New SARS Protein Linked To Important Cell Doorway
... and death. When the SARS virus first jumped from its still unknown animal reservoir to humans in late 2... efforts revealed orf7a, a SARS protein that makes its home in a structure cells use to modify proteins destined for transport to the cell surface. Researc...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...o method. Adistinguishing aspect of Moleculizer is its ability to generate proteincomplexes and reactions as they are needed, as opposed to generatingall potential complexes and reactions all at once, a task that requirestremendous computer resources beyond the scope of most research labs. "Moleculizeri...Jumping gene helps explain immune system's abilities
... bacteria.Although this loop distances Hermes from its well-studied cousins, theHermes protein still has ...theoverall sequence is quite different."Because of its similarities both to V(D)J recombination and to otherfamilies of jumping genes, Hermes is the first ...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
... bacteria.Although this loop distances Hermes from its well-studied cousins, theHermes protein still has ...theoverall sequence is quite different."Because of its similarities both to V(D)J recombination and to otherfamilies of jumping genes, Hermes is the first ...Scientists document complex genomic events leading to the birth of new genes
...discrete cytoplasmic locations, thereby confirming its functional divergence from RanBP2. Identifying and characterizing genes that are responsible for primate or human distinctiveness has been a major challenge to scientists. However, this work by Bork and his colleagues should further enable studies f...New therapy for HIV/AIDS eliminates needles and excessive toxicity
... bacteria.Although this loop distances Hermes from its well-studied cousins, theHermes protein still has ...theoverall sequence is quite different."Because of its similarities both to V(D)J recombination and to otherfamilies of jumping genes, Hermes is the first ...Nano-Probes Allow an Inside Look at Cell Nuclei
Nanotechnology may be in its infancy, but biologists may soon use it to watch the inner workings of a living cell like never before. Scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Lawrence Livermore National Laboratory have...DNA Recombination and Repair—A New Twist to RecA Function
...er’s 5' end, while ATP hydrolysis occurs all along its length. Under their experimental conditions, the ...s ATP in synchrony with the sixth RecA molecule to its left and the sixth RecA molecule to its right. The authors note that there are approximately six Re...Gene sequencing explains bioremediation 'bug'
... bacteria.Although this loop distances Hermes from its well-studied cousins, theHermes protein still has ...theoverall sequence is quite different."Because of its similarities both to V(D)J recombination and to otherfamilies of jumping genes, Hermes is the first ...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...ll recognizes and attacks depends on the makeup of its receptor, which is constructed of protein building...esearch Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Fo...Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed
...ce in that area has lost only 200 to 400 meters of its thickness in the last 20,000 years, said Edwin Wad...nce rested on the bottom of the bay all the way to its "grounding line" at the continental margin in the Ross Sea. However, that ice has retreated substant...UCLA scientists transform HIV into cancer-seeking missile
...akes fireflies glow to the virus in order to track its journey from the bloodstream to new tumors in the animals' lungs. "For the past 20 years, gene therapy has been hampered by the lack of a good carrier for therapeutic genes that can travel through the blood and aim itself at a precise location, ther...New Breast Cancer Test Could Save Lives
...w technology and the benefits that might come from its use.?/p> This world-leading research project is funded by the United Bristol Healthcare Trust (UBHT), the University of Bristol’s enterprise initiative and the Sulis Seedcorn fund, which recently awarded over £100,000 of venture capital to the pr...The BIOS Initiative - open source biotechnology is born
...s, CAMBIA is also releasing new functionalities in its highly successful Patent Lens, which includes the ...n patents in the life sciences. CAMBIA has flagged its intent to expand its scope beyond the life sciences to include all patents in many countries, to cre...Beyond lithium for bipolar disorder
...Americans with bipolar disorder, it is not without its downside. People on the drug may develop hypothyro...r a protein that is an "orphan receptor"--that is, its cellular function in sensing external chemical signals is unknown. The researchers also found that ...Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
...sity of California at San Diego and co-director of its Mitochondrial and Metabolic Disease Center, "What's attractive about this novel optical method for identifying cancer cells is it's a very rapid and general method that potentially can be applied to cancer cells from solid tumors as well as hematolog...PANTHER Protein Classification System Database 5.0
...ation analysis with graphical output. Best ofall, its available freely . A paper describing the Database is available freely in the Nucleic acids research Journal . AppliedBiosystems (NYSE:ABI), an Applera Corporation business, today announcedthe latest release of the PANTHER?system database of protei...Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway
...east cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway and otherpathways, a lot of feed-forward and feedback loops,?says Mills. “But Iand others believe there are central nodes between these intersectingci...Genetic Variation Visualization - From EMBL
...east cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway and otherpathways, a lot of feed-forward and feedback loops,?says Mills. “But Iand others believe there are central nodes between these intersectingci...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...Ras. This methyl tag enables Ras to be directed to its final destination in the cell, from where it can s...David Gooden to synthesize the molecule and verify its chemical structure. A search of the chemical literature turned up no previous description of the che...