Mechanism for memory revealed in neurons of electric fish
...rs when the fish are close to each other. They can jam each other's electrical signals. In response, one of the fish will jump to a higher frequency to avoid the jamming signal, emitting more electrical pulses per second than its neighbor. Oestreich and Zakon found that once the jamming avoidance has s...'Computer-chemistry' yields new insight into a puzzle of cell division
...lopment of various cancers. Anti-cancer drugs that jam the enzyme, preventing its docking with the kinase, could halt cell over proliferation to treat such cancers. However, developing such drugs has been hampered by lack of detailed understanding of how the Cdc25s fit with their associated kinases. "T...Researchers make gains in understanding antibiotic resistance
...iotics that, while chemically quite different, all jam the activity of the protein-making factory in bacteria in much the same way. They studied the MLSBK antibiotics, an acronym for a group of antibiotics which include macrolides, lincosamides, streptogramin B and ketolides. MLSBK antibiotics work by bi...Protein offers way to stop microscopic parasites in their tracks
... spots have to be cut off at the back or they will jam the belt, greatly reducing the parasite's ability to move and thereby infect a host. A postdoctoral researcher in Sibley's lab, Fabien Brossier, Ph.D., decided to try to use the recently completed Toxoplasma genome to search for the protein that let......f the nerve cells. In a vicious cycle, the traffic jam also could increase production of an abnormal protein that clogs neurons, leading to their failure and eventual death. The researchers said their findings could provide information that might be used to develop drugs to preserve the molecular transp...