High resolution 'snapshots' detail dynamics of a cocaine antibody
...talytic activity. Novel functional groups could be introduced into first generation antibody catalysts by multiple rounds of mutagenesis and selection to produce improvements. In essence, this would allow scientists to dramatically accelerate the evolutionary process, producing improvements in the immune system...Report finds cruise industry is protecting the precious places it visits
... in 2005. Between 2000 and 2004, 62 new ships were introduced to the North American market alone and another 20 are expected to come into service by 2009. Of the top 30 cruise destinations in the world, 20 are located in the Caribbean and Mediterranean, two important biodiversity hotspots. Among these, the 10 ...Study shows that cells have a natural defense against HIV
... DNA. Yoder, Fishel and their collaborators then introduced mutations into the genes for the two proteins, which crippled the proteins' ability to repair DNA. When cells with these mutations were then infected with HIV, they showed higher levels of provirus in their chromosomes. "When we weakened a DNA repa...... that boost the efficiency by which foreign DNA is introduced into this economically important crop." Herb S. Aldwinckle, professor in the Department of Plant Pathology at Cornell University, Geneva, New York, who has developed highly efficient techniques for transforming apple, remarked: "The commercial stra...Exotic crab poised for widespread UK invasion
...itoring and trapping system for the crab should be introduced before it is too late to control the population. Chinese mitten crabs are already present in some of our waterways, including the Thames, Humber and Tyne rivers and parts of the North Sea and Channel coasts. The study details how the UK colonis...Invasive exotic plants helped by natural enemies
... their natural enemies actually do better in their introduced ranges. The research from the Georgia Institute of...ic herbivores, including cattle, rabbits and goats introduced by Old World explorers, can encourage the spread of invasive exotic plants ?increasing their relativ...Scientists force viruses to evolve as better delivery vehicles for gene therapy
...ling the mutant viruses inside their capsids, they introduced them to blood serum pooled from rabbits immunized ...rs and subjected them to another round of PCR that introduced more mutations. After passing this second generation through serum three times, they isolated viruse...... that transport nutrients between ecosystems. "An introduced predator alters Aleutian island plant communities ...f birds nesting on the islands. Arctic foxes were introduced in the late 1800's to maintain the North Pacific fur trade, and later removed in an attempt to retur...Drug-resistant bacteria patterns in intensive care units changing nationally
...CDC epidemiologist Dr. Monina Klevens. "When it is introduced into a hospital, where ill patients are more vulnerable to infection, it has the potential to cause significant morbidity and mortality." Due to community MRSA's ability to infect the young and healthy, traditional risk factors for identifying hospi...Congenital rubella syndrome nearly eradicated in the US
...tal rubella syndrome, but a more effective vaccine introduced in the 1970s has helped in eliminating transmission of rubella from expectant mothers to their unborn babies. "Effectively, congenital rubella syndrome has been nearly eradicated from the United States," according to the statement. There were fewer...Nanopore method could revolutionize genome sequencing
...because the twisting and turning of the DNA strand introduced too much noise into the signal being recorded. The new idea takes advantage of the electric field that drives the current perpendicular to the DNA strand to reduce the structural fluctuations of DNA while it moves through the pore, thus minimizing t...'Prosthetic' retinal cells let blind mice see light
...that were not before. Using a harmless virus, they introduced a gene for a light-sensitive protein into "inner r...y School of Medicine and colleagues found that the introduced protein rendered the retinal neurons sensitive to light. What's more, they found, the protein persis...Study shows hope for ridding lakes of clawed invader
...s the promise of a rare victory in the war against introduced invasive species. Since 2001, the UW-Madison researchers, aided by a small army of undergraduate students and the Wisconsin Department of Natural Resources (DNR), has succeeded in significantly reducing the population of rusty crayfish in Sparkling...The loss of a protein favors lung tumor growth
...llular lines of different types of lung tumors and introduced a sequence of the protein αCP4 in order to observe the resulting effects. In some of the cells she demonstrated that the tumor proliferation was reduced. In particular, in malignant tumors of large cells she observed that their capacity for growth wa...Brittle prions are more infectious
...prion protein in three different conformations and introduced them into yeast cells. They then correlated the strength of infectivity of each prion with its physical properties and compared their results to those predicted by their mathematical model. According to Weissman, the researchers found that the slowe...Researchers map out networks that determine cell fate
...g different amounts of PU.1. When the researchers introduced low concentration of PU.1, they found that the cells activated both macrophage and neutrophil genes. "This showed for the first time how this mixed lineage pattern is set up," Singh said. When they increased the concentration of PU.1, however, the...Antarctic Treaty Meeting moves to protect frozen continent from non-native species
...t will reduce the risk of non-native species being introduced into both marine and terrestrial ecosystems in Antarctica. To protect the marine environment, the meeting adopted new practical guidelines for ballast water exchange by ships operating in the Southern Ocean around Antarctica. Under the new guideline...Iron critical to ocean productivity, carbon uptake
...have been involved in experiments in which iron is introduced into the ocean in an attempt to boost productivity. Those studies found that introducing iron into small portions of the Pacific did indeed trigger phytoplankton growth, but it wasn't as robust or as sustained as models predicted. "It wasn't the sil...Microscopic scaffolding offers a 'simple' solution to treating skin injuries
... patient's skin cells (obtained via a biopsy*) are introduced and attach themselves to the scaffold, multiplying until they eventually grow over it. When placed over the wound, the scaffold dissolves harmlessly over 6 to 8 weeks, leaving the patient's skin cells behind. This new approach to skin reconstructi...