...ublished in the April 24, 2005 online issue of the journal Nature Medicine by researchers at the University of California, San Diego (UCSD) School of Medicine. PET scans demonstrated an increase in the brain's use of glucose, an indication of increased brain activity, while mental-status tests showed a slow...

Survey finds silver contamination in North Pacific waters

...eochemistry, Geophysics, Geosystems, an electronic journal published by the American Geophysical Union and the Geochemical Society. Ranville found silver concentrations as high as 1.2 parts per trillion in samples of North Pacific surface waters taken during the cruise. This is about 50 times higher than ba...

Strongest proof yet found for prion hypothesis

...he disease. In a paper scheduled to appear in the journal Cell on April 21, the UTMB researchers describe the use of a method they developed called "protein misfolding cyclic amplification" (PMCA) to vastly accelerate the activity of a small number of prions taken from infected hamsters and placed in test t...

Navigating an integrated yeast network

...another. New research published in the Open Access journal Journal of Biology shows that such maps can also reveal cryptic interactions and enable accurate predictions about interactions that haven't been observed experimentally. A living cell contains thousands of proteins, genes and macromolecules, enmesh...

Researchers uncover sequence of major rice pathogen

...sea genome, published in the April 21 issue of the journal Nature. It is estimated that rice blast, the leading cause of rice loss, is responsible each year for killing enough rice to feed 60 million people worldwide. In the Nature paper, Dean and his co-authors shed some light on the adaptations required ...

Researchers make gains in understanding antibiotic resistance

...d its findings in the April 22, 2005, issue of the journal Cell. Steitz and his colleagues studied the struc...d, for example, recent statistics published in the journal Nature, stating that hospitals in the United States see some two million cases of antibiotic-resista...

Scientists identify genetic pathways essential to RNA interference

...fight human disease. The report will appear in the journal Science and is receiving early online release on the Science Express website at http://www.sciencexpress.org. "The gene activation produced by RNAi is exquisitely specific, which gives it enormous potential for therapeutic application," says Gary Ru...

Brain-mapping technique aids understanding of sleep, wakefulness

... online and appearing in the April 21 issue of the journal Neuron, shed light on the complex mechanisms involved in sleep regulation and may help to explain why once a person wakes up and moves around, he tends to stay awake. "We all know subjectively and objectively that there is a very strong force regula...

Canadian youth 4th highest in international obesity study

...ich appears in the May issue of Obesity Reviews, a journal of the International Association for the Study of Obesity. "Increasing physical activity participation and decreasing television viewing should be the focus of strategies aimed at preventing and treating overweight and obesity in youth." The study i...

Sickle cell and protection against malaria

... this month's issue of the freely available online journal PLoS Medicine, Dr. Thomas N. Williams and colleagues from Kilifi, Kenya, show that the protection against malaria given by carrying the gene for sickle cell haemoglobin may involve the immune system. Studying a group of children and adults in the Kil...

Small species back-up giant marsupial climate change extinction claim

...gion of south-eastern Queensland. Reported in the journal Memoirs of the Queensland Museum tomorrow (Tuesday 31 May) they found smaller species, dependent on a wetter environment, had also disappeared. By systematically analysing a 10 metre deep section of creek bed, the team uncovered 44 species, ranging ...

Defenseless plants arm themselves with metals

...eported in today's (Friday, March 11) issue of the journal Plant Physiology, shed new light on the evolution of these plants and may have implications for the development of crops that may one day remove metal and other contaminants from the environment. "Our goal is to find the high-level regulator - the o...

Genetic defects give the immune system the green light to attack the pancreas

...rmed with these findings published March 22 in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients. “The significance of this study is that we found the chromosomal regions involved and can now zero in on the precise genes,?said Diane Ma...

Medical whistleblowers speak out

...published in the open access international medical journal PLoS Medicine. One of the lessons, says Lenzer, is that "ties between drug regulators and industry may influence new drug approval." Graham said at the roundtable that the FDA was in "a collaborative relationship" with industry, and that the FDA gets...

Study reveals new technique for fingerprinting environmental samples

... study, published in the April 22nd edition of the journal Science positions large-scale genome sequencing to accelerate advances in environmental sciences akin to the contributions DNA sequencing has made to biomedical sciences. "These DNA sequence fingerprints can be used to provide highly accurate assess...

Used in a new way, RNA interference permanently silences key breast cancer gene

...he study appeared in the April 1 2005 issue of the journal Cancer Research. "The technique is also providing some valuable insights into the role of STAT3 and its downstream targets," adds Arlinghaus, who also will discuss the work in a mini symposium at the AACR meeting. RNAi has been employed as a labora...

Researchers unlock mechanism creating jigsaw puzzle-like plant cells

... findings were published in today's edition of the journal Cell. Zhenbiao Yang, a professor of plant cell biology at the UCR's Center for Plant Cell Biology and Institute for Integrative Genome Biology, worked with a team of researchers which included Geoffrey Wasteneys from the University of British Columb...

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