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Tag: "isolated" at biology news

Flesh-eating bacteria escape body's safety net

...from a pathogenic Strep strain that was originally isolated from a patient suffering from necrotizing fasciitis. "Deprived of this single enzyme, the mutant Strep strain was easily killed by human neutrophils", said lead author John Buchanan, Ph.D., research scientist in the UCSD department of pediatrics. "...

Clues to breast cancer hidden inside stem cells

...ment. In 2002, Thorarinn Gudjonsson, successfully isolated cells from the human breast with stem cell properties. Gudjonsson immortalised these cells and grew them in three dimensional matrix that mimics the real, living tissue. Biologists have long relied on 2-dimensional cell cultures as the basic tool of...

Cell barrier shows why bird flu not so easily spread among humans

...ome a pandemic strain," Kawaoka explains. Viruses isolated from humans infected with avian flu can thus be monitored in a way to provide more advance warning of a potential pandemic. "Identification of H5N1 viruses with the ability to recognize human receptors would bring us one step closer to a pandemic st...

Powerful technique for multiplying adult stem cells may aid therapies

...ifferentiate into mature tissue the moment they're isolated from the body. This makes it nearly impossible for...way to multiply adult stem cells once they've been isolated from tissue. Achieving this goal required some intricate laboratory sleuthing. Zhang began by st...

Researchers use dirt to stay one step ahead of antibiotic resistance

... Researchers screened 480 strains of soil bacteria isolated from diverse locations for resistance to 21 clinically relevant antibiotics. At high drug concentrations, the soil-dwelling bacteria displayed a stunning level of resistance. Not only were the bacteria resistant to an average of seven to eight anti...

Researchers release new variety of asparagus

... The male and female plants are then planted in an isolated field. Bees pollinate the females, leading to seed production. These seeds are then sold and planted by farmers who produce the spears consumers eventually will buy. "The first commercial harvest of seeds has only just been completed," Roose said. D...

Potential vaccine developed for deadly leishmaniasis disease

...he United States. Those vaccines use carbohydrates isolated from the actual bacteria responsible for the diseases. The carbohydrates act as antigens, which stimulate the immune system to deploy a protective shield against disease. "Right now there is a major push to utilize synthetic carbohydrates as antigen...

Study outlines genetic differences between potential pandemic influenza strains

...otype Z. There were also small numbers of viruses isolated from avian populations that were genotype V or W or recently identified genotype G. That is where the similarity between the two human strains ended. Previous research published by the World Health Organization has further classified genotype Z int...

New possibilities to fight pests with biological means

... important for scent production. The researchers isolated various genes encoding terpene synthases, the enzymes that produce these scents. One of these genes, TPS10, produced the exact bouquet of nine scent compounds that was released by the damaged corn plant. To demonstrate that TPS10 is indeed the import...

Front-line immune cells mature in four stages, study shows

...of careful, diligent work." The researchers also isolated cells of each stage and showed that under the proper conditions, stage-1 progenitor cells matured into stage-2 NK cells, and that these cells matured into stage-3 cells and stage-4 cells, with the hallmarks and cell-killing capacity of mature NK cell...

Rutgers researchers find fat gene

... baker's yeast; a simple single cell organism. "We isolated the PAP enzyme from yeast that corresponds in form to lipin in mammals and showed that yeast cells lacking the enzyme exhibited a 90 percent reduction in the yeast's version of fat loss," Carman said. The group worked out the sequence of the amino a...

Sea coral's trick helps scientists tag proteins

... tools first made possible by Douglas Prasher, who isolated the gene for green fluorescent protein (GFP) from ...lleagues discovered that the GFP-like protein they isolated from Dendronephthya had this capacity to change color, but it was too big to be useful for many rese...

Minor mutations in avian flu virus increase chances of human infection

...to public health worldwide." Of the H5N1 strains isolated to date, the researchers looked at A/Vietnam/1203/...1 viruses studied so far. The virus was originally isolated from a 10-year-old Vietnamese boy who died from the infection in 2004. The hemagglutinin (HA) struct...

Forsyth scientists gain greater understanding of how embryos differentiate left from right

...he mechanism of action of H+-V-ATPase, researchers isolated its two physiological functions, cytoplasmic pH and membrane voltage gradient (Vmem) regulation. Varying either pH or Vmem, independently of direct manipulation of H+-V-ATPase, caused disruptions of the normal LR pattern, suggesting important roles f...

Salmonella caught red-handed

...e Max Planck Institute for Infection Biology. They isolated Salmonella from infected mice. Proteomics researchers Matthias Selbach and Matthias Mann from the Max Planck Institute of Biochemistry then turned to highly-sensitive mass spectrometry to look at the protein mixture ?and discovered hundreds of differ...

Scientists discover a new disease-causing bacterium in an immune-compromised patient

...life-threatening-- infections result. The team isolated the new bacterium from the patient's swollen lymph nodes and demonstrated its pathogenesis. "Our first concern was to determine whether this organism was truly associated with his clinical syndrome," the team wrote. Despite ineffective neutrophi...

Soil-bound prions that cause CWD remain infectious

...life-threatening-- infections result. The team isolated the new bacterium from the patient's swollen lymph nodes and demonstrated its pathogenesis. "Our first concern was to determine whether this organism was truly associated with his clinical syndrome," the team wrote. Despite ineffective neutrophi...

Novel method reveals how menthol discovery could point towards new or improved pain therapies

...lowed us to analyze 14,000 mutants out of which we isolated five that specifically affected menthol activity. Our experiments yielded significant insights into the functional elements of TRPM8 ion channel protein that would have been difficult to obtain using other mutagenesis methods." Because the methodo...

Scientists discover dozens of new species in 'Lost World' of western New Guinea

An expedition to one of Asia's most isolated jungles ?in the mist-shrouded Foja Mountains of western New Guinea ?discovered a virtual ''Lost World" of new species, giant flowers, and rare wildlife that was unafraid of humans. The December 2005 trip by a team of U.S., Indonesian, and Australian...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

...times through increasingly more potent serum, they isolated the survivors and subjected them to another round ... second generation through serum three times, they isolated viruses that could survive AAV antibodies much better than the original strain of AAV. One strain of...

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