Tag: "investigate" at biology news

Man and mouse share genome structures

...earlier, working with the smaller yeast genome. To investigate the much larger human genome, they collaborated with Affymetrix. They isolated the DNA regions with certain major methyl and acetyl tags, and used new microarray technology to identify the underlying genetic sequences associated with the tagged chrom...

Research on Worms Yields Clues on Aging

...ey also plan to use the worms as modelorganisms to investigate how the drugs inhibit seizures in epilepticpatients, a mechanism that currently is not well understood. Suchresearch could lead to more effective treatments for epilepsy....

“Nano-scissors?laser shows precise surgical capability

...scle. Until now,researchers have only been able to investigate nerve regeneration inmice and zebrafish, which have complex nervous systems. This laserallows researchers to study nerve cells at their most basicevolutionary form, opening the door to other experiments on genetic andmolecular factors that determine ...

Researchers reveal the infectious impact of salmon farms on wild salmon

...mon," says Lewis. "The next step is to thoroughly investigate the degree of impact on wild populations," adds Krkosek. The authors concur that their findings point to a need to reconsider the premise of industrial scale fish farming in wild salmon habits. "There's a double bottom line here. The full ecological...

Mouse brain tumors mimic those in human genetic disorder

...lia."Next, the researchers used the mouse model to investigate a clinicalconcern. Physicians rely on several tests to determine whether a childwith an optic pathway glioma should undergo treatment for the tumor,including the tumor's size and the patient's clinical symptoms. Butoften those tests aren't sufficient...

Scientists decipher genome of fungus that can cause life-threatening infections

...a microarray and has formed aconsortium to further investigate the function of C. neoformans genes.The sequence data also provides the foundation for a broader genomeproject that aims to define the molecular basis for the C. neoformansspecies cluster, which includes three related yet diverged specieswhich differ...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...udies involved only single genes, but we wanted to investigate entire chromosomes, which contain hundreds of genes," Bernstein notes. He and Schreiber enlisted the help of Affymetrix, which makes so-called "gene chips" that rapidly scan millions of small sections of chromosomes to detect gene activity. But the ...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...elopment of thatbrain region, and which of them to investigate as possible causes ofbrain tumors and other diseas... brains of developing mice.Using genetic probes to investigate thin sections of mouse brains, thescientists found that only 349 of the TF genes were expressed insp...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

... go beyond looking at clathrin per se, and try and investigate other players in the endocytotic process," he said. ÒWe're going to ask questions such as, 'OK, if I tweak this molecule, how does that change clathrin's role in all of this?'Ó "It's really quite exciting," Dr. Ryan said. "This new methodology, coup...

Scientists develop new color-coded test for protein folding

...old nanoparticles have not been previously used to investigate the folding and unfolding of proteins." The initial batch of gold-cytochrome solution had a rosy red hue and a pH value of 10--about the same as an over-the-counter heartburn medication. But when drops of hydrochloric acid were added, the solution b...

Highly adaptable genome in gut bacterium key to intestinal health

... Next, the researchers will use germ-free mice to investigate how B. theta interacts with other members of the gut ecosystem. By defining the factors that underlie the stability of the gut ecosystem, they may be able to develop ways to manipulate the gut's bacterial community to promote health or treat diseases...

NIAID Initiates Trial of Experimental Avian Flu Vaccine

Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against H5N1 avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today. Sites in Rochester, NY, Baltimore and Los Angeles will enroll ...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

To investigate tumors, pathologists currently rely on labor-intensive microscopic examination, using century-old cell-staining methods that can take days to complete and may give false readings. A lightning-fast laser technique, led by Sandia National Laboratories...

Plants defy Mendel's inheritance laws, may prompt textbook changes

..., either normal or mutated, so the scientists must investigate which genes might affect this novel inheritance in both plants and animals. "There are probably a lot of other triggers yet to be discovered, and this mechanism for inheritance may require a different trigger to make it work in animals," he said. O...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...ted its similarity to TEL1, which prompted them to investigate whether TEL2 also played a role in leukemia. In the MCB study, the investigators discovered that, unlike TEL1, TEL2 promotes cell multiplication, playing an indirect role in the development of B lymphoma. "TEL2 doesn't directly cause cancer," Grosve...

Use of Insecticides Linked to Lasting Neurological Problems for Farmers

... The AHS (http://www.aghealth.org/) is designed to investigate the effects of environmental, occupational, dietary, and genetic factors on the health of the agricultural population. The study will provide information that agricultural workers can use in making decisions about their health and the health of their...

How the environment could be damaging men's reproductive health

...ved. "We need a much larger population in order to investigate the implications of these changes on sex ratio of offspring as the number of children born to these fishermen was small. "However, we think the fact that exposure to environmentally derived chemicals can change the sex chromosome ratio in sperm is w...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

...excess cancer risk in people infected with HIV and investigate the modifying effects of the use of HAART and behavioral factors on this cancer risk, Gary M. Clifford, Ph.D., of the International Agency for Research on Cancer in Lyon, France, and colleagues analyzed data from the Swiss HIV Cohort Study and Swiss ...

Decoding the logic of olfaction

...ented in this structure. They therefore decided to investigate the patterns of activity that were triggered by a range of odorants in the olfactory cortex of mice. "We wanted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a...

Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer

...ented in this structure. They therefore decided to investigate the patterns of activity that were triggered by a range of odorants in the olfactory cortex of mice. "We wanted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a...

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