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Tag: "its" at biology news

Breakthrough Microarray-based Technology for the Study of Cancer

...nt'sbreakthrough is founded on the modification of its gene-expressionprofiling microarray technology to improve its utility for DNA analysisapplications. This new platform provides high sensitivity, enabling CGHresea...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...ded. Without messenger RNA, agene cannot translate its genetic code into proteins that carry out itsinten...ted in place ofCth2 in yeast, they actually assume its function in yeast cells, saidThiele."Yeast cells illuminate for us what to look for in human cells,"...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...s the antibiotic because it can no longer fit into its target." However, in vitro biochemical assays hav...en combined with careful analysis of the sequence, its neighbors in the genome, and the fact that its gene was also regulated by iron, was that Rv1347c was...

Novel Enzyme Shows Potential As An Anti-HIV Target

...genome pales in comparison to the 3.2 gigabases of its human and nonhuman primate targets. The compact re...polymerases, which carry out transcription—to copy its RNA genome into DNA and infiltrate human chromosomal DNA. Once the virus is integrated (now called a...

The secret lives of whales

...the world. If he hears a whale singing, he can fix its location and position it in space and time and obs...umanity (4.2 billion people) depends on seafood as its primary source of animal protein, and if the fish are seriously polluted, they may soon be unsafe to...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...amp; Stewart remarks, "This is the first patent of its kind to be allowed by the US Patent Office" Dr. Ensley believes that one of the first applications could be in forensic science, where time, the traumatic circumstances of a crime scene or the environment has caused DNA samples to become degraded. "...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...of a Comprehensive Cancer Center in recognition of its excellence in research and contributions to clinical trials, prevention and cancer control. Additionally, Moffitt is a member of the National Comprehensive Cancer Network, a prestigious alliance of the country's leading cancer centers, and is listed ...

Gene therapy converts dead bone graft to new, living tissue

...tissue in the human body, can still perform one of its functions, structural support, even if all its cells are completely dead. A serious problem arises, however, when the bone wears over time. "Every...

Researchers reveal the infectious impact of salmon farms on wild salmon

...fish that compromises a fish's ability to maintain its salt-water balance. When infection rates are high ...ve," says Volpe. "In effect, the farm has exported its lice generating properties ?a cyclical event establishing the potential for re-infections up and dow...

Molecular machine may lead to new drugs to combat human diseases

...mplexes known as a Group I intron, at mid-point in its work cycle. When frozen, crystallized introns reve...ous stages, the scientists can determine and study its three-dimensional structure and learn how it is able to carry out its biochemical work. The Group I...

Jefferson Virologists Coax HIV Out of Hiding

...e body’s immune system. Ifthe new technique proves its mettle, the work could lead to improvedtreatments ...plete viraleradication. TheJefferson team reports its findings January 4, 2005 in the Journal ofClinical Investigation.Dr. Pomerantz, who is director of J...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...n found in cat saliva or dander (small scales from its skin or hair), key immune system cells respond by ...eric molecule GFD, or gamma Feline domesticus, for its human and feline parts, explains principal investigator Andrew Saxon, M.D., of UCLA. The cat allerge...

Color-blind method opens new doors in DNA sequencing

...d/or polymerase chain reaction (PCR) steps, reduce its length to a manageable size of thousands of nucleo...able sequence information. "Genome sequencing, by its very nature, is a process that begs for precision, and the number of mistakes that can be tolerated ...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...usual rate of autismspectrum disorder and explored its link to bromoform, chloroform, andtetrachloroethylene in Brick's water supply--it got her thinking. "Myhypothesis was this: While it had been proven that individually thechemicals don't impact nerve cell development, the combination of allthree might...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...usual rate of autismspectrum disorder and explored its link to bromoform, chloroform, andtetrachloroethylene in Brick's water supply--it got her thinking. "Myhypothesis was this: While it had been proven that individually thechemicals don't impact nerve cell development, the combination of allthree might...

An HIV Protein Plays a Surprising Role in Gene Activation

...s. And they demonstrated that it is Tat—along with its cofactor P-TEFb, which is normally bound to RNA through Tat—that recruits the TAF-deficient TBP. Altogether, these results show a surprising new role for Tat in stimulating assembly of a transcription complex. What's more, the complex lacks the TAFs...

New Clues Add 40,000 Years to Age of Human Species

...s of sediment and link the currently dry region to its moister climates of the past. But, precisely dating the outcrops required volcanic minerals with elements that undergo radioactive decay. Brown and McDougall collected rocks containing volcanic debris, which McDougall dated to approximately 195,000...

A bacterial genome reveals new targets to combat infectious disease

.... Indeed, the Wolbachia bacterium is so crucial to its host nematode that apparently eradicating it with ...ely compromises the nematode's ability to complete its life cycle within its human host. Thus, understanding the details of this relationship may help iden...

Spider Venom Could Yield Eco-Friendly Insecticides

...sy for researchers to aspirate venom directly from its fangs. Since Australian funnel-web spiders can live for more than five years in captivity, a small group of these spiders yields plenty of toxins for King's chemical analysis. Funnel-web spider venom is a complex brew of more than 100 chemical compo...

Gene variations explain drug dose required to control seizures

... drug's variable affects on patient metabolism and its potential neurologic side effects. The team ident...lepsy and is the drug target for phenytoin. Given its relationship to both anti-epileptic drugs tested, the SCN1A variant may be of particular importance ...

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