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Tag: "irregular" at biology news

Duke engineers develop new 3-D cardiac imaging probe

...n probes that burn off damaged cells that cause an irregular heart beat. Clinicians must repeatedly and painstakingly reposition the 2-D probe during treatments so, instead, they use fluoroscopy (X-ray movies) to guide the placement of the treatment devices. However, the use of X-ray imaging results in radiati...

Discovery clarifies role of peptide in biological clock

...s internal synchrony is uncoordinated. This causes irregular patterns of sleep and wake, for example." The study was published on-line in Nature Neuroscience on March 6, 2005. Herzog's work is funded by the National Institutes of Health. "In a light-dark schedule, these mice looked normal, but as soon as you...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...romosomes of these cells contain a large number of irregular regions –?where genes have either been deleted or ...ells in the past, enabling researchers to identify irregular sites more precisely. They found a total of 93 regions, each containing about 11 genes, where gene d...

New defibrillator signals doctor of patient's irregular heartbeat or device malfunction

...s, such as a significant increase in the number of irregular heartbeat (arrhythmia) episodes, as well as the preferred alert method, i.e., via email, cell phone, fax or page. "With this surveillance system, physicians for the first time have a way to monitor non-hospitalized heart patients 24-hours-a-da...

NIH renews network focused on how genes influence drug responses

...etermine why drugs used to treat potentially fatal irregular heartbeats (arrhythmias) are beneficial to some people and harmful to others. (Dan M. Roden, M.D., Vanderbilt University) The Amish Pharmacogenomics of Antiplatelet Intervention Study --$7.5 million provided by NIGMS to characterize the geneti...

NYU chemists use computer simulation to enhance understanding of DNA transcription

...esearchers found that the nucleosomal array formed irregular three-dimensional zig-zag structures at high salt concentrations and "beads-on-a-string" structures at low salt, demonstrating that the structure of chromatin strongly depends on its salt environment. To Schlick and her colleagues, these results rev...

Scientists characterize proteome of human cornea

...ers are often the result of incorrect curvature or irregular shape of the cornea and are the most common vision disorders in this country. Other diseases that affect the cornea range from bacterial, fungal, and viral infections (keratitis) and allergies to various dystrophies including keratoconus. "Corneal d...

Genetic testing still smart choice, despite uncertainties

... normal, with no mosaicism, the other half produce irregular cells as they divide. Embryos that become mosaic... Kovalinskaia said. Embryos with only one or two irregular cells still have a chance to develop normally though, she said. These embryos tend to not develop th...

'Computer-chemistry' yields new insight into a puzzle of cell division

..., which the researchers dubbed 'hot spots," on the irregular molecular surfaces. Only when active sites and hot spots fit correctly can this brief docking accomplish its role in the cell division cycle, said Rudolph. That biochemical role is for the enzyme to remove the phosphates from two phosphate-bearing a...

Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm

... factors, genetic and environmental, contribute to irregular heartbeat and other conditions that may lead to sudden cardiac death. Being able to identify predisposed individuals can save their lives by prescribing beta-blockers and other drugs that regulate heart rhythm, and even by implanting automatic defibr...

For one Stanford doctor, the beat goes on during open-heart surgery

...ons such as blood loss, stroke, kidney failure and irregular heart beats were considered, beating-heart surgery had a definite advantage over conventional bypass. "Beating-heart surgery is an advance in cardiac surgery because it provides a better result for patients," said John Puskas, chief of cardiothoraci...

Infections could contribute to adult brain tumours

...quare-kilometre province separately. They found an irregular pattern where many cases occurred at the same time in men and women over 15-years old in the East but not in the West. Around seven per cent more cases of brain tumours were observed to occur in 'clusters' than would be expected by chance. This is...

Component in soy products causes reproductive problems in laboratory mice

...t mice given genistein immediately after birth had irregular menstrual cycles, problems with ovulation, and problems with fertility as they reached adulthood. The new study looks at the direct effects of genistein on the ovaries during early development. "We knew genistein was linked to reproductive problems ...

Mice with glowing hearts shed light on how hearts develop

...use embryos and could improve our understanding of irregular heartbeats, known as arrhythmias, as well as open doors to observing cellular processes to better understand basic physiology and disease. The technique for making living, functional cells fluoresce, or glow, when the concentration of calcium ions r...

Free-radical busting antioxidants might not promote healthy hearts

... along with the bad and the potential to induce an irregular heartbeat. Probucol is still available in Canada and Europe. In their new study, Stocker and his colleagues show that the protective effect of probucol has nothing to do with its ability to scavenge oxygen free radicals, as the free radical-busting ...

Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure

...to gain new insight into the mechanisms that spawn irregular heart rhythms. Studies of the engineered cardiac tissue revealed that while electric shocks such as those delivered by defibrillators usually stopped aberrant waves, in some cases they cause them to accelerate and multiply. The Duke University and J...

With cochlear implants, earlier use leads to better speech

...sentences longer and more complex and their use of irregular words more frequent. The researchers' work was reported in the June issue of Ear and Hearing. Nicholas notes that many of the children who received cochlear implants at the youngest ages have nearly the same spoken language skills as children with ...

Toxic molecule may cause most common type of muscular dystrophy

... cause a slow, progressive wasting of the muscles, irregular heartbeat, cataracts and insulin resistance. Many people don't know they have MMD until their teens or twenties. To prove the theory that toxic RNA is involved in myotonic muscular dystrophy, a research team led by Dr. Mani Mahadevan, a UVa path...

MIT sheds light on how tumor cells form

... Tumor cells that grow aggressively often have an irregular number of chromosomes, the structures in cells tha...ed that mutations in checkpoint proteins cause the irregular number of chromosomes in the aneuploid cells. But they have been perplexed by the infrequent occurre...

UC Davis researchers move biotechnology closer to replacing electronic pacemakers

...ng the more than 2.2 million Americans affected by irregular heartbeats. The UC Davis study, which was co-au...or treating heart arrhythmias ?heartbeats that are irregular in rhythm, rate or sequence. The sinoatrial (SA) node, a patch of cells called the pacemaker, genera...

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