Transport System Smuggles Medicines Into Brain
...and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is that the pigment is found only in the bird's feathers and nowhere else in the body of the bird, indicating that parrots manufact...Scientists develop new color-coded test for protein folding
...sive sensor for determining when a protein changes its conformation," said study co-author Richard N. Zare, the Marguerite Blake Wilbur Professor in Natural Science in Stanford's Department of Chemistry. According to Zare, the new sensor may eventually provide biomedical researchers a fast, affordable me...Placenta Is A Rich Source Of Blood Stem Cells
...erprise based at a pediatric medical center, where its discoveries have benefited both children and adults for over 136 years. More than 500 scientists, including eight members of the National Academy of Sciences, nine members of the Institute of Medicine and 10 members of the Howard Hughes Medical Insti...Probing The Promise And Perils Of Nanoparticles
For all its promise, the prospect of using nanoparticles in biomedical applications and consumer products has raised concerns about possible harmful effects of the miniscule materials. Scientists at the University of Michigan are addressing those concerns by inv...Study shows nanoshells ideal as chemical nanosensors
...limitation in the use of Raman scattering has been its extremely weaksensitivity. While it was discovered almost three decades ago thatroughened metallic surfaces could enhance Raman scattering signals byfactors of 1 million, this "surface-enhancement" effect has beendifficult to control, predict, and re...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...d VEE, forVenezuelan equine encephalitis, which in its natural form can causedisease in horses.Researchers at AlphaVax, Inc., a privately held biotechnology companyin Research Triangle Park, N.C., have deleted certain genes from theVEE virus, thereby making it impossible for the vector version of virusto...Highly adaptable genome in gut bacterium key to intestinal health
...human gut adaptively shifts more than a quarter of its genes into high gear when its host's diet changes from sugar to complex carbohydrates. This adaptive mechanism not only allows th...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...d VEE, forVenezuelan equine encephalitis, which in its natural form can causedisease in horses.Researchers at AlphaVax, Inc., a privately held biotechnology companyin Research Triangle Park, N.C., have deleted certain genes from theVEE virus, thereby making it impossible for the vector version of virusto...Same mutation aided evolution in many fish species, Stanford study finds
...ew conditions, or if evolution has other tricks up its sleeve to push organisms towards an optimal form for their environment. Other Stanford researchers who participated in the study include graduate students Pamela Colosimo, PhD, first author on the study, and Kim Hosemann; technician Sarita Balabhadr......h century’s greatest scientists, Francis Crick, on its Profiles in Science Web site. Don't miss Crick's sketch of the DNA double helix . This latest collection on Profiles in Science represents a close collaboration between the National Library of Medicine and the Wellcome Library for the History an...Gene Therapy For Parkinson's Disease Moves Forward In Animals
...cribes one strategy to halt Parkinson's disease at its onset and another strategy to treat the devastatin...de effects that occur when treating the disease in its later stages. By inserting corrective genes into the brain, scientists studying small monkeys calle...Researchers trace evolution to relatively simple genetic changes
...ppens to the ectodysplasin signaling molecule when its gene is mutated in humans, and in fish, shows a major difference. The human protein suffers "a huge amount of molecular lesions, including deletions, mutations, many types of lesions that would inactivate the protein," Kingsley said. But in contrast...Scientists reveal molecular secrets of the malaria parasite
...larity among genes on P. falciparumchromosomes and its rodent-malaria counterparts."The paper is significant on many levels, including the integration ofdraft genome sequence data with microarray and protein expressiondata," says Carlton. "This project also shows the power ofcollaboration between interna...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...ppens to the ectodysplasin signaling molecule when its gene is mutated in humans, and in fish, shows a major difference. The human protein suffers "a huge amount of molecular lesions, including deletions, mutations, many types of lesions that would inactivate the protein," Kingsley said. But in contrast...Studies reveal methods viruses use to sidestep immune system
...e virus adapts and comes up with a new function of its own to counteract our defenses." Further defining...nds the virus genetic material. RIG-I then changes its shape, which sends a cascade of signals to other proteins to activate a transcription factor called ...Development of portable infectious disease detector
...detectors." The collaboration's goal is to produce its firstportable HIV monitor within two years. In addition to such "point ofcare" devices, Wikswo and Pyle are joining forces to develop"high-throughput" screening systems that can determine the biologicalactivity of large numbers of compounds with extr...Researchers add new tool to tumor-treatment arsenal
.... Used in organ transplant patients, rapamycin and its derivatives have shown promising anti-tumor activity in phase I and II clinical trials. RAD001 lowers the amount of DNA-damaging agent needed by blocking p53's DNA-repair function, automatically killing the cancer cells when agents like cisplatin ar...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
... from their bodies is equally important to prevent its toxic buildup in tissues. "Even in our own case, o...h released but also the concentration of oxygen in its trachea, the series of tubes that carry air directly to cells for gas exchange. Using a respirometer...Scientists discover unique microbe in California's largest lake
...aryochloris is unique because it is able to liveon its own," says UO biology professor Michelle Wood. She...rmof Acaryochloris. Blankenship and Olson compared its pigments withthose of A. marina, one of the symbiotic species."Chlorophyll d is a pigment that is in......a condom) is popular with the American government, its application in other parts of the world may not have the impact required. In the face of this global catastrophe, the epidemic in the United Kingdom seems both small and parochial, say the authors. Nevertheless, the latest figures show a 20% increas...