Nano-particles effective in killing cancer with one-two punch of chemotherapeutics
... cells." One key feature of molecular mechanism involves putting pores in the cancer cell's membranes and has been simulated with supercomputers by Michael F. Klein and Goundla Srinivas of Penn's Department of Chemistry. While cell membranes and liposomes (vesicles often used for drug-delivery) are created...Protein receptor cools passion of 'kiss and run' nerve cells
... every time it's fired," said Alford. The process involves a receptor protein on a pre-synaptic nerve cell -- the side that fires the packet of neurotransmitter -- that is affected by 5-hydroxytryptamine, or 5-HT, a body chemical often associated with mood. When 5-HT binds to this cell receptor, it activates...World Trade Center identifications pushed forensic DNA technology
...er DNA methods -- mitotyping and SNPs. Mitotyping involves looking at mitochondrial DNA, DNA inherited only from the mother, and comparing it to a standard reference. While mitochondrial DNA is not unique -- entire maternal ancestry lines share the same mtDNA -- it, along with STR, could help in identificat...'Shuttling' protein possibly key to resilience of cancer cells
...ecular fluorescence complementation. The procedure involves breaking a fluorescent protein into two fragments and then fusing each fragment to different AP-1 proteins, including c-Jun and ATF2. When the proteins later bind to form a heterodimer, the fluorescent-protein fragments are reunited, causing them to ...MBL leads effort to update E. coli genome
...orkshops organized by Riley and Serres. Annotation involves identification of genes, and their starting and ending sites, as well as the description of gene products. The process helps scientists to determine gene function. During the MBL workshops, Riley and her colleagues assigned known or predicted gene f......ies to elucidate gene function. The new protocol involves taking strawberry plant tissue from its original site and transferring it to an artificial medium for growth or maintenance. Here unfolded leaves, known as trifoliate leaves, are able to grow. When collected at 6-7 weeks after seed germination, these...Study shows that cells have a natural defense against HIV
...ngs identify a new potential drug target, one that involves a natural host defense," says principal investigator Richard Fishel, professor of molecular virology, immunology and molecular genetics and a researcher with the OSUCCC ?James. "HIV treatments that target cellular components should be far less likely...A new way of looking at molecular motors
...nd over hand along a rope. Making muscles contract involves a large number of motors that work very fast in neatly arranged teams, quickly letting go of the track once they have completed their "power stroke." Most molecular motors have a head, a neck (which powers movement), and a tail. Myosins usually loo...First demonstration of 'teaching' in non-human animals
...s said: "We also believe that true teaching always involves feedback in both directions between the teacher and the pupil. In other words, the teacher provides information or guidance for the pupil at a rate suited to the pupil's abilities, and the pupil signals to the teacher when parts of the 'lesson' have ...Polymer aids in blood clotting, pointing way to new treatment
...emostasis Research. The grant, which began Nov. 1, involves three U. of I. labs with Morrissey in the lead. The PNAS report comes about a year after former Illinois scientist Roberto Docampo, now a professor of cellular biology at Georgia's Center for Tropical and Emerging Global Diseases, documented in the ...Penguins waddle but they don't fall down, UH researchers say
...penguin." Another application for this research involves the construction of sophisticated robots. Kurz said it is very expensive to construct a robot that can successfully adjust to side to side, or medial-lateral, motion. Robots currently in use, such as the Asimo robot that mimics human walking patter...Researchers now able to look deep into heart to view triggers of a heart's beat
...cts make new centrosomes from scratch. The process involves enigmatic cellular structures called accessory nuclei, the function of which has not been explained since they were first discovered in the 1960s. "Centrosomes arise from other centrosomes through duplication, but there is no centrosome in the egg t...Insects that produce males from unfertilized eggs reveal a surprising cellular feat
...cts make new centrosomes from scratch. The process involves enigmatic cellular structures called accessory nuclei, the function of which has not been explained since they were first discovered in the 1960s. "Centrosomes arise from other centrosomes through duplication, but there is no centrosome in the egg t...U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain
...os said. All behavior and cognition in the brain involves networks of nerves continuously interacting--these interactions occur on a millisecond by millisecond basis. Because the interactions in the brain happen so rapidly, it has been difficult to accurately assess them. Current methods of evaluation such...Scientists discover a genetic switch that links animal growth and cancer
... during the formation of tumors in cancer, it also involves the same players," said Rothman. The research team found that PTEN functions with two other proteins –?known as protein kinases –?that are also involved in cancer progression. This discovery means that other proteins that keep the brakes on growth m...Multi-million pound UK Biobank underway
...hat the risk of getting a particular disease often involves a combination of environment, lifestyle, genes ?and chance ?but all studies to date have had limitations, which mean we still don't have a clear picture of how these different elements interact. By being so large and detailed, UK Biobank will be able...Findings advance use of adult stem cells for replacement bone
... engineering, also known as regenerative medicine, involves harvesting stem cells from a patient's body and using them to grow new tissues that can be transplanted back into the patient without risk of rejection. Most tissue engineering approaches involve three components: the harvested adult stem cells, grow...Tool developed to silence genes in specific tissues using RNAi
...ell machinery that destroys the invading RNA. This involves cutting up the double-stranded RNA, separating it ...olves both problems. The technique they developed involves use of two different "modules" that can be swapped in and out of the backbone of a vector. One is a ...How 'hot' emotional brain interferes with 'cool' processing
...ere scanned using fMRI. This widely used technique involves using harmless magnetic fields and radio waves to scan the brain to detect levels of blood flow, which indicates increased or decreased brain activity. In earlier studies, the researchers had found that emotional images activated a "ventral affectiv......ght weeks for broiler chickens. However production involves intensive housing and management to maximise output ?leading to an increase incidence of disease. And, because poultry is a global industry, similar disease problems are found all over the world, as highlighted by the emergence of bird flu. Useful ...