Scripps research scientists identify infertility molecule
...and nobody has ever considered LPA signaling to be involved in implantation. If the same pathway turns out to be relevant in human embryo implantation, then there might be a way to stimulate LPA signaling with a drug that would increase the odds of implantation for women undergoing assisted reproduction. The...Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief
...egal issues surrounding the drug. Others from UGA involved in the study include faculty members Philip Holmes...ounds. "We showed that cannabinoid receptors were involved in this remarkable phenomenon," said Hohmann, "because blocking the receptors where marijuana acts v...Blink, and the brain misses it
... world. "Transiently suppressing these brain areas involved in visual awareness during blinks may be a neural mechanism for preventing the brain from becoming aware of the eyelid sweeping down over the pupil during a blink and the world going dark," explains Professor Frith. In summing up the study's implicat...Researcher gets NSF grant to create mutant maize lines
...c researchers interested in how specific genes are involved in basic developmental or physiological processes, as well as to biotechnology industry scientists seeking to create maize plants with enhanced properties for agriculture or industry, Brutnell says. "This is going to be the only resource of its kind...Biologists determine genetic blueprint of social amoeba
...s seven-year-long genetic sequencing effort, which involved 97 scientists from 22 institutions in five countri... of Dictyostelium's genome. Another UCSD biologist involved in the genome effort, Christophe Anjard, an assistant project scientist in Loomis' laboratory, analy...Newly discovered genetic disease sheds light on body's water balance
...lled G protein-coupled receptors (GPCR), which are involved in signal transduction and are responsible for many physiological processes. Normally, when vasopressin binds to the V2R, it stimulates a chain of events inside the cell. Vesicles containing the water channel Aquaporin 2 (AQP-2) are shuttled from th...Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
...esearchers found that 38 percent of all operations involved a bloodborne pathogen, and almost half (47 percent) of all men tested positive for at least one infection. HIV accounted for 26 percent of infections, hepatitis B for 4 percent, hepatitis C for 35 percent, and co-infection with HIV and hepatitis C ac...Breakthrough: Scientists create world's tiniest organic particles
...ible with organic materials. That was because they involved baking, etching or processing robust metals and such with solvents that would have destroyed far more fragile organic matter such as genes or drugs. The new method avoids harsh treatment but also allows formation of uniform particles in any shape de...Researchers identify new genes that regulate aging
...gnaling, metabolism, and dietary regulation. Genes involved in insulin signaling are particularly interesting because corresponding human genes could potentially play a role in diabetes and cancer, according to senior author Cynthia Kenyon, of the University of California, San Francisco, and her coauthors. C...A protein in the eye may prevent immune response and protect eyes from disease
...unknown, the team believes that the protein may be involved in cell-cell communications. The presence of F4/80 cells in other immune privileged sites, such as the brain and placenta, and its exclusion from T cell zones in the spleen suggests that F4/80 expression and immune activation may be mutually exclusi...Scientists find microRNAs regulate plant development
... repress the expression of a number of other genes involved in auxin responses. Dr. Bonnie Bartel at Rice University in Houston, TX together with Drs. David Bartel and Allison Mallory at the Massachusetts Institute of Technology and the Whitehead Institute for Biomedical Research in Cambridge, MA report expe...Novel plague virulence factor identified
...Aballay believed that other virulence factors were involved in infecting the worm. "We thought that a Y. pestis strain (known as KIM5) that lacks the genes (hmsHFRS operon) required for biofilm formation could still enter the worm's digestive system and eventually kill it by using a method different from foo...Unraveling a stomach cancer puzzle
...to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and we have a compelling case for investigating the development of therapies that target Stat3." ...New Look at DNA Hints at Origin of UV Damage
...Aballay believed that other virulence factors were involved in infecting the worm. "We thought that a Y. pestis strain (known as KIM5) that lacks the genes (hmsHFRS operon) required for biofilm formation could still enter the worm's digestive system and eventually kill it by using a method different from foo...Can our genes tell the story of our divergence?
...oth species. Nielsen et al. identified many genes involved in sensory perception, as well as spermatogenesis, but found the strongest evidence for positive selection in genes related to immune defense. Immunity genes, the authors explain, were likely targeted throughout mammalian evolution, while the percept...Scientists discover that three molecules may be developed into new Alzheimer's drugs
...ll globs. All proteins that happen to be an enzyme involved in phosphorylation have one thing in common. They have a pocket that is almost always in the same place and this is where the phosphate attaches to the enzyme, in this case CDK5. To get a molecule that specifically prevents the enzyme from binding at...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...ll globs. All proteins that happen to be an enzyme involved in phosphorylation have one thing in common. They have a pocket that is almost always in the same place and this is where the phosphate attaches to the enzyme, in this case CDK5. To get a molecule that specifically prevents the enzyme from binding at...Attacks of King George III's madness linked to key metabolism molecule
...hat acts as an on-off switch for a number of genes involved in manufacture of glucose in the liver and in the ...he Dana-Farber researchers wondered if it might be involved in porphyria, since PGC-1 alpha is a regulator of heme manufacture in the liver. One of its actions ...New protein vital for immune response is found in surprise location
...his is the first mitochondrial protein known to be involved in immune defense against any microbial infection,...n trying to identify and characterize the proteins involved in an effort to better understand the nature of viral infection and how to combat it. Dr. Chen said...Compound might defeat African sleeping sickness, clinical trial beginning this month
...da Gates Foundation as board members. Laboratories involved in the discovery of the new drug candidates are ru...ick and J. Ed Hall of UNC. Scientists also closely involved are Drs. Simon Croft at the London School of Hygiene and Tropical Medicine and Reto Brun and Christi...