Virulizin granted orphan drug status in Europe
...ween 1993 and 2003, fisheries in the United States introduced changes that reduced cetacean bycatch to one-third of its previous levels. But so far little of this success has been transferred to other countries, and in much of the rest of the world, progress on bycatch mitigation has been slow or nonexistent. ...Gaining ground in the race against antibiotic resistance
... evolve quickly to evade them. When the scientists introduced random mutations into the gene for a bacterial resistance enzyme and grew the bacteria on increasing concentrations of antibiotics, it took only a few days of test tube evolution to increase drug resistance. Eventually, they found four mutations in t...Results of world's first gene therapy trial for arthritis show approach safe, feasible
...itic knuckles and marked the first time a gene was introduced into a human joint. The researchers say their results showing that successful gene transfer can target joint inflammation open the door to the development of improved gene-based therapies for both rheumatoid and the more common osteoarthritis, which ...Infectious disease expert warns of spread of Rocky Mountain spotted fever
...es found naturally in the Arizona region, but were introduced to the state as domesticated dogs that moved with their owners into the area. "This study shows that Rocky Mountain spotted fever can show up in unexpected places, and the study should put physicians on alert for the earliest signs and symptoms of t...DDT-resistant insects have additional genetic advantage that helps resistance spread
...ncrease resistance to newer compounds subsequently introduced to try and overcome resistance. The World Health Organization estimates that during the period of DDT use, approximately 25 million human lives have been saved. Today pyrethroids are most commonly used in mosquito control but they act on the same ta...A New Era Of Hope For Neglected Diseases
After a barren period when very few therapies were introduced for neglected diseases, which kill around 3m people a year and cause the loss of the equivalent of 92m years' of healthy life, there are now over 60 drug research projects underway. In the PLoS Medicine analysis, which is based upon a 100-page repor...Study findings offer potential new targets for antibiotics
...ial targets for antibiotics ?the researchers first introduced a mutated copy of the ribosomal genes into E. coli cells and looked for those rare mutations that could interfere with cell growth. It was known from previous studies that such deleterious mutations occurred within critical regions of the ribosome. ...US/African project deciphers deadly parasite genome
...e. The disease became a major concern after it was introduced into South Africa in the late 1890s when infected cattle from northern Rhodesia (now Zambia) were imported to replace thousands of animals that had been killed during a devastating outbreak of rinderpest. Nobel Prize winning German microbiologist Ro...Emerald Spectre haunts Ontario's ash forests
...cessful eradication of a borer population that was introduced into Maryland and, subsequently, into Virginia in a shipment of infected nursery saplings from Michigan. Officials destroyed the saplings as well as all ash trees within a kilometre of each infected site. "The success in Maryland shows that if you g...Software 'agents' could help unmask reality of disease clusters
...ust be properly addressed. "Mechanisms need to be introduced that, for example, digitally sign and authenticate genuine agents and their transactions, and prevent 'Trojan horse'-like attacks by fake or rogue agents. "These mechanisms could include the creation of virtual institutions to insulate host organisa...Method slashes quantum dot costs by 80 percent
... more than $150 per liter. Later, other scientists introduced a new recipe by replacing TOPO with a mixture of ODE and oleic acid. Wong said the CBEN research team, which included CBEN Director Vicki Colvin, professor of chemistry, and Nikos Mantzaris, assistant professor of chemical and biomolecular engineeri...The right drug at the right time
... more than $150 per liter. Later, other scientists introduced a new recipe by replacing TOPO with a mixture of ODE and oleic acid. Wong said the CBEN research team, which included CBEN Director Vicki Colvin, professor of chemistry, and Nikos Mantzaris, assistant professor of chemical and biomolecular engineeri...Solexa and collaborating scientists illuminate the small RNA component of the transcriptome
...tion sequencing platform, which is scheduled to be introduced to the market by the end of this year. Using Solexa's unique high-throughput sequencing technology, the study identified over 77,000 unique small RNAs in Arabidopsis plants, 10 times more than previously known. This study, funded by the National Sci...Retinal scans eyed for New Mexico show cattle
...en the idea of mandatory cattle identification was introduced several years ago, cattle producers were concerned about expense, inconvenience and loss of privacy. But experts stress the importance of controlling cattle diseases before they get out of hand, said Clay Mathis, a livestock specialist with NMSU's ...Small molecule inhibitor of cholera discovered
...cholera bacteria from setting up an infection when introduced into the digestive tract of mice. Since most disease-causing organisms use elaborate virulence factors such as toxins to do their damage, the new approach should be widely applicable. "There is no reason our results cannot be replicated for a numbe...Sickle cell disease corrected in human models using stem cell-based gene therapy
...hat causes sickle cell disease, a viral vector was introduced in cell cultures of patients who have the disease....c gene was engineered into a lentiviral vector and introduced into hematopoietic stem cells. After the cells received the treatment, they made normal hemoglobin. ...Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
...irement for any gene therapy to be successful: the introduced gene must produce healthy dystrophin protein in la...y gene therapy studies did not look at whether the introduced dystrophin spread along the entire length of the muscle cell, which can be many millimeters long in ...Envisat radar surveillance protects endangered prehistoric fish
...al quota. In the last few years authorities have introduced measures to limit illegal fishing in the EEZ, defend France's economic interests, protect ecosystems and stamp French sovereignty on their territorial waters. A surveillance system using French naval vessels has achieved some success, however the num...Bugs expose underground carbon traffic system 10 times more important than fossil fuel burning
...hich would view the AM mycelia as food stuff, were introduced to half of the cores. After another four weeks the grassland was exposed to a particular form of carbon dioxide (a stable isotope of carbon, 13C) for 7 hours, a technique called pulse labelling. Concentration of 13C in cores was then analysed. The s...Olfactory system detects pheromones that control reproduction
...rabies virus for their studies because it could be introduced into a neuron and infect its way upstream along the network of axons that connect neurons. The virus could also jump the synapses between neurons, as it moved from one neuron to the next. As a result, the researchers could use the pseudorabies virus ...