Gene chip technology shows potential for identifying life-threatening blood infection
... the immune system's first line of defense against invading organisms. "At one level, we've found a suite o...ether gene chips can identify the specific type of invading organism in the blood samples. Early findings suggest that the technology detects differences in mol...Autoimmune disease triggered if T cells miss a single protein early on
...receptors to recognize the tremendous diversity of invading pathogens. In the process, however, they also develop receptors that bind to the body's own proteins. These T cells are normally eliminated, avoiding the plague of autoimmunity. A clue to how the elimination process is controlled came from previo...Proteins anchor memories in our brain
...receptors to recognize the tremendous diversity of invading pathogens. In the process, however, they also develop receptors that bind to the body's own proteins. These T cells are normally eliminated, avoiding the plague of autoimmunity. A clue to how the elimination process is controlled came from previo...Experimental vaccine protects mice against deadly 1918 flu virus
...lls critical in the immune system's battle against invading viruses, as well as the production of neutralizing antibodies. To determine the vaccine's protective effects, the CDC's Dr. Tumpey intranasally exposed a group of mice to live, reconstructed 1918 virus 14 days after they were immunized with the ex...HIV exploits competition among T-cells
... threat, mounts a defense and destroys most of the invading viruses. The second phase is a long period of clinical latency that can last up to 10 years. In this phase, a small amount of virus mutates fast enough to escape initial detection and continues to mutate over time. The third phase, AIDS, occurs when ...Edge density key to controlling gypsy moth spread
...he first identification of pulsed invasions for an invading species." Bjornstad; Derek M. Johnson, Departmen...urges of growth that expand the territory. Other invading species may also exhibit pulsed spreading. If researchers can determine that the Allee effect is in ...... APOBEC proteins produced by a host normally cause invading viruses to mutate so much that they can't survive, but HIV-1 uses a protein called Vif to destroy APOBEC and prevent the attack. Monkey APOBEC proteins, however, aren't susceptible to the human virus's Vif. So Hatziioannou did another swap -- the SIV...A key antibody, IgG, links cells' capture and disposal of germs
...G) helps bring together the phagosomes that corral invading pathogens and the potent lysosomes that eventually...the processes by which cells isolate and then kill invading microbes, viruses, and other antigens. In a process called phagocytosis, intruding germs are firs...Plants give up answers in the war on bacteria
...s the role of the plant's pores in defense against invading bacteria and how some bacteria can overpower plant...sis business and were merely unwitting doorways to invading bacteria on a plant's surface. Melotto and Underwood, however, have discovered that stomata are an i...Natural anti-viral enzyme helps keep cancer cells alive, researchers find
..., in which the body creates new antibodies against invading pathogens. A great deal is currently understood about how the adaptive immune system fights cancer and also helps create tissue environments permissive to cancer, Dr. White said, but a cancer-promoting role for the host defense response has not been ...Tiny Tampa Bay fish key to evolution of immune system
...ne response to recognize and counter components of invading microbes. If so, it would provide an illustration of the potential for studies of diverse species, even those that at first glance may appear to be of no special interest, to yield information of value in understanding human physiology and of use in ...'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines
...rred by the new flu infection ? means that the new invading influenza is effectively crowded out by the 'protecting virus'. This vastly slows the progress of the new infection, prevents flu symptoms, and gives the body time to develop an immune response to the harmful new invader. In effect the protecting v......nds the heart, called the epicardium, follow suit, invading the wounded cardiac tissue and stimulating the gro...those epicardial cells then alters their identity, invading the wound and providing essential new blood vessels to the growing muscle. They further found that...Cancer cells forming blood vessels send their copper to the edge
... in areas of tissue where blood vessels were newly invading surrounding tissue, the cells showed copper localized at the periphery of the cells and in areas immediately outside of any apparent cellular structures." What are the implications of this discovery? According to Finney, "These findings improve...Cracking open the black box of autoimmune disease
...the frontline soldiers of immune defense, engaging invading pathogens head on. These T cells are commanded by a second group of cells called regulatory T cells. Regulatory T cells prevent biological "friendly fire" by ensuring that the T cells do not attack the body's own tissues. Failure of the regulato...Antibody signal may redirect inflammation to fuel cancer
...ite blood cells, or leukocytes, engulf and destroy invading microbes when receptors on their surface receive a...w that inflammation, usually a helpful response to invading pathogens, can become misdirected and fuel cancer. The new research was presented today (Februar...RNAi shows promise in gene therapy, Stanford researcher says
...ular degeneration, or disables genes needed by an invading virus. With key genes shut off, viruses such as hepatitis or HIV are unable to multiply and cause disease. In early RNAi experiments, researchers saw some hints that the technique could induce an immune reaction or switch off the wrong gene or ...Researchers discover surprising drug that blocks malaria
...blood cells to engulf them -- and how to block the invading parasites. The malaria marauders hack into the red cell's signaling system and steal the molecular equivalent of its password to spring open the door to the cell. But researchers have found that a common blood pressure medication ?propranolol ?jams t...Inflammation may play role in metastasis of prostate cancer
... by the cancer cells. Instead, it is expressed by invading inflammatory cells. Interference with RANK ligand production or activation, as well as interference with IKKa activation, may offer new therapeutic strategies for prevention of metastatic disease.......ia," said Singh. "Because gallium looks like iron, invading bacteria are tricked, in a way, into taking it up. Unfortunately for the bacteria, gallium can't function like iron once it's inside bacterial cells." The researchers showed that gallium killed microbes, and prevented the formation of biofilms. ...