Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
...ntegration. He hopes that he will soon be able to investigate how the concept of transplanting photoreceptor precursors can be adapted to the human retina. "Perhaps within the next five years we will begin to see the first steps toward retinal cell transplants for people with blinding eye disease," says Swaroo...Two nerve cells in direct contact
...s, and it was this non-linearity that we wanted to investigate further," said Alexander Borst. The next step was to analyse the circuit diagram of the tangential cells of the lobula plate in detail. This was based on a multitude of experiments in which the connections between the cells within one lobular plate...Evolution of influenza A virus
...tute for Genomic Research used genomic analysis to investigate the evolutionary properties of the H3N2 subtype of human influenza A virus. The authors, in the first population-based study of its kind, collected a sample group of 413 complete influenza genomes from across New York State. Comparative analysis of ...Early-stage immune system control of HIV may depend on inherited factors
...study with samples from 500 individuals to further investigate the impact of HLA Class I on the control of HIV replication. ...Trying to control pain can be a double-edged sword, say scientists
..." Dr Wiech and her team set up an experiment to investigate how people cope with pain. In the first stage, volunteers were given an electric stimulus to the backs of their hands and told that they could stop the pain at any point. In the second stage, they were told that the decision to stop the pain was out ...White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells
... in humans, the researchers have also continued to investigate how the original mutation works, a mutation that protects the cancer-resistant mice from a wide variety of injected cancer cells. Cui and Willingham said the killing of the cancer cells in the cancer-resistant mouse requires three distinct steps:...A sweet step toward new cancer therapies
... U-M Health System cancer surgeon Diane Simeone to investigate sugars attached to proteins in the membranes of pancreatic cancer cells. "The work is in very early stages, but we hope that by measuring unique sugars it may be possible to develop diagnostic tools or therapeutic agents to specifically target the...Widely used hepatitis B drug spurs HIV drug resistance
...mpromised by entecavir, she says. Thio began to investigate entecavir's effects on HIV in fall 2006 after noticing reports of anti-HIV activity in two co-infected patients, one at the Johns Hopkins Moore Clinic, which specializes in HIV/AIDS care, and another at a San Diego medical center. The patients (and ...Novel laboratory technique nudges genes into activity
...roviding researchers with a novel research tool to investigate the role that genes play in human health. In a paper appearing online at Nature Chemical Biology and in an upcoming edition of the journal, lead author Dr. Bethany Janowski, assistant professor of pharmacology at UT Southwestern, and her collea...New insights into autoimmunity and depression
...he central nervous system, anti-ribosomal P. To investigate how an autoantibody could stimulate behavioral changes by interaction with the brain, researchers at Tel Aviv University set out to induce depressive hallmarks in mice. Their findings, presented in the March 2007 issue of Arthritis & Rheumatism (...Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
... then allowed to explore. Wild-type mice tended to investigate first one, then the other arm of the maze, while untreated Down syndrome mice were less methodical. However, the Down syndrome mice performed more like their wild-type counterparts on both tests after 17 days of PTZ treatment. The researchers disc...Manual dishwashing study digs up dirt on dish cleanliness
...drop in amounts of bacteria on those dishes. To investigate effective lower-temperature dishwashing tactics, the researchers coated dishes individually with cheese, eggs, jelly, lipstick, and milk, and then added Escherichia coli and Listeria innocua bacteria. Contaminants like E. coli and L. innocua can surv...Nanoparticles can track cells deep within living organisms
...ong they live," Partlow says. "Then we'll go on to investigate how they work in therapeutic applications." ...Common mechanisms for viral DNA replication
...tanding life. DNA replication remains difficult to investigate in eukaryotes,where it occurs within the confines of the double-membrane nucleus. However, the process is far easier to study in the much simpler virus. In simian virus 40 (SV40), the large T-antigen protein (T-ag) is responsible for recognizing DNA ...DNA layer reduces risk of reserve parts being rejected
...owing this successful result, Van den Beucken will investigate whether DNA layers can be used for the application of DNA membranes to prevent post-operative adhesions, and in biosensors such as an implanted glucose sensor for diabetic patients. ...Research to spotlight carbon monoxide benefits
...University of York have won a grant of £110,000 to investigate potential uses of carbon monoxide in treating disease. Dr Jason Lynam and Dr Ian Fairlamb, of the University's Department of Chemistry, have been awarded the funding by the Leverhulme Trust for a three-year study into the use of metal compounds for...Lizards 'shout' against a noisy background
... communication. So Ord is using them as a model to investigate the evolution of such signals. ...Scientists unravel clue in cortisol production
...optimal levels of cortisol." Next the team will investigate how small molecules ?ligands ?regulate cortisol production by binding to SF-1 and controlling the receptor's ability to bind to DNA. ...Lower carbon dioxide emissions from coal-fueled power plants possible with technology development
...int Industry Project for Geologic CO2 Storage will investigate how carbon dioxide captured using Rochelle’s process will behave if stored underground in a high-pressure, liquid form. Sandstone formations common in Texas and some other states are already being considered nationally for this type of storage. Co......the Libyan authorities and are encouraging them to investigate these 'hotspots' further. One of the major threats to marine turtles globally is fisheries bycatch. Hundreds of thousands of marine turtles die each year as a result of fisheries interactions. Identifying and protecting key habitats is critical fo...