Parasitic worms used to fight bowel disease
...Mansfield is part of a national team of scientists investigating the role that parasites can play in treating inflammatory bowel disease, or IBD, in humans. Her research is part of a more than $10 million National Institutes of Health grant supporting the Food and Waterborne Diseases Integrated Research Network o...New potential drug target in tuberculosis
...s Matthias Wilmanns, Head of EMBL Hamburg. "We are investigating the functions of tuberculosis proteins and determining their atomic structures, in hopes of finding weak points and new inhibitors." A protein called LipB is essential for the organism because it activates cellular machines that drive the bacterium'...Trial success for diabetic nerve therapy
...europathy are not fully understood but researchers investigating the effect of glucose on nerves believe it is likely to be a combination of factors. ...Inflammation and drugs to control this activity studied in a variety of tumors sites
...ry processes and tumor formation, while others are investigating anti-inflammatory drugs as a means to prevent and treat cancer, as seen by studies presented today at the 97th Annual Meeting of the American Association for Cancer Research. Antihistamine and Anti-inflammatory Drug Use Associated Differently for H...Radiotherapy advance points way to noninvasive brain cancer treatment
...n cure animals from their cancers, then it's worth investigating the molecular biology of this drug and seeing what the uptake mechanism is," she says. "But first, you want to know that it works and that it really has potential for saving lives." Because of the deadly nature of GBM, De Stasio says an alternative ...Salmonella bacteria use RNA to assess and adjust magnesium levels
...uncovered the magnesium riboswitch while they were investigating the MgtA gene, which is controlled by the major regulator of Salmonella virulence, the phoP/phoQ system. The MgtA gene codes for a protein that can transport magnesium across the bacterium's cell membrane. Groisman's group showed 10 years ago that th...Newly discovered killer cell fights cancer
...t do not actually kill the invaders. It was while investigating a particular type of dendritic cell that Housseau noticed the outer membranes of these cells were studded with what were supposed to be hallmarks of NK cells, akin to finding feathers on a dog. "We thought we were looking at dendritic cells, but we ...All placebos not created alike
... placebo effect as a generalized phenomenon to one investigating how it varies in specific clinical environments. Kaptchuk and his colleagues have initiated other National Institute of Health funded studies that will explore the placebo phenomenon in clinical trials for different illnesses and in laboratory experi...... objects into space in a rocket like that. 'We are investigating which genes plants switch on and off under particular gravity conditions,' he explains. 'However, with the methods we use we can also, for example, find out which genes the sunflowers activate when they produce DCQA in reaction to a fungus infection....Worm hormone discovery may aid fight against parasitic disease
... intestine and begin to mature. Dr. Mangelsdorf is investigating whether the homologue of DAF-12 in parasitic nematodes may regulate their maturing activity as well. If so, he said, the same pathway could be exploited to eradicate the pests, either by keeping them perpetually in an immature state, or by coaxing th...The giant protein titin helps build muscles
... complex structures, and for many years we've been investigating the steps by which they are formed," says Matthias Wilmanns, Head of the EMBL Hamburg Outstation. "That probably starts when proteins link up to each other in very big assemblies. The meeting point is the Z-disk, but unraveling the connections has be...Penguins waddle but they don't fall down, UH researchers say
...ng penguins are the subjects of a research project investigating balance and locomotion. "Compared to other terrestrial animals, penguins have an excessive amount of side-to-side, waddling motion," Max Kurz, UH Health and Human Performance professor said. "If humans waddle too much they fall, but penguins so...A new focus for the mechanism of nerve growth
...naling may be intimately related. The team is now investigating the implications of these findings for control of nerve growth, with particular interest in repair of spinal cord nerves after injury. ...Curry and cauliflower could halt prostate cancer
...e properties. Consequently, scientists have been investigating intervention options based on compounds found in edible and medicinal plants. They have had some success, and a majority of patients with prostate cancer are now combining the conventional therapies with these compounds as alternative, supplementary ...HortResearch science reveals the natural potential of apples
...ics as fruit colour and taste. By identifying and investigating only these active genes, researchers can avoid the high costs and long timeframes associated with full genome mapping projects. A number of research teams from around the world have been working on identifying apple ESTs, and this will be the 2nd ti...Mayo Clinic collaboration discovers protein amplifies DNA injury signals
...o cue the repair process, the Mayo researchers are investigating another system that appears to play a similar role in the cell. "If we can understand all the pathways involved in signaling the DNA repair process, we may be able to develop a comprehensive approach to managing the signals to treat disease," says Dr...CU, USDA team to curb two invasive, poisonous vines
...ree days. DiTommaso and his graduate students are investigating whether the plants release root chemicals that alter soil conditions. Preliminary findings suggest that communities of mycorrhizae -- soil fungi that help provide more nutrients to plant roots -- differ in species and abundance in areas surrounding s...H5N1 avian flu virus vaccine induces immune responses in healthy adults
...uently at the highest dose of this vaccine. We are investigating other options that may allow us to reduce the dosage--for example, adding an immune booster, or adjuvant, to the vaccine--so we can achieve a more practical immunization strategy." In addition, the U.S. Department of Health and Human Services is purs...Largest study of human 'interactome' reveals a novel way
...nates a blind alley that could mislead researchers investigating the roles of specific proteins in the cell." Pandey is the chief scientific advisor to the IOB and senior author of the Nature Genetics article. The team's conceptual advance was made by comparing human data with 6,014 genes in yeast and 2,284 gene...Research investigating attention in infancy has revealed that, at just fo...onomic and Social Research Council funded research investigating different styles of visual attention in babies from the age of two to eight months. Paying attention...