Taking Aim With Nanoparticle PEBBLEs
...he targeted cell and shoot reactive oxygen species into it, setting off "an avalanche of damage," said Kopelman. By staying outside the cell, PEBBLEs avoid a problem that thwarts many chemotherapy drugs. "The really bad cancer cells get immune to chemotherapy drugs ?they pump the drugs back out," Kopelma...ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors
...ble, and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is that the pigment is found only in the bird's feathers and nowhere else in the body of the bird, indicating that parrots manu...Genetically modified natural killer immune cells attack, kill leukemia cells
...erent immune system cells. They placed this sample into a dish containing a type of human leukemia cell ca...fied. These modified NK cells will then be infused into the patient after the transplant in order to eliminate residual leukemic cells. In another applicati...UCSD researchers maintain stem cells without contaminated animal feeder layers
...eu5Gc. If these stem cells were to be transplanted into people, they would provoke an immune system attack eliminating their therapeutic value. While several laboratories have attempted to grow stem cells in alternative cultures, problems have remained. In some cases, human feeder layers were developed b...Transport System Smuggles Medicines Into Brain
...ble, and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is that the pigment is found only in the bird's feathers and nowhere else in the body of the bird, indicating that parrots manu...Scientists develop new color-coded test for protein folding
...erone isn't a protein, it's a steroid) --is folded into a unique, three-dimensional shape that allows it t...tion that some cytochrome c molecules had refolded into their original three-dimensional shape. In fact, the experiment showed that, when attached to gold f...Placenta Is A Rich Source Of Blood Stem Cells
... rise to a complete blood system when transplanted into an adult. Unlike other sites where blood stem cell... needle aspiration, a painful procedure, or coaxed into the blood and then collected. Both methods yield only a limited number of blood stem cells. For mor...Probing The Promise And Perils Of Nanoparticles
...olycationic polymers and similar nanoparticles get into cells involves a process called polycation-mediated endocytosis. But Hong's experiments suggest that nanoscale hole formation may be at least as important in allowing materials to travel through membranes. The work that Banaszak Holl, Hong and Lerou...Open microfluidic and nanofluidic systems
...edomâ€TM of contact angles at pinned contact lines into account. Such a contact line is visible in the upp...he surface channels and, in this way, moves deeper into the nanoregime. As one reaches a channel width of about 30 nanometer, one theoretically expects new ...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...cer, eventhough the tumors were implanted directly into mice. “This is an exciting strategy that seems to...eted viral genes and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When these non-propagating particles are inje...Highly adaptable genome in gut bacterium key to intestinal health
...adaptively shifts more than a quarter of its genes into high gear when its host's diet changes from sugar ...ls to break different types of carbohydrate chains into 'bite-sized' pieces; the utensils are a variety of enzymes directed at different types of carbohydra...Scientists identify genetic pathways essential to RNA interference
... through single-stranded messenger RNA and finally into proteins. Short, double-stranded pieces of RNA bin...nd his colleagues developed a strain of C. elegans into which they added a gene that caused the worms to glow under ultraviolet light but also turned that g...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...cer, eventhough the tumors were implanted directly into mice. “This is an exciting strategy that seems to...eted viral genes and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When these non-propagating particles are inje...Same mutation aided evolution in many fish species, Stanford study finds
... to shed their burdensome body armor and transform into a lighter, spryer fish. This is among the first ti...volved from a relatively uniform marine population into today's broad spectrum of shapes and sizes when the last Ice Age ended roughly 10,000 years ago. Bec......s of Crick, and his collaborator, James D. Watson, into the structure of DNA and into the genetic code made possible a new understanding of heredity at the molecular level. “Major curre...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
...ere self-sustaining populations of foxes persisted into the late 1990s). "When you go to an island that had foxes, it's very easy to walk around because the plants don't grow much higher than your ankles. But on the other islands, it's hard work just to get through the vegetation. It was exhausting just ...Gene Therapy For Parkinson's Disease Moves Forward In Animals
...n its later stages. By inserting corrective genes into the brain, scientists studying small monkeys calle...tment involving the transplantation of fetal cells into the brains of Parkinson's patients, and his colleague Deniz Kirik, a neurobiologist. “This work wit...Researchers trace evolution to relatively simple genetic changes
... dramatic change: a row of 35 armor plates turning into a small handful of plates - or even no plates at a...ng techniques to insert the armor-controlling gene into fish "that are normally missing their armor plates. And that puts the plates back on the sides of th...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
... dramatic change: a row of 35 armor plates turning into a small handful of plates - or even no plates at a...ng techniques to insert the armor-controlling gene into fish "that are normally missing their armor plates. And that puts the plates back on the sides of th...