DNA analysis reveals rapid population shift among Pleistocene cave bears
...rnal Current Biology, published by Cell Press. To investigate the stability of ancient cave bear populations over time, the researchers obtained DNA samples from 29 cave bear teeth from three geographically close caves in the Ach Valley, near the Danube River in modern-day southern Germany. Twenty of the teeth ...New research may overturn conventional wisdom on drug-resistant tuberculosis
...ecular genetics and drug susceptibility testing to investigate patients with TB who were treated in Shanghai hospitals during 1999-2004. They focused on 38 patients from whom samples were available before and during treatment. The researchers found that the strains of TB in the samples taken before treatment wer...Active ingredient in common Chinese herb shown to reduce hypertension
...ly available, a team of researchers has used it to investigate if this active ingredient can reduce blood pressure. In a soon-to-be-released study, using an animal model, the scientists have found that tanshinone IIA does reduce blood pressure. Summary of Methodology To assess the effect of tanshinone...The origin of the brain lies in a worm
...Arendt and his group study at EMBL. To do so, they investigate the nervous system of a marine annelid worm called Platynereis dumerilii. "Platynereis can be considered a living fossil," says Arendt, "it still lives in the same environment as the last common ancestors used to and has preserved many ancestral fe...Stopping plants from getting sick
...er Island, applying his research on plants to help investigate how this yeast causes pneumonia, meningitis and other illnesses in humans and animals. Still, he says he expects to be kept busy studying fungi for a long time ?keeping the sooty black smut and the smell of rotting fish from Canada's wheat fields. ...Swell gel could bring relief to back pain sufferers
...ower back pain." He added that future work will investigate biodegradable microgels that release additives to stimulate regeneration of intervertebral disc tissue. ...Molecular signature may identify cisplatin-sensitive breast tumors
... study was designed to answer that question and to investigate the mechanism underlying cisplatin sensitivity. ...Harvard Medical School. The clinical trial to investigate the role of p63/p73 expression in determining cisplatin sensitivity will be led by MGH researchers t...Some caterpillers just don't want to grow up
...om the universities of Würzburg and Montpellier to investigate this problem. Together they have compiled various potential adaptive explanations for the evolution of such strategies into a general and quantitative model. "The problem was not the lack of, but multitude of alternative mechanisms principally capabl...New research shows that flu is a trigger of heart attacks
... and in St Petersburg in the Russian Federation to investigate deaths between 1993 and 2000 in St Petersburg that had been shown by autopsy reports to be due to coronary heart disease. "This was a population where only a small minority were receiving flu vaccines or statin drugs, so this enabled us to see wha...Global 'sunscreen' has likely thinned, report NASA scientists
...ter simulations of Earth's 20th-century climate to investigate the dimming trend. The combined results from nine state-of-the-art climate models, including three from GISS, showed that due to increasing greenhouse gases and aerosols, the planet warmed at the same time that direct solar radiation reaching the sur...Scientists find new genetic clue to cause of Alzheimer's disease
...orms of this very complex disease. We are eager to investigate the role of this gene further." Scientists think that in Alzheimer's disease, amyloid precursor protein, or APP, is processed into amyloid beta protein fragments that make up plaques in the brain. The researchers began their search for genetic infl...Genes and biomarkers that allow doctors to choose the right therapy for the right patient
... Dr. Laurent-Puig and colleagues are continuing to investigate the molecular biomarkers associated with cetuximab, including in tumors without the KRAS mutation that do not respond to the drug. Recombinant peptides as biomarkers for cancer response to tyrosine kinase inhibitors combined with radiation: Abs...White blood cells in lung produce histamine seen in allergies
...ext steps for Caughey and his research team are to investigate "how general this result might be. Does only one type of bacteria cause the effect, or do others, also? Is it limited to rodents, or does it carry forward to humans? And if it does, is the amount of histamine produced by neutrophils enough to make a ...What recognizes what in plant disease resistance?
...thors used N, and the TMV Avirulence gene, p50, to investigate the mechanism of gene-for-gene resistance. Contrary to current models, which propose that recognition of resistance genes occurs solely through their leucine-rich repeat domain, the authors show that association is mediated by a completely different ...UCSF brain tumor vaccine trial shows promising results
...ould urge patients to seek out second opinions and investigate clinical trials. I can tell you I am so glad I did.? “Our goal is to change the management of recurrent glioma from a life threatening disease, in which survival rates are typically 25 to 26 weeks, into a chronic disease with extended survival and ...Scripps research study reveals structural dynamics of single prion molecules
...d a combination of advanced biophysical methods to investigate these processes. "By focusing on single unfolded prions, we were able to define the dynamics of two distinct regions or domains that determine conversion dynamics," said Ashok A. Deniz, a Scripps Research scientist who led the study. "Our research...Cartilage discovery offers arthritis hope
...rm and develop in healthy cartilage, they can then investigate what happens when things go wrong in diseases like osteoarthritis. ...Researcher to study astronaut bone loss for space biology agency
...ion of new bone cells, leading to bone loss. To investigate the hypothesis, Long will take a two-pronged research approach. In the first part, he will study a model of skeletal loading and unloading in human bone cell culture. In the second part, skeletally unloaded rats will be treated with IGF-1 and reloade...UW launches study testing adult stem cells for heart damage repair
...stem cell therapy study in the U.S. Its goal is to investigate the efficacy, tolerability, and safety of blood-derived selected stem cells to improve symptoms and clinical outcomes in patients with chronic myocardial ischemia (CMI), a severe form of coronary artery disease. Myocardial ischemia, which affects h......ich creates myelin, researchers may now be able to investigate new therapies for disorders affecting myelin. "Our research has uncovered a whole new mechanism for regulating myelin genes," said Dr. Svaren. "Our hope is to exploit this knowledge so that we can adjust the levels of myelin genes such as PMP22 a...