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Tag: "intestinal" at biology news

Study identifies substances in grapefruit juice that interact dangerously with some drugs

...tering the body after they are consumed because an intestinal enzyme, CYP3A, partially destroys them as they are absorbed. Grapefruit juice, but not other commonly consumed fruit juices, inhibits this enzyme, allowing more of these drugs to enter the body. It was originally assumed that the ingredients respon...

OHSU study says stem cell 'fusion' occurs in tumors

...cells derived from adult bone marrow can fuse with intestinal stem cells of both normal and diseased tissue comprising the cellular lining of intestinal walls, known as the epithelium. The findings, reported recently in the Proceedings of the National A...

Transgenic goat's milk offers hope for tackling children's intestinal disease

...ial enzyme found in human breast milk, altered the intestinal bacteria in young goats and pigs that were fed the... lysozyme limits the growth of bacteria that cause intestinal infections and diarrhea, and encourages the growth of beneficial intestinal bacteria, lysozyme is co...

Gut microbes' partnership helps body extract energy from food, store it as fat

...which types of polysaccharides are most coveted by intestinal bacteria. Samuel colonized one group of gnotobiotic mice with the polysaccharide-digesting bacterium B. thetaiotaomicron. Another group was colonized with M. smithii, while a third group received both B. thetaiotaomicron and M. smithii. The arc...

New stem-cell findings can help the body to cure itself

... regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell. "This might eventually help us develop new drugs for things like neurological disorders and anaemia," says Professor Jonas Frisén. In most organs of t...

Researchers discover which organs in Antarctic fish produce antifreeze

...sorbed. In this case, AFGPs are secreted into the intestinal lumen where they protect the intestinal fluid from being frozen by ice crystals that come in with seawater and food. Internal fluids in noto...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

... This insidious, highly infectious disease is an intestinal illness that causes nausea, diarrhea, vomiting and stomach cramps. The research conducted at UH and BCM may save a number of people from a vacation nightmare through the creation of a quick, accurate test for the "Cruise Ship Virus." One of the dif...

New GI technologies improve internal organ visualization

...f this study as well as the close proximity of the intestinal wall to vasculature, an EUS-guided approach to per...ared the two procedures for accuracy in diagnosing intestinal bleeding. During a capsule endoscopy, the patient swallows a small camera that records images of ...

FSU biologists uncover mechanisms that shape cells for better or worse

...o interpret information from the sense organs, and intestinal cells are polarized to take up nutrients and move them into the bloodstream," he said. Poulton explained that in order to ensure cell polarity in the Drosophila oocyte, the cells surrounding it activate a classic signaling pathway known as the Epid...

BGSU biologist trying to crack microscopic code

...e Gulf of Mexico and Chesapeake Bay, and the human intestinal tract. That means the types of proteins in its outer membrane must change to reflect the environment, giving researchers a "thread you can pull," he says. Living in and adapting to different environments is "part of who they are," but also, Larsen ...

U of M researchers find immune-activating cells in intestines

...ota researchers have found a group of cells in the intestinal system of mice that are proven to turn on T-cells,...s are blind, and the body's immune response in the intestinal system would not engage to fight the infection," McSorley said. While the researchers used a mouse...

Radiation-killed bacteria vaccine induces broad immune response in mice

...d other diseases of public health concern, such as intestinal parasites. This strategy might also be deployed in the event of epidemic outbreaks or against bioterrorist attacks, says Dr. Raz. ...

Silence of the amoebae

...e which codes for a toxic protein that kills human intestinal cells infected with this devastating illness. Now ...d amoebae to serve as a live vaccine by evoking an intestinal immune response. If successful, it may put an end to amoebic diseases that claim the lives of thousa...

AIDS-related cognitive impairment exists in two separate forms

...first characterize the miRNA expression pattern in intestinal epithelium purified from normal colon tissue. This epithelial inner lining of the colon contains about 50 million test-tube shaped crypts that line the colon. Colon cancer arises in these crypts, and researchers believe that the cells of origin are ...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...first characterize the miRNA expression pattern in intestinal epithelium purified from normal colon tissue. This epithelial inner lining of the colon contains about 50 million test-tube shaped crypts that line the colon. Colon cancer arises in these crypts, and researchers believe that the cells of origin are ...

Protein found to control tumor growth in certain breast cancers

...otein, which is present in epithelial cells of the intestinal tract and lungs, is linked to the control of malignant cell growth. The study found that over-expression of the protein resulted in the nearly total inhibition of estrogen-dependent tumor growth in mice, and the reduction of estrogen-induced prolife...

New vaccine for condition that kills 500,000 children a year

...lace when the bowel folds in on itself, causing an intestinal blockage. Because the bowel obstruction was so rare, and the increased incidence was so small, the only way to evaluate the safety of a new rotavirus vaccine was to launch a clinical trial involving more than 60,000 infants. In 2000, Merck asked Ma...

Loosen leash on cancer protein 'watchdog,' researchers say

...n cells has the ability to halt the progression of intestinal tumors that arise from genetic predisposition. Whe...such a predisposition generally developed about 50 intestinal lesions within six months of birth, but mice modified for the study had only developed three or fewe...

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases

...amining mice infected with Trichuris, a species of intestinal parasites known as whipworms, the researchers were...ed type 2 T helper cells that fight infection with intestinal parasites like Trichuris, " said Colby Zaph, a co-author and Irvington Research Fellow at Penn. "In...

Gut protein found to protect against infection and intestinal breakdown

...stine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstru...tivate several genes that are known to protect the intestinal lining or attack bacteria. The research team also found that FXR molecules heavily lined the inside...

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