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Tag: "involved" at biology news

Brain-mapping technique aids understanding of sleep, wakefulness

...urnal Neuron, shed light on the complex mechanisms involved in sleep regulation and may help to explain why on...hedding light on the network of neural connections involved in sleep, he said, his and other studies will help unravel the mechanisms involved in sleep homoeost...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...mbers of the Bcl-2 family that block apoptosis are involved in regulating the number of HSCs and progenitor cells," Opferman said. "But our study showed for the first time that a single such Bcl-2 family protein--Mcl-1--is essential for promoting the survival of these cells." Progenitor cells are precursors ...

Revolutionary nanotechnology illuminates brain cells at work

...ses nerve-cell activity in mammalian brains. It is involved in everything from learning and memory to mood and.... The hippocampus is the part of the brain that is involved with emotional reactions, and it helps store learned information in memory. When neurons are activat...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...enzyme, endothelial nitric oxide synthase, is also involved in nitric oxide production in response to infection. This discovery may eventually provide a new target to treat sepsis, which is caused by overproduction of nitric oxide. The research appears as the "Paper of the Week" in the March 18 issue of the ...

Defenseless plants arm themselves with metals

...lly turning on the genes that produce the proteins involved in fighting infection. These infection-fighting proteins also turn off salicylic acid production, a phenomenon known as negative feedback. In this way, plants can turn the pathogen defense pathway on and off as needed. Most plants maintain very low ...

New Estimates For The Causes Of Child Deaths Worldwide

... "Counting the world's children is not all that is involved in making the world's children count. It is important to look at the single most important determinant of childhood death -- which has to be poverty. Childhood mortality is strongly inversely correlated with per-capita health expenditure. In today's ...

Yeast Network Prevents Damage By Oxygen Radicals

...ction of ROS, plus a mutation in one or more genes involved in DNA repair or cell cycle control. Cell survival and accumulation of DNA mutations and gross chromosomal rearrangements in each strain were then analysed to identify genes that cooperate to prevent the deleterious effects of ROS and promote normal ...

Genetic defects give the immune system the green light to attack the pancreas

...his study is that we found the chromosomal regions involved and can now zero in on the precise genes,?said Diane Mathis, Ph.D., the study’s principal investigator along with Christophe Benoist, M.D., Ph.D. They head the Section on Immunology and Immunogenetics at Joslin, and hold joint William T. Young Chairs...

Study reveals new technique for fingerprinting environmental samples

...like the light and temperature. For example, genes involved in breaking down plant material are over represent...absent in the sea water, while in sea water, genes involved in the passage of sodium, a major chemical component of salt water, were particularly abundant. As l...

Used in a new way, RNA interference permanently silences key breast cancer gene

...ne. They chose STAT3 because when activated, it is involved in the formation of multiple types of tumors, incl...sion of a protein called TWIST that is known to be involved in cancer metastasis was drastically reduced in the STAT3 knockdown cells, thus greatly reducing the...

Study: 'homemade' gene expression technology unreliable

...by the NIEHS whose members study how the genome is involved in responses to environmental stressors and toxicants. The three-year, NIEHS-funded study compared a lab-built spotted long oligonucleotide microarray, and a commercially produced long oligonucleotide microarray. The two types were represented among...

Brain-injury rehabilitation depends on acetylcholine circuitry

... that their finding that the cholinergic system is involved in brain recovery is particularly intriguing in light of the fact that deficits in the system have been associated with aging, Alzheimer's disease, and traumatic brain injury. Researchers have long believed that rehabilitation from brain injury caus...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...y microRNA at all. They observed that microRNA was involved in the degradation of genes with AU rich elements, and that the microRNA used only eight bases to target the mRNA. Given that microRNAs have such a short targeting sequence, they may have broad targeting ability, says Han. Significantly, the researc...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...r sites in the genome. The most common breakpoint involved two Ty elements in an inverted, head-to-head orientation, they reported. That finding led the researchers to suggest one possible mechanism for chromosomal breaks and rearrangements. A delay in DNA synthesis leads to an increase in single-stranded D...

Mouse gene shows new mechanism behind cardiac infarction in man

...he gene codes for a protein called OX40L, which is involved in the activation of immunological T cells. These cells, in turn, play an important role in the pathogenesis of atherosclerosis and of a number of chronic inflammatory diseases. The new finding will spur further research into the relationship between...

The evolutionary triumph of flower power

...0 percent of those who got fruit. The second study involved 122 subjects of both sexes in an elevator. When a person entered, he or she either received a flower, a pen or nothing at all. Again, flowers were the emotional winner with recipients smiling, chatting and standing closer together. In the last study...

Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance

...osed in on a region of the t haplotype known to be involved in these phenomena. They used this information to develop transgenic mice that carried the candidate region derived from the wild haplotype. When the transgenic region segregated with the t haplotype, the researchers noted that males carrying two co...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...her laboratory conducts basic research, and is not involved in cancer treatment. Every time a cell divides, t...se activation is just a marker for cancer cells or involved in causing it, telomerase is an attractive target for development of anti-cancer drugs by pharmaceut...

Scientists discover that three overlapping signals in embryo help get the backbone right

... assays that are good enough to find the molecules involved in the normal process," Harland said. Postdoctoral fellow Bill Smith and Harland found the first of these BMP antagonists, noggin, in 1992, confirming its activity by repeating Spemann and Mangold's experiment but injecting noggin instead of implant...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...th's issue of the Annals of Neurology The animals involved in the study are born with a genetic disorder directly analogous to alpha-mannosidosis or AMD, an inherited disease in humans that causes severe mental retardation and skeletal abnormalities. Cats with AMD do not live more than six months. Children b...

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