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Tag: "its" at biology news

New Mixing Method for Microchip-Sized Labs

...east cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway and otherpathways, a lot of feed-forward and feedback loops,?says Mills. “But Iand others believe there are central nodes between these intersectingci...

UCSD discovery may help extend life of natural pesticide

...r for the toxin that allows the toxin to recognize its "victim"--a roundworm or an insect. This paper als...dworms, but not to vertebrates, which accounts for its popularity as a pesticide," explained Aroian, who led the team. "But the development of insect resis...

The very unexpected life and death of a leukemic cell

...er is made using a form of hydrogen that has twice its normal mass, making the water molecule "heavier" t...to glucose and the tagged glucose eventually makes its way into the cell's DNA. Researchers gave 19 individuals with CLL a small dose of heavy water every...

Study of genomic DNA leads to new advances in cancer diagnostics

...s alike know that how a cancer cell interacts with its microenvironment is important for cancer progressi...eton, the internal scaffolding that gives the cell its shape, in this process. Changes to the ECM and cytoskeleton are critical to migration of a cancer ce...

New RNA polymerase discovered in plants

...s and for expression of biological traits. It does its job by copying a template of DNA genetic informati... of Pol IV to unravel. "We know what happens when its gone, but not how it behaves, at this point," he said. "We don't know its template, or what kind of ...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...on in the APC gene, mutations in the Foxl1 gene or its targets may dramatically increase the likelihood that the second normal copy of the APC gene is lost or mutated, leading to the initiation of tumor formation. This study sets a new paradigm for gastrointestinal tumorigenesis, in that genetic events ...

Bird Brains Show How Trial and Error May Contribute to Learning

...ebra finch knows only one scratchy tune learned in its youth, which it performs repeatedly and intensely ...es sense that one part of the brain has as part of its job introducing that kind of variability." Kao began with an experiment to stimulate the region of ...

Agilent Technologies releases automated literature search tool for biology researchers

...ilent Laboratories is using the plug-in as part of its collaborations with two other organizations on systems biology projects: the Stanford University School of Medicine on auto-immune diabetes; and the Translational Genomics Research Institute (TGen) on melanoma, autism and pancreatic cancer. Labs rese...

The Bacteria's guide to survival

...it would be in a bacterium's interest to help keep its host alive. And bacteria appear to do this with the help of their pili. ### Citation: Howie HL, Glogauer M, So M (2005) The Neisseria gonorrhoeae type IV pilus stimulates mechanosensitive pathways and cytoprotection through a pilT-dependent mechani...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

...e catalysts on nanoporous materials synthesized by its wet-chemical technique. This renders the catalysts in a solid form, enabling them to be easily recovered and reused through simple filtering or centrifuging processes. This allows for the more efficient synthesis of a wide variety of pharmaceuticals....

RNA project to create language for scientists worldwide

...iding $500,000 for the five-year project as one of its Research Coordination Networks, whose goals are to "encourage and foster interaction among scientists" and to facilitate "innovative ideas for implementing novel networking strategies." As principal investigator, Leontis will serve as coordinator of...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...sveld's group previously identified TEL2 and noted its similarity to TEL1, which prompted them to investigate whether TEL2 also played a role in leukemia. In the MCB study, the investigators discovered that, unlike TEL1, TEL2 promotes cell multiplication, playing an indirect role in the development of B ...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

... and more practically, how a pathogen differs from its human host, or a diseased cell differs from it healthy counterpart at the most informative level of detail." For centuries, systematic comparisons of animal, plant, and microbial species was based on painstaking measurements of anatomic features. Be...

South America's vast pantanal wetland may become next everglades, UNU experts warn

...pressure from economic development, alterations of its water courses and conversion to other land uses." ...at increasing the contribution of the Pantanal and its catchment area to the economy. "This economic development and consequent population growth, pose a n...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

... Elgar and colleagues chose the zebrafish, because its transparent embryo is ideal for observing developmental events. They injected individual CNEs into embryos, along with a green fluorescent protein (GFP) reporter. By day two of development, 23 out of 25 CNEs injected had upregulated GFP expression, i...

Scientists discover that host cell lipids facilitate bacterial movement

...ria monocytogenes invades the body, it commandeers its host cell's actin cytoskeleton to invade other cel...ia is able to attract host cell membrane lipids to its surface and these membrane lipids facilitate the ability of the bacterium to move within cells. This...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

... at work in the human mouth is very different from its behavior when it’s vacationing in a Petri dish. “An organism growing in a lab isn’t causing disease,?Lamont said. “It’s an organism that’s in your gums, your lungs, your heart valves, your arteries causing disease.?/p> The next step will be to e...

Scientists solve structure of key protein in innate immune response

...ng crucial insights into how the receptor binds to its ligands. "Our structure shows that CD14 has a large hydrophobic pocket near its amino terminus," says Dr. Lee. "We propose that this pocket is the main binding site for LPS because...

Key Trigger Of Opioid Withdrawal Symptoms Found

... the molecular ammunition that one neuron fires at its neighbor to trigger a nerve impulse in the neighbo...ey trigger nerve impulse, to reload the neuron for its next signaling burst. Bagley and her colleagues also discovered that a molecular switch called prot...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...December 31, 2003 and other SEC reports, including its Quarterly Reports on Form 10-Q for subsequent quarterly periods. Affymetrix expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Aff...

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