Cloning techniques produce FDA-approved antibiotic
...st, potentially in much larger quantities. After isolating the genetic information from fosfomycin's native host, Streptomyces fradiae, certain genes were inactivated, and the ability of a non-native host Streptomyces lividians to produce fosfomycin was assessed. With the help of graduate students Ryan Woo...Growth factor stimulates rapid extension of key motor neurons in brain
...l fellow in his laboratory, developed a new way of isolating pure populations of CSMN in culture and found that IGF-1 was a prime candidate for control over CSMN development. Using these purified neurons, they then showed that two ways of applying IGF-1 ?generally adding it to culture dishes or placing IGF-...Researchers from the UGR use a bacterium to obtain biopreservatives from food
...e Granada [ http://www.ugr.es ]), has succeeded in isolating enterocin AS-48, which could have a medium-term use as food biopreservative. This represents a significant advance, given that biopreservation is an innovative method in food-preservation systems based on the use of microorganisms or their metabolic ...Turning green gunk to gold, anti-cancer gold
...figuration. Sherman's team accomplished this by isolating the entire set of biosynthetic genes and key enzymes and developing a new, efficient method to manufacture the broad class of cryptophycin natural products, including important analogs with clinical potential. This included characterization of an enz......n the journal Science on Friday February 2. "By isolating a single gene from a bacterium collected from the mud of Stiffkey marshes, we deduced that the mechanisms involved in DMS production differ markedly from those that had been predicted," said Prof Johnston. "And we discovered that other, wholly unexpe......and at Oxford and Manchester on characterizing and isolating the pacemaker cell. The UIC researchers demonstrated that an enzyme called Pak 1, present in high concentrations in the heart, signals depression in the action of adrenaline and adrenaline-like chemicals on the pacemaker cell, playing an important...