New technique could alter field of mouse genetics
.... A reliable gene-transposing tool could make that job much easier and quicker. Xu and his colleagues at Fudan University in Shanghai, China, began their studies with a transposon called piggyBac. With the help of a partner enzyme, piggyBac can reliably and efficiently insert itself into the genomes of ...Toxic flood lifts lid on common urban pollution problem
...ssor at Louisiana State University before taking a job at UF this summer. "What we see in New Orleans is that when you put a lot of water in contact with the urban environment, all the potential contaminants that stayed around in that environment are now back in the water - definitely, to our horror," S...Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
...er that your body becomes wiser in how it does its job and less wasteful in energy usage." Coyle added later: "There's no doubt that Armstrong started with a strong genetic makeup, but he maximized his abilities and got where his is through dedication and hard training." Source The study, entitled "Im...Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses
...e. "NS5 prevents interferon from doing its sentry job and allows the virus to take over cells," says Dr. Bloom. "This is the first definitive study that dissects where the failure occurs in the signaling pathway, and then identifies some of the interacting partners in the cell and virus." Prior to this ...Newly discovered genetic disease sheds light on body's water balance
...o fit a classic pattern, but actually doesn't, our job as physician scientists is to recognize the discrepancy and get to the bottom of the situation." First, Gitelman and his colleagues worked to find an innovative treatment for the two young patients. "When adults retain too much water we can treat th...Atmosphere may cleanse itself better than previously thought
...it means is that we need to do a much more careful job with our measurements in order to accurately account for all the reactive chemicals present in the air." Francisco said he hopes the study also would encourage other refinements to atmospheric models. "Models are only as good as the information we ...Touching Molecules With Your Bare Hands
...ough it lacks the amino acid element that does the job for EBV. Future studies will have to determine the responsible MHV-68 epitope and the mechanisms that engineer immune avoidance. Since a majority of epitopes that killer T cells recognize come from aborted translation events, it may be that evasive a...How A Latent Virus Eludes Immune Defenses
...ough it lacks the amino acid element that does the job for EBV. Future studies will have to determine the responsible MHV-68 epitope and the mechanisms that engineer immune avoidance. Since a majority of epitopes that killer T cells recognize come from aborted translation events, it may be that evasive a...Red delicious, Northern Spy apples have most antioxidants, chemists find
Some apples might do a better job of keeping the doctor away than others, according to Canadian researchers who analyzed eight popular varieties of the fruit. Red Delicious, Northern Spy and Ida Red, they say, pack a greater wallop of disease-fighting antioxidants than other apples s...The evolutionary triumph of flower power
... and birds ?no longer find them attractive. So the job of propagating the species depends mainly on us. A recent article in the journal "Evolutionary Psychology" by McGuire; Jeannette Haviland-Jones, a professor of psychology at Rutgers, The State University of New Jersey; and others, states that in spi...Turning viruses into allies against cancer
...nulocyte macrophage colon stimulating factor). Its job is to induce an immune response to any surviving cancer cells released during the initial viral attack, essentially preventing the spread of these cells to other parts of the body. "This aims to treat metastatic disease and reduce tumor recurrence,"...Medical whistleblowers speak out
...rights lawsuit on November 22 2002 "to preserve my job and my right to speak out." Jones explained that he had investigated an account into which pharmaceutical companies were paying money that was being accessed by state officials. These officials "were given unrestricted educational grants that were d...GeneNotes - A novel information management software for biologists
...s of database with tons of information... and your job is to make sense of this puzzle in a biologically meaningfull way. Applications are being developped to make it all easier, leaving the fun part : biology! GeneNotes is one of them; I didn't have time to try it yet, but it seems like it could help. N...Wisconsin researchers identify sleep gene
... produces this effect. Nevertheless, Shaker's main job in flies-and in its equivalent in humans--is to control the excitability of cell membranes. Genetic analysis of the mns flies, conducted by Daniel Bushey, a post-doctoral fellow working with the Tononi team, revealed that their Shaker genes containe...Antibiotic might fight HIV-induced neurological problems
... "In people, antiretroviral treatments do a great job of controlling HIV in blood, but most of the drugs don't cross the blood-brain barrier very well," says Christine Zink, D.V.M., Ph.D., professor of comparative medicine at the Johns Hopkins University School of Medicine. "As a result, even though the...Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
...patients. "For 20 years it has been the chemist's job to develop agents that can be used to enhance MRI ... Mellon. "Now, with our approach, we have put this job into the hands of the molecular biologist. Using off-the-shelf molecular biology tools we can now en...Bird Brains Show How Trial and Error May Contribute to Learning
...ense that one part of the brain has as part of its job introducing that kind of variability." Kao began with an experiment to stimulate the region of the forebrain called LMAN (lateral magnocellular nucleus of the anterior nidopallium). In the avian brain, LMAN receives input about complex movements fro...New RNA polymerase discovered in plants
...d for expression of biological traits. It does its job by copying a template of DNA genetic information in order to make RNAs that encode proteins or that function directly in the cell. Biologists have studied three kinds of RNA polymerase for decades in organisms ranging from brewer's yeast to humans. ...Taking Aim With Nanoparticle PEBBLEs
...t nanoparticles such as PEBBLEs can do a fantastic job for therapy, diagnostics and a combination of the two." Kopelman's collaborators on the work he will discuss in San Diego are Martin Philbert, professor of toxicology and Associate Dean for Research in the School of Public Health; Brian Ross, a prof......olecules in prescribed sequences and patterns. One job of Ubp10, as identified in this study, is to remove ubiquitin from certain histones where ubiquitin is associated with gene activation and to maintain low levels of the ubiquitin molecule at those sites. Interestingly, Ubp10 appears to work similarl...