Study: Harmless virus kills some cancers
...classified as a gene therapy. Future studies will investigate the precise mechanisms through which AAV2 causes cancer cell death, and how the virus might be enhanced to more aggressively target and kill cancers. A provisional patent application for this work was recently submitted. ...Could better mangrove habitats have spared lives in the 2004 tsunami?
...ter, academics and politicians alike are trying to investigate how the number of casualties could have been reduced and, more important, how such severe damage can be avoided if a tsunami ever strikes again. In an essay published this week in the June 21 issue of Current Biology, a group of researchers recount t...Stem Cells to Solve the Blood Shortage Problem?
...ter, academics and politicians alike are trying to investigate how the number of casualties could have been reduced and, more important, how such severe damage can be avoided if a tsunami ever strikes again. In an essay published this week in the June 21 issue of Current Biology, a group of researchers recount t...Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory
...for doing this research is that it may allow us to investigate the very earliest processes of how a human gamete ...m cells as they differentiate to germ cells we can investigate the action of these chemicals in the laboratory. "Ultimately it might be possible to produce sperm ...Gene expands malaria's invasion options
...can switch - so it has two methods of entry." To investigate how the parasite manages to switch to an alternative mode of blood cell invasion, Cowman and colleagues produced lines of the W2mef parasite that used sialic acid for invasion, and lines that could invade without it. Then they compared the difference...Spiders help scientists discover how muscles relax
...he structure of the relaxed state will allow us to investigate how these filaments are activated when they are switched on." The scientists were surprised to find that the atomic structure of isolated myosin molecules from vertebrate smooth muscle--the type of muscle found in the digestive tract, bladder, arte...Researchers track down cause of a disfiguring bone disorder
...s diseases or defects) if altered or deleted." To investigate the misregulation of the SOST gene, Loots and her colleagues genetically engineered a copy of the DNA segment containing the gene and used it to generate mice with and without the 52,000-base-pair region missing in Van Buchem patients. The deleted re...Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress
...age to neuronal homeostasis. "Our next step is to investigate cannabinoids' effects in various stress conditions," Soya said. "Endocannabinoids may have possible involvement in stress-induced responses such as the changes of autonomic, endocrine and immune function." Furthermore, Soya added, "cannabinoids are ...Scientists focus on 'dwarf eye'
... that signaling process." Sundin plans to further investigate MFRP and ultimately develop drugs to regulate the gene's function. He hopes the information gained from his study will open doors to correcting other types of severe refractive error, not only farsightedness, but also nearsightedness. ...Fruit fly studies open new window on cancer research
...tracted funding from Cancer Research UK to further investigate the processes involved and allow Dr Goberdhan to establish her own group. Professor Julia Goodfellow, BBSRC Chief Executive, remarked, "Although research into fruit flies may not seem an immediate priority, only fundamental research such as this can...NIH renews network focused on how genes influence drug responses
...11.6 million provided by NIGMS, NIEHS, and ORWH to investigate how genetic differences explain variable responses to tamoxifen and hormone treatments frequently prescribed to treat breast cancer. (David A. Flockhart, M.D., Ph.D., Indiana University School of Medicine) The Pharmacogenetics of Membrane ...... the food supply. Further research is going on to investigate the running and swimming mechanisms in more detail. ...Discovering an ecosystem beneath a collapsed Antarctic ice shelf
.... He added that there may be a sense of urgency to investigate the unusual seafloor ecology below the Larsen shelf because of the likelihood of increased sediment deposition. In addition, he suggests that the newfound system may provide incentive to launch studies to other remote undersea environments in the po...Hybrid grass may prove to be valuable fuel source
...e as much biomass as switchgrass, Heaton said. To investigate how Miscanthus is so productive, Dohleman and others take measurements of photosynthesis throughout the day. He measures the intensity of the sun and then places a leaf in a chamber, allowing him to measure the rate of photosynthesis depending upon a...Secrets of the deep may hold key to life on other planets
...gn and build seafloor fossilisation experiments to investigate this fundamental process. "We've already found a number of fossils, but don't know how they came to be there," said Dr Little. "Until we know more it's very difficult to interpret the fossil record we already have." Pieces of hydrothermal animals ha...Monkeying around to improve organ transplantation
...hi Bashuda and colleagues from Juntendo University investigate whether this approach can induce indefinite organ allograft survival in vivo, in six rhesus monkeys. The authors stimulate recipient T cells from the monkeys with donor cells under conditions associated with the development of T cell anergy. Reinfus...Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development
...udy was devised by Young and Melikyan last year to investigate viral infection in a manner as close to 'real life' as possible. The researchers filmed the microscopic viruses, which are only 100 nanometers across, by labeling them with fluorescent dyes and recording at one frame every 7 seconds. (For comparison ......elona, on Wednesday 13th July [session A7.15]. To investigate responses in Drosophila melanogaster, she performed experiments dropping black discs from different angles, on a collision course with the flies. Capturing the responses on video, she showed that flies escaped by means of jumping in a forward fashion...Scientists uncover new clues about brain function in human behavior
... was the cause of the amygdala abnormalities." To investigate this, the scientists looked at the whole brain to identify other regions where reactivity was different between Williams's participants and healthy volunteers. They identified three areas of the prefrontal cortex, located in the front part of the bra......rsity, UK, have designed world-first technology to investigate sustainable energy sources from the ocean bed by isolating ancient high-pressure bacteria from deep sediments. Scientists and engineers at Cardiff University are investigating bacteria from deep sediments which despite high pressures (greater than 1...