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Tag: "itself" at biology news

Antibodies from plants protect against anthrax

...ainst anthrax. Then genes that encode the antibody itself were inserted into a bacterium that transfers the gene into the plant cells. "The plant makes the antibody for you in a few days," says Baillie. The antibodies were then purified from leaves harvested from the infected plants and tested for their ab...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...n that genetic events outside the epithelial layer itself have a profound effect on tumor initiation. Thus it appears likely that this study will foster additional research into other mesenchymal genetic modifiers, and into potential therapeutic approaches that affect the signaling between the two cell laye...

NJIT Presidential Award winner takes stem cell research another step

... maintains tissues and organs, and which can renew itself through cell division. Stem cells are harvested from bone marrow, umbilical cords, the brain and spinal cord and other tissues. Adult stem cells also have a unique trait that lends them their magic: Under the right conditions, or given the proper sig...

New methods of gene delivery using lasers

... mechanism causes the membrane of the cell to heal itself thus appearing to suffer no long-lasting damage. After inserting the genes, the team grew the cells, which appeared to remain healthy and multiplied normally. The presence of the inserted gene in the multiplied cells was then confirmed by observing t...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

... Inside the cell, the DNA encoded VEGF-2 expresses itself which in turn stimulates the growth of new blood vessels by promoting the proliferation of endothelial cells in the heart. New blood vessels are required to provide oxygen-carrying blood to heart muscles to compensate for the blocked heart arteries....

Artifical cornea lets woman blind 20 years see

...ferent," he said. It isn't the cost of the device itself that is the problem, according to Dohlman. Rather, it is the prohibitive cost of the frequent post-operative visits, the travel required, the medications and contact lenses used in follow up with the patients. For now, however, the devices are becom...

How the environment could be damaging men's reproductive health

...e the sex chromosome ratio in sperm is worrying in itself and requires more attention from scientists and the public," said Prof Giwercman. The second study by researchers from Denmark, Lithuania and Finland[2] suggests that a higher than expected prevalence of cryptorchidism (undescended testes) in Lithua...

Drug-resistant bacteria on poultry products differ by brand

...esistant to antibiotics. Not only can the bacteria itself cause illnesses such as diarrhea in humans, but fluoroquinolones are some of the most important drugs used to treat a variety of infections, including those caused by Campylobacter. The widespread presence of this drug-resistant form of the bacteria ...

Discovery Promises Simpler Therapy for Sickle Cell Disease

... said. Current therapies fail to treat the disease itself and are instead geared toward minimizing pain and preventing infection, he added. In patients who become anemic, blood transfusions replenish the red blood cell supply in the body. The team further found that differences among patients in their abil...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

...m for stimulating protein degradation. Cholesterol itself had no such effect on reductase, even at much greater concentrations, they found. "The current results demonstrate a direct role for lanosterol as a selective, physiologic regulator of reductase ubiquitination and degradation," said DeBose-Boyd. Tha...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...ing of brain tissue. The abnormally folded protein itself appears to act as an infectious agent, transmitting disease without a DNA or RNA genome such as in a virus. Although disease prions seem to infect normal prions by binding to them and forcing them to take on the abnormal configuration, researchers re...

Scientists discover how plants disarm the toxic effects of excessive sunlight

...to sense the presence of singlet oxygen and defend itself from this toxic substance. He notes that the response mechanism is likely highly conserved across species from microbes to plants and humans - and therefore very applicable to other fields of study. For example, too much sunlight can actually be har...

Gene Therapy Cures Inherited Liver Disease In Rats

... genes in this area of the cell. The viral vector itself is important because it has no long term effect. It does not become part of the genetic machinery of the cell and poses no risk of causing cancer, said Lee. "This approach would be applicable to many diseases where you are trying to put something ba...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...ere. If it can't exist in ticks, it can't maintain itself in nature and hence can't infect animals or humans." UT Southwestern molecular microbiology graduate student Andrew Revel, a lead author of the study, found the bptA gene by screening a number of candidate genes he thought might be affecting the sur...

New insight into regulation of blood stem cells

...ch can either "self-renew" and make more copies of itself or differentiate into either red blood cells, various types of white blood cells, or platelets. The genes that control proliferation and differentiation have been difficult to study using traditional gene disruption methods because loss of genes thou...

Birds brains reveal source of songs

...g. These results suggested that the AFP circuitry itself causes the juvenile bird's experimentation with various sounds and sequences, and that such explorations are essential to learning songs. Deactivating the AFP after a bird had already learned the correct song had no affect on its continued proficienc...

Scientists identify genetic pathways essential to RNA interference

...s in plants or animals. They used the RNAi process itself to find new genes that participate in the gene-silencing mechanism, which someday may help to fight human disease. The report will appear in the journal Science and is receiving early online release on the Science Express website at http://www.scienc...

Brain-mapping technique aids understanding of sleep, wakefulness

... nontoxic fragment of the tetanus toxin, transfers itself from one neuron in retrograde fashion to neurons "upstream" -- those from which the tracer-producing neuron receives signals. Researchers then track the tracer to map the upstream neurons. Dr. Yanagisawa and his colleagues are the first to apply the...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

... widespread testing, she said. The cost of testing itself would be relatively low. Although lysosomal storage diseases are rare ?fewer than 5,000 births combined out of 4 million per year in the U.S. ?they are best treated if patients are diagnosed and treated in early infancy, said Kurtzberg. In fact, tra...

Medical whistleblowers speak out

...y agencies, and medical journals - can disentangle itself from the influence of the pharmaceutical industry." ...

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