St. Jude study solves mystery of mammalian ears
...report on this work appears in the advanced online issue of “Proceedings of the National Academy of Science.” “Our discovery helps explain the mechanics of hearing and what might be going wrong in some forms of deafness,” said Jian Zuo, Ph.D., the paper’s senior author and associate member of the St. Jud...FDA sees nanotech challenges in every product category it regulates
...aterials are harmful and which are not. This is an issue that Congressional leaders from both parties have called on the federal government to address urgently,” said Maynard....Common cancer gene sends death order to tiny killer
...ells. Their report will be published in the June 8 issue of Molecular Cell. The research team identified a tiny bit of genetic code, a microRNA called miR-34a that participates in p53's uncanny ability to kill cells likely to become malignant because of damaged genes in their nuclei. MicroRNAs are small ...Researchers discover inherited mutation for leukemia
... The research is to be published in the June 1 issue of the journal Cell. It was led by researchers at the Ohio State University Comprehensive Cancer Center. The mutation was found in a gene called DAPK1, which normally helps trigger the death of cells before they become cancerous. Researchers iden...Cells re-energize to come back from the brink of death
...emotherapy. A report on this work is in the June 1 issue of “Cell.” Apoptosis is triggered by a variety of factors, including gene mutations that can make the cell become cancerous. During apoptosis, the membrane covering the cell’s mitochondria develop holes and leak a molecule called cytochrome c, whi...Brain inflammation may be friend, not foe, for Alzheimer's patients
...n it comes to Alzheimer’s disease. In the June 1 issue of the Journal of Clinical Investigation, a team of scientists from the University of Rochester Medical Center shows that a key inflammatory regulator, a known villain when it comes to parsing out damage after a stroke and other brain injuries, seems...Blood test may help signal tumor's remission, return in throat cancer patients
...ccording to a study published in the June 1, 2007, issue of Clinical Cancer Research . Scientists in the National Institute on Deafness and Other Communication Disorders (NIDCD) and National Cancer Institute (NCI), two of the National Institutes of Health (NIH), in collaboration with researchers of the Un...Pregnant mom's exposure to flu vaccine kick-starts fetal immune system
...ection of antigen-specific T cells. In the June 1 issue of the Journal of Clinical Investigation, a team of researchers led by Rachel Miller from Columbia University used this technique to study cord blood B and T cell immune responses following maternal vaccination against influenza with Fluzone during p...Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes
In the June issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD), researchers report their findings from the first-ever study examining the prognostic value of serum HBV DNA lev...Threats to wild tigers growing
...according to an article published in the June 2007 issue of BioScience. Growing trade in folk medicines made from tiger parts and tiger skins, along with habitat loss and fragmentation, is believed to be the chief reason for the losses. The assessment, by Eric Dinerstein of the World Wildlife Fund and 15 c...Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring
...results of their study are published in the June 1 issue of Cancer Research, a journal of the American Association for Cancer Research. “Here we are looking at male germline mutations, which are mutations in the DNA of sperm. If inherited, these mutations persist as irreversible changes in the genetic ...Discovery in orange cauliflower may lead to more nutritious crops
...Li and colleagues -- and described in the December issue of The Plant Cell -- allows the vegetable to hold more beta-carotene, which causes the orange color and is a precursor to the essential nutrient vitamin A. While cauliflower and many staple crops have the ability to synthesize beta-carotene, they are...Researchers track how spores break out of dormant state
...nces. The research appears in this week’s (June 4) issue of PNAS. “A thorough understanding of spore germination is important for the development of new countermeasures that identify the earliest stages of a wide range of spore mediated diseases, including botulism, gas gangrene and pulmonary anthrax,” ...... discovered. Their findings, published in the June issue of Plos Biology, counter the prevailing belief that HIV and other retroviruses can only leave and enter cells by virus-specific mechanisms. “It appears that cells make HIV and other retroviruses by a naturally occurring export mechanism,” says Step...New study reports hotel guests at risk from carbon monoxide poisoning
...for CO detectors. In a study published in the July issue of the American Journal of Preventive Medicine, researchers from LDS Hospital report on the incidence and impact of CO poisoning of hotel guests. Using data collected at the LDS Hospital Hyperbaric Medicine Department and searches of legal databases...Research team identifies new Alzheimer's gene
...ding APOE4. The study results appear in the June 7 issue of the prestigious peer-reviewed journal, Neuron. Alzheimer’s disease is the most common form of disabling memory and thinking problems in older people. The progressive neurological disorder afflicts an estimated 5 million Americans, a number expect...Largest synthetic gene ever built offers insights into anti-malarial drug resistance
...sily studied. In research published in the May 22 issue of the journal Biochemistry, the researchers say that with the addition of the recreated gene, PfMDR1 and its protein, they have all the biomolecular tools necessary to molecularly understand how the malarial parasite Plasmodium falciparum (P. falcip...Loss of stem cells correlates with premature aging in animal study
...ders in humans. This work appears in the inaugural issue of Cell Stem Cell. “The reason we’re seeing the early signs of aging in these mice is that we’re exhausting their ability to renew tissues,” says Eric J. Brown, PhD, Assistant Professor of Cancer Biology. “We believe these findings may be helpful ...Caribbean frogs started with a single, ancient voyage on a raft from South America
...State, which will be published in the 12 June 2007 issue of the Proceedings of the National Academy of Sciences and posted in the journal's online early edition this week. Similarly, the scientists found that the Central American relatives of these Caribbean amphibians also arose from a single species tha...New bacterium discovered -- related to cause of trench fever
...he U.S. The discovery is reported in the June 7 issue of “The New England Journal of Medicine.” The woman had been traveling in the Peruvian Andes. She suffered from potentially life-threatening anemia, an enlarged spleen and a high fever for several weeks, as do victims of malaria and typhoid. The A...