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Tag: "invade" at biology news

Dysentery uses 'sword and shield' to cause infection

...a, the bacteria which causes dysentery, is able to invade cells, while stopping any response from the immune system. They found that shigella was able to infect cells by using a secretion system to inject proteins into human cells, (the sword), while lipopolysaccharide (LPS) on the surface of the bacteria ...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

...the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec....umoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude ...

New comparative toxicogenomics database

...the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec....umoniae is the only bacterium known to use CbpA to invade humancells by binding to pIgR, according to Richard W. Kriwacki, Ph.D.,associate member of St. Jude ...

DNA Recombination and Repair—A New Twist to RecA Function

...NA helices lined with RecA protein. RecA filaments invade a region of double-stranded DNA with similar nucleotide sequence, displacing one strand to pair with the other. Strand invasion can lead to a re-assortment—known as recombination—of DNA regions on either side of the shared sequence. It can also initi...

New protein discovered by Hebrew University researchers

...herefore, the units of SP-1carrying the drug would invade only the tumor-feeding blood vessels andnot normal ones.More recently, the three-dimensional structure of the protein wasdeciphered by x-ray crystallography. The research on this was publishedin the Journal of Biological Chemistry issue of December 2...

The death of a very special chimpanzee

...herefore, the units of SP-1carrying the drug would invade only the tumor-feeding blood vessels andnot normal ones.More recently, the three-dimensional structure of the protein wasdeciphered by x-ray crystallography. The research on this was publishedin the Journal of Biological Chemistry issue of December 2...

Scientists discover that host cell lipids facilitate bacterial movement

... commandeers its host cell's actin cytoskeleton to invade other cells. In a report published in the Journal of Biological Chemistry, a group of scientists provide insight into the molecular mechanisms behind this infection technique. The research appears as the "Paper of the Week" in the March 25 issue of ...

Scientists solve structure of key protein in innate immune response

When bacteria invade the body, a molecule called CD14 binds to substances liberated from the bacteria and initiates the cellular defense mechanisms. In a report published in the Journal of Biological Chemistry, scientists in Korea announced their elucidation of three-dim...

World's largest rainforest drying experiment completes first phase

...his scenario nonetheless. What types of trees will invade the forest that has now been "released" from its imposed drought? And are the trees that survived somehow damaged, and unable to respond to this release? Have the vessels that conduct water from their roots to their leaves become clogged with water v...

Leprosy microbes lead scientists to immune discovery

...ody develops protective immunity against bugs that invade our cells--or fails to. Now we know the players, and we would love to look at them in other diseases such as tuberculosis in the lungs and juvenile diabetes." Harvard School of Public Health is dedicated to advancing the public's health through lear...

Used in a new way, RNA interference permanently silences key breast cancer gene

...atly reducing the ability of these cancer cells to invade normal tissues like the lung. "Somehow STAT3 is controlling TWIST expression, and this is important to know with regards to activated STAT3 and its involvement in cancer metastasis," Arlinghaus says. When the mouse breast cells transduced with STAT3...

Shutting down the HIV assembly line

...rst like bubbles out of the cell, and float off to invade other cellular factories. Vanderbilt University Medical Center investigators have now identified an early step in HIV particle assembly. The findings, published March 11 in Cell, could lead to new drugs that combat HIV infection by shutting down the ...

Active Vaccine Prevents Mice From Developing Prion Disease

...clumps. As an infection takes hold, prion proteins invade brain tissue and force normal proteins to adopt their configuration. In time, the diseased animal develops dementia, loses control of its limbs, and eventually dies. There are no treatments for prion-related diseases, and prions can easily infect th...

Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils

... was it carried over to land, or did each organism invade land and forge a new relationship independent of the marine relationship? If the latter, then the 600-million-year-old relationship may not be the direct ancestor of the 400-million-year-old relationship," Xiao said. Fungi and algae in modern lichen...

Malaria mechanism revealed

...ure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuab...nfection, merozoite-stage parasites ("merozoites") invade red blood cells, leading to clinical symptoms and in many cases, death. "Niraj Tolia [the first aut...

Immune system's distress signal tells bacteria when to strike back

...the weakened bowel wall, enter the bloodstream and invade tissue. "Our goal," Alverdy said, "is to understand the many steps in this process and use that knowledge to find novel ways to intervene, to stop the infection before it starts rather than trying to kill all the germs." Many harmful bacteria have ...

When it comes to cell entry, being average has its advantages

...ng. Yet scientists have shown that flu viruses can invade cells even without a clathrin coat. Along with Huajian Gao and Wendong Shi from Max Planck, Freund created a mathematical model that can account for this. Particle size plays a key role. According to the team's new model, cells take in viruses and ot...

Gene expands malaria's invasion options

... Plasmodium falciparum uses different pathways to invade red blood cells, evading the body's immune system ...s a year worldwide. Some P. falciparum strains invade red blood cells via protein receptors on the surface that contain a sugar known as sialic acid. If s...

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells

...lness, commandeers cellular transport machinery to invade cells and hide from the body's immune system. They...elieved a cell could take in by endocytosis ?could invade non-phagocytic cells. Other labs had made similar observations with other bacteria. Cossart and Veig...

Gene discovery sheds light on causes of rare disease, cancer

...lness, commandeers cellular transport machinery to invade cells and hide from the body's immune system. They...elieved a cell could take in by endocytosis ?could invade non-phagocytic cells. Other labs had made similar observations with other bacteria. Cossart and Veig...

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