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Influenza vaccine uses insect cells to speed development

... is punctured, and the influenza virus is injected into the fluid surrounding the embryo. The egg is then ...on of hemagglutinin from the virus and insert them into a baculovirus. Caterpillar cells are then infected with the virus and begin to produce the hemagglut...

RNA project to create language for scientists worldwide

Research into ribonucleic acids (RNA)--the building blocks of li..."will make it easier to turn molecular information into useful knowledge that can help us to understand how different cells grow and develop as they do. Thi...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...wasn't enough to turn these overactive lymphocytes into lymphoma cells. "The coup de grace consisted of a complete elimination of the apoptotic response through loss of p53 function," Grosveld said. "In fact, all TEL2/MYC B-cell lymphomas had lost their p53 function." Grosveld's team found that this seq...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...most functionally important proteins are assembled into machinery from one species to another is also, to a certain degree, conserved," said Ideker. "The circuitry is not exactly the same. In fact, there are striking differences that warrant more investigation." The team included Roded Sharan, a computer...

South America's vast pantanal wetland may become next everglades, UNU experts warn

...of active interest to U.S. scientists for insights into the lost biodiversity of Florida's famed Everglade...sformed millions of square kilometers of savannah, into open fields. Riparian forests along rivers have been cut down or degraded which has led to increased...

Falling ants glide back to trunk to avoid dangers of forest floor

...as up with this behavior and it was worth checking into a bit more." By painting the ants' rear legs with...looded as much as half the year, so an ant falling into the water will most likely end up as fish food. "That's what I think is the major evolutionary driv...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

.... The flight simulator, which fools a tethered fly into thinking it is flying freely through the air, is necessary to produce a stable pattern of wing motion and enabled the team to capture X-ray images at different stages of muscle contraction. By combining the technologies, the researchers could reconst...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...evelopmental events. They injected individual CNEs into embryos, along with a green fluorescent protein (GFP) reporter. By day two of development, 23 out of 25 CNEs injected had upregulated GFP expression, indicating interaction of these sequences with endogenous transcription factors. Different CNEs caus...

Scientists discover that host cell lipids facilitate bacterial movement

...l Chemistry, a group of scientists provide insight into the molecular mechanisms behind this infection tec...projections called filopodia. These filopodia push into adjacent cells and are ingested by them. The bacteria then enter the new cell and begin the cycle an...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...to people. The spectrometry measurements were fed into a computer database to create a computational model of the P. gingivalis proteome, resulting in a surprising find. “Some of the proteins we previously thought were important when they were expressed in the lab proved not to be when the organism is i...

UCSD team discovers specialized, rare heart stem cells in newborns

...Medicine. The cells are capable of differentiation into fully mature heart tissue. Called isl1+ cells, th...y also determined that the cells could be expanded into millions of progenitor cells by growing them on a layer of neighboring heart cells called fibroblast...

Scientists solve structure of key protein in innate immune response

...stal structure of CD14, providing crucial insights into how the receptor binds to its ligands. "Our structure shows that CD14 has a large hydrophobic pocket near its amino terminus," says Dr. Lee. "We propose that this pocket is the main binding site for LPS because previous biochemical studies demonstrat...

Love at first smell

...iment females were fooled by the protein fragments into believing that males with insufficient MHC molecul...nge of MHC molecules, females could also be fooled into believing that these males smelled repulsive: having too many immune genes for offspring. Dr Siân G...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

... Institutet announced today that they have entered into a strategic alliance designed to improve healthcar...lerating the translation of basic genetic research into tools for better diagnosis, prognosis, and treatment. During the next five years the projects inclu...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...erapeutic regimen, a radioactive antibody injected into the bloodstream that targets and kills cancer cells. Of the 76 patients enrolled in the study, 95 percent responded to the treatment and 75 percent had a complete response, meaning no evidence of cancer remained. More than three-quarters of patients ...

World's largest rainforest drying experiment completes first phase

... "This experiment provides researchers with a peek into the future of this majestic forest, a future that will most likely be drier because of global warming, El Niño episodes, and even the drying effects of rainforest clearing and burning itself." First, the biggest surprise noted thus far has been the ...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...lon. "Now, with our approach, we have put this job into the hands of the molecular biologist. Using off-th...ious and costly analysis. To trigger living cells into producing their own contrast agent, Ahrens gave them a gene that produces a form of ferritin, a prot...

Measuring the impact of post-genomics on Mediterranean populations

...es for generating new knowledge and translating it into applications that enhance human health? To achieve this, they continue, fundamental and applied research is needed and supported, stressing integrated, multidisciplinary and coordinated effort. The two-day workshop highlighted not only the impact of...

Scientists discover how fish evolved to float at different sea depths

...ations. These systems drive oxygen from the blood into the swimbladder allowing the fish to float at diff...res. My aim was to find out how these systems came into place and how this allowed for the great variety of fishes we have in our oceans today." The study ...

Gene therapy for Parkinson's disease moves forward in animals

...n its later stages. By inserting corrective genes into the brain, scientists studying small monkeys calle...tment involving the transplantation of fetal cells into the brains of Parkinson's patients, and his colleague Deniz Kirik, a neurobiologist. "This work wit...

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