Key mechanism in genetic inheritance during cell division identified
...gomerization process, ring assembly seems to be an intrinsic property of the Dam1 complex, as we have been able to induce self-assembly into rings in the absence of microtubules." The formation of rings around the microtubules by the purified Dam1 complex that the Berkeley collaborators observed has not been ...Two studies document rise of superbugs in the environment
...uthor of the Massachusetts study. The first is the intrinsic ability of bacteria to mutate and acquire resistance under antibiotic pressure. The second is the spread of MDR bacteria from patient to patient, often in hospitals or long-term care facilities like nursing homes. In the study, living in a long-term ...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...simple and amazing," Dai observes. "We're using an intrinsic property of nanotubes to develop a weapon that kills cancer." Trojan horse To assure that only diseased cells were destroyed in the experiment, the scientists had to find a way to selectively deliver carbon nanotubes into cancer cells and not into ...Researchers discover why melanoma is so malignant
...elanoma is so metastatic in part due to properties intrinsic to melanocytes themselves, and not simply because it is external and thus uniquely exposed to environmental stresses. For the second experiment, the team used microarray technology (chips covered with fragments of DNA that can measure gene levels...University of Delaware researchers develop cancer 'nanobomb'
...al energy imbalance to set off explosions that are intrinsic in nature. Panchapakesan said the nanobombs are just that, tiny bombs on the nanoscale. "They work almost like cluster bombs," he said. "Once they are exposed to light and the resulting heat, they start exploding one after another." The bombs a...Researchers quantify more noise in gene expression
... eliminate extrinsic variations," said Hasty. "And intrinsic and extrinsic variation in gene expression also pr...d an 'extrinsic-noise floor' in 11 genes for which intrinsic noise is negligible." The group measured the noise floor by used genetically engineered strains of...Phenotype is influenced by nature, nurture and noise
...puter model of cellular reactions, by factoring in intrinsic noise and delays. Using the modified Gillespie alg...ctions, the team discovered how the combination of intrinsic noise and biochemical delays also generates oscillations in phenotype. "We think an analysis of suc...A resetting signal keeps circadian rhythm on track in Drosophila fruit flies
... the evening clock every day, without changing the intrinsic speed of the evening clock. Between daily resets, therefore, the evening cells time evening activity with their own clock, but they will always start counting time from the moment they were reset by the morning cells. In other words, the evening clo...ASU researchers 'wire' DNA to identify mutations
... consuming." The team's breakthrough relies on an intrinsic physical property of DNA, conductivity, or how well the molecule can carry an electrical current. Depending on the experimental conditions, DNA has been previously shown to act as both a conductor and insulator. "We have developed a technology that...Superconducting magnet attracts molecular research
...rons, neutrons and protons within the atom have an intrinsic property known as "spin" and within the electromagnetic field created by the magnet, the frequency of the spinning motion of the atoms reveals information about the physical, chemical, structural and electronic characteristics of the molecule in solu...Researchers uncover mechanisms of estrogen in promoting cell death in breast cancer
...diol induces apoptosis by activating the so-called intrinsic apoptotic pathway. This pathway is controlled by proteins on the membrane of cell organelles called mitochondria. Estradiol increased the expression of several proteins on the membrane of cell mitochondria, led to depolarization of the mitochondrial ...Why the Amazon rainforest is so rich in species
...the evolution of species must largely be caused by intrinsic biological features of each group of species." He added: "This research is helping us understand the reasons behind the large number of species in the Amazon rainforest ?it's another piece of the biodiversity puzzle in place. Species split at very d...Sexual reproduction delays aging in a mammalian species
...that this pattern was not caused by differences in intrinsic biological quality, social rank, or workload between breeders and non-breeders. These findings provide unexpected new information for understanding the evolution of life histories, and they shed new light on the old question of the connection betwe...Natural selection at single gene demonstrated
...oS paper, along with other recent studies based on intrinsic genomic comparisons, brings biology closer to this goal. ...Unraveling the mysteries of poison
...proteins contain carbon and nitrogen atoms with an intrinsic magentic moment (spin) which strengthens the NMR's signals. Looking at spectroscopic data before and after the toxin affected the channel, it turned out that the poison attaches to a particular area of the channel ?the pore region ?and changes the ar...Measuring artery repair cells could become new heart disease test
...s --the disease progresses as the body's loses its intrinsic ability to repair and rejuvenate itself. Current methods for measuring EPCs ?which can represent as few as one out of 10,000 cells in a given blood sample ?are subjective and time-consuming, the researchers said. As an indicator of EPC cell levels, ...Evolution follows few of the possible paths to antibiotic resistance
...ght follow in driving from Boston to New York, one intrinsic property of DNA is that very many distinct mutational paths link any two variants of a gene," says lead author Daniel M. Weinreich, a research associate in Harvard's Department of Organismic and Evolutionary Biology. "Although this fact has been reco...Mutation in blood stem cells provides clues to cancer development
...roduction of red blood cells. As a result of this intrinsic defect, the bone marrow produces excessive numbers of red blood cells. "This discovery is important because if we can pinpoint an inhibitor that directly targets the JAK2 mutant allele, we can fight the disease without inhibiting normal stem cell di...UF scientists restore sight to chickens with blinding disease
... it. Scientists always doubt what they see -- it's intrinsic to how we operate. So I did this simple little test, drawing little dots on a piece of paper. The chick, which was standing on the table, came over to the paper and started pecking at all of them. It was so exciting." Later, more precise tests showe......response of neurons across the olfactory bulb with intrinsic signal imaging. The imaging technique maps brain activity by detecting changes in reflected light from the brain with a sensitive camera. To start, the researchers separated and identified the volatile compounds in each odor with gas chromatography....