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Tag: "irradiation" at biology news

Enzyme delivered in smaller package protects cells from radiation damage

... with intensive chemotherapy, high dose whole-body irradiation often is given to patients with blood and lymphatic cancers to wipe out their bone marrow cells prior to subsequent transplantation of hematopoietic stem cells, bone marrow stem cells or peripheral blood progenitor stem cells. However, there is incre...

DNA repair proteins monitored at double-strand break

...ch as neurodegeneration, cancer and sensitivity to irradiation leading to double-strand breaks that are not repaired," Kastan said. "And a lack of NBS1 causes Nijmegen breakage syndrome, another disease that leaves its victims at high risk for cancer and higher sensitivity to DNA-damaging radiation. So this work...

Stretching DNA to the limit

...e changes in the mechanical properties of DNA upon irradiation with UV light. Piotr Marszalek and his colleagues have conducted single-molecule force spectroscopy measurements on viral DNA, which show the unraveling of the DNA double helix upon exposure to UV irradiation. The researchers essentially pick up ind...

Non-GMO solution to seafood allergies

...hat treating prawns with a combination of heat and irradiation significantly reduced the level of reactive protei....1002/jsfa.2746). Zhenxing’s team suggests that irradiation damages the proteins, revealing hidden reactive amino acid residues. Subsequent heating then destroy...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

...group had a survival rate of 87 percent. Following irradiation to 9.75 Gy, only 12.5 percent of the mice in the control group survived, while 75 percent of the MnSOD-PL group survived. "Intravenous administration of gene therapy appears to prevent the damaging effects of radiation, suggesting it is a viable...

Eminent inventor of DNA fingerprinting gains new recognition

...onmental factors. He is, for example, studying how irradiation may have caused genetic mutations in families from Chernobyl."Luton-born Sir Alec has formerly studied in Amsterdam as a postdoctoral fellow in the laboratory of Piet Borst, a 1994 Heineken prizewinner. Sir Alec said: "I am honoured indeed to be num...

St. Jude projects 90 percent cure rate for ALL

.... "We are now testing the feasibility of omitting irradiation for all patients and reserving this treatment for ... as the child grows. So our omission of the use of irradiation should further reduce acute and long-term toxic side effects and improve outcome." Coupled with the...

Botox could help target resistant tumors for treatment

...tosis (programmed cellular death) when compared by irradiation without Botox. The combination of Botox and the chemotherapeutic agent cyclophosphamide showed significantly stunted tumor growth after three days, as well. Since Botox is used in clinics without serious toxicity, the study indicates the possibili...

Research casts doubt on circulating stem cells

... because some studies gave grounds for hope. Using irradiation techniques, researchers managed to destroy the bone marrow in mice and replace it with cells which became green-fluorescent thanks to a genetic addition. A short time later they then discovered green-fluorescent nerve cells in the mice's brains. This...

New understanding of DNA repair may pave way to cancer treatments

...o initiate DNA repair processes following ionizing irradiation or other exposures that cause breaks in DNA. A likely way in which ATF2 works is to halt the cell's cycle to allow repair of damaged DNA before such damage becomes permanent." Ronai and his colleagues are now determining how molecules like ATF2 can ...

Light therapy may combat fungal infections, new evidence suggests

...-intensity, full-spectrum or white light bulbs. UV irradiation is also used to repigment skin affected by the aut...for fungal colonization of land, at a time when UV irradiation was particularly intense. ...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...s outcome following initial therapy (chemotherapy, irradiation and surgery). Physicians sometimes treat patients with stem cell transplants as part of therapy for a variety of diseases such as leukemia or sickle cell disease. In these cases physicians eliminate the patients' own stem cells that produce cancerou...

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