Mouse brain tumors mimic those in human genetic disorder
...such brain images, physicians inject acontrast dye into a patient's bloodstream and look for accumulation ofdye around the tumor. Though dye accumulation may be a sign of tumorprogression, it is unclear whether that is always the case,particularly in optic pathway gliomas associated with NF1.Results from ...Spider Venom Could Yield Eco-Friendly Insecticides
...her paralyze insects or send their nervous systems into overdrive. King's NSF-funded research has provided...gy is to insert a gene for encoding a spider toxin into viruses that are specific to a particular insect genus, or even a small number of species within a g...Gene variations explain drug dose required to control seizures
...dings suggest that, by incorporating genetic tests into the prescription process, physicians might improve...dy is required before any such method could be put into practice, the researchers emphasized. In the March 28, 2005, early edition of Proceedings of the Na...Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
...me that converts glycogen, a stored form of sugar, into glucose, the body's primary energy source. As a re... investigators either injected the viral particles into the muscle or injected it intravenously in Pompe disease mice. Six weeks after muscular injection w...Enzyme shown to help protect genomic stability
...nent of which is cancer. For this reason, insights into the mechanisms of gene silencing could provide imp...osomes. Compact strings of nucleosomes, then, form into chromatin, the substructure of chromosomes. In many cases, when the DNA is tightly wrapped around th...Scientists decipher genome of fungus that can cause life-threatening infections
...t the data from the two strainsmay provide insight into what determines virulence," says BrendanLoftus, a ...ce will benefit a widerange of biomedical research into the increasingly significant humanpathogen. Stanford's Hyman says, "The two new Cryoptococcus genome...Needling Chromosomes Reveals Cell Division Secret
...large and intricate puzzle of how one cell divides into two -- aprocess fundamental to all organisms.In th... focus to determine wherethe needle is coming down into the cell. This is difficult with oneneedle, but with two it's a terrific challenge; and you really n...Poplar trees redirect resources in response to simulated attack
...olerance, for example by putting aside more carbon into storage so it will be available to help the plant ...plant's major resource. To see how it is allocated into various biochemical pathways is an incredibly powerful tool for learning how plants cope with stress...Purdue proves concept of using nano-materials for drug discovery
...round cells and regulate the movement of molecules into and out of the cells, contain a variety of proteins, some of which are directly responsible for cancer's ability to resist anti-tumor chemotherapy drugs. These proteins act as tiny pumps that quickly remove chemotherapy drugs from tumor cells, making...In the sea slug's defense against lobsters, confusion is key
...ug's ability to trick the lobster's nervous system into activating feeding-associated behaviors succeeds, in combination with ink and opaline's other effects, in distracting the lobster sufficiently to enable the slug's successful evasion. Because the set of behaviors stimulated by the slug's secretions ...Scientists discover the cellular roots of graying hair
...eted, they also progressively make errors, turning into fullycommitted pigment cells in the wrong place wi...treated early, but if the lesion penetrates deeply into the skin it isoften fatal. Sun exposure is a major risk factor in the disease, whichhas been increas...Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
...eted, they also progressively make errors, turning into fullycommitted pigment cells in the wrong place wi...treated early, but if the lesion penetrates deeply into the skin it isoften fatal. Sun exposure is a major risk factor in the disease, whichhas been increas...Essential mangrove forest threatened by cryptic ecological degradation
...logy of rivers has turned coastal mangrove lagoons into freshwater bodies. Such elucidation of past ecosystem processes and human-environment interactions is an essential part of the Past Global Changes (PAGES) project of the International Geosphere-Biosphere Programme (IGBP), funded by the U.S. and Swis......eted, they also progressively make errors, turning into fullycommitted pigment cells in the wrong place wi...treated early, but if the lesion penetrates deeply into the skin it isoften fatal. Sun exposure is a major risk factor in the disease, whichhas been increas...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
...ly of organs and tissues, like brains and muscles, into a complex living organism. HOX genes are also vital for understanding the way that people get certain cancers. "Many of the proteins that regulate these genes can suppress or enhance tumor growth," Bernstein notes. "Some of the genes can cause cance...New research questions basic tenet of neuron function
...ter neurotransmitters and release them when needed into the synapse, or space between nerve cells, where the chemical signal is transmitted to other neurons. It is known that synaptic vesicles release their neurotransmitters in two different "modes" ?one when the neuron is stimulated and actively relayin...Vital step in cellular migration described by UCSD medical researchers
...ectional movement of a cell provides a new insight into cell migration and ultimately could lead to therapeutic interventions in autoimmune diseases such as multiple sclerosis and Crohn's disease," said the paper's first author Naoyuki Nishiya, Ph.D., a postgraduate researcher in the lab of senior author ...U-M scientists find genes that control growth of common skin cancer
...ng BCC cellscould be reprogrammed to differentiate into various epithelial celltypes, ultimately capable of assembling fully-formed hair follicles.These results suggest that BCCs contain cells capable of multi-lineagedifferentiation, similar to normal hair follicle stem cells from whichthey may arise.If t...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
...a well-oiled machine. It may also give us insights into the kinds of disease states that can happen when c...ively small increase in clathrin kicks endocytosis into high gear." The study was conducted in fibroblasts, a kind of cell used in many cell-culture experi...New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
...thousands of regions of the genome are transcribed into overlapping RNA sequences and those sequences are .... Any single base in the genome can be transcribed into several different transcripts with different, but overlapping sequences. Often, transcripts from one...