Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia
...r widely used antileukemic agents. They went on to investigate the relationship of these genes to treatment outcome in ALL patients and found that expression of the genes was associated with treatment outcome and could be used to identify a subset of patients with a markedly inferior response to treatment. In ad...Basis for DNA ejection from single phage particles
...esearchers used fluorescently labeled phage DNA to investigate in real time (and with a resolution time of 750 milliseconds) the dynamics of DNA ejection from single phages. The ejected DNA was measured at different stages of the ejection process after being stretched by applied hydrodynamic flow. The study demo...'Smart drug' targets deadly brain cancer
...xt Step Mayo Clinic researchers are continuing to investigate the implications of their findings. NCCTG studies now under way will test the combination of CCI-779 with radiation therapy in patients who have newly diagnosed glioblastoma multiforme. They will also test CCI-779 in combination with other targeted t...WHO suspends Marburg work, appeals for new funds
...day of several fatalities but teams were unable to investigate the cause of death or collect the bodies for safe burial. Discussions have been held with provincial authorities to find urgent solutions. The dramatic symptoms of Marburg haemorrhagic fever and its frequent fatality are resulting in a high level of...Next Generation Body Scanner Launched By The University Of Manchester
...esearch is currently underway at the University to investigate vascular abnormalities to the kidneys in patients with renal disease. The scanner, which has been manufactured by Philips Medical Systems and features a 5.5 tonne magnet, will be launched by Professor Colin Blakemore, Chief Executive of the Medical ...Chemists synthesize molecule that helps body battle cancers, malaria
..., we are in a position to examine how it works and investigate ways to improve its performance," said David Y. Gin, a professor of chemistry at Illinois. Gin and his collaborators describe their work in a paper that has been accepted for publication in the Journal of the American Chemical Society, and posted on ...Virologists make major step towards understanding the process of HIV infection
...Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this basic research are expected to lead to new approaches in the prevention, diagnosis and treatment of cancer. The Center is financed to 90 percent by the Fede...New Species of Coral Discovered Off Southern California
...Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this basic research are expected to lead to new approaches in the prevention, diagnosis and treatment of cancer. The Center is financed to 90 percent by the Fede...Whole genome promoter mapping - Human Genome Project v2.0?
...study how the genetic switches work in a cell, and investigate their connection to human diseases," said Dr. Ren, who is also a member of the Rebecca and John Moores UCSD Cancer Center. He and his colleagues have made the data freely available on online public databases. Dr. Robert Strausberg, Vice-President of...Census of Marine Life explorers surprised by diversity, density of Arctic creatures
... goes on in the Southern Ocean, biologists want to investigate its role as a cradle of genetic diversity. The Antarctic Census will take extensive samples from the deep abyssal plain on the sea floor, 4,500 to 5,500 meters below surface, research that holds huge promise for biologists. Says Dr. Ron O'Dor, Chie...Random gene expression may drive HIV into hiding
... of stochasticity in gene expression to those that investigate the consequences of such molecular noise on cellular function. The authors [present] a scenario in which HIV-1 can hedge its bets by having an inherent ability to proceed either to latency or viral production. This intriguing notion still needs to be...Enzyme's newly discovered role may make it target for arthritis treatment
...ns besides arthritis. She plans further studies to investigate this possibility. Her lab is also working to determine what molecules cathepsin G is sticking to and interacting with on the surfaces of neutrophils and other cells. ### Raptis SZ, Shapiro SD, Simmons PM, Cheng AM, Pham CTN. Serine protease Catheps...Study finds adult stem cells can replicate
...ns besides arthritis. She plans further studies to investigate this possibility. Her lab is also working to determine what molecules cathepsin G is sticking to and interacting with on the surfaces of neutrophils and other cells. ### Raptis SZ, Shapiro SD, Simmons PM, Cheng AM, Pham CTN. Serine protease Catheps...Proteomics brings researchers closer to understanding microbes that produce acid mine drainage
...or of DOE's Office of Science. "Now scientists can investigate not only the community genome, but also the resulting community proteome for enzymes and pathways that can help clean up some of the worst environmental sites in the nation. This underscores the value of basic research carried out by the DOE Genomics...ORNL, UC Berkeley unravel real-world clues to Earth's mysteries
...taminated sites," Orbach said. "Now scientists can investigate not only the 'community genome,' but also the resulting 'community proteome' for enzymes and pathways that can help clean up some of the worst environmental sites in the nation. This underscores the value of basic research carried out by the DOE Geno......id arthritis," added Nakamura. Future studies will investigate the role of Wnt and its signaling partners in arthritic joint destruction. Further delineation of the Wnt signaling pathway in arthritic progression may provide future therapies for the growing number of arthritis suffers. According to The National ...New Vaccine To Be Used For First Time In Polio Outbreak Response
...ogists and paediatricians remain on the ground, to investigate and control the outbreak and to intensify the planning for appropriate supplementary immunization activities. Four cases of polio were confirmed on 20 April in just one governorate in the south-western part of the country, on the Red Sea coast. The ...Male Combat Veterans Rank High In Heart Disease Risk
...said. In the future, the ongoing LCSES study will investigate the relationship between cardiovascular risk factors and morbidity and mortality. ...New tool reveals secrets of migrating cells
... signal. Robey hopes to use two-photon imaging to investigate the signals responsible for changing these meanderers into purposeful beeliners that immediately leave the cortex for the interior medulla of the thymus. "We're now at the point with this technology that we can begin to look at the movement of signa......her compounds coming from plastics etc, we need to investigate their possible effects on the fertility of human sperm as quickly as possible." ...