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Tag: "interplay" at biology news

Novel Enzyme Shows Potential As An Anti-HIV Target

... The regulation of HIV genes depends on a complex interplay between proviral DNA, cellular proteins and transcription factors, and Tat. Unlike most transcription factors, Tat activates transcription by binding to RNA, specifically to a bulging “stem-loop?structure that forms at one end of all viral transcript...

The very unexpected life and death of a leukemic cell

...early CLL is a disease in which there is a dynamic interplay between rates of cell division and cell death. The data could enable physicians to predict disease progression. ### In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells View the PDF of this articl...

NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses

...venting human colon cancer, they do illustrate the interplay between genes and common nutritional and medicinal agents in development of cancer in the intestines. The drug they tested, sulindac, was a highly effective chemoprevention agent, the researchers say, because it worked to induce expression of the p2...

Conserved amino acids play both structural and mechanistic roles in sandwich-like protein

...l and that it gives important new insight into the interplay between protein evolution, structure and folding." The researchers speculate that their conclusions about the azurin protein apply to most members of the sandwich-like protein family, but testing on other specific proteins must confirm that. "Bette...

Ancient immune defense mechanism is no match for HIV-1

...ess dsRNAs. "Our results suggest that the dynamic interplay between RNAi and SRS remains physiologically conserved from plants and invertebrates to higher vertebrate animals," explains Dr. Jeang. "Our finding that Tat is an SRS also helps explain the long-standing biological observation that when HIV-1 is eng...

Excess liver gene protects against high-fat diet

... and other problems of excess, suggesting that the interplay between genes and diet is important. "Now we have a vivid example of a specific genetic alteration with opposite effects in different nutritional environments." The researchers examined lipid metabolism and atherosclerosis in mice with an approxima...

Logging changed ecological balance for monkeys, damaged health

...nues the work at Illinois to better understand the interplay between habitat disturbance and primate conservations and health in Uganda. He is collaborating with veterinary pathobiologist Tony Goldberg and other researchers at Illinois, where state-of-the-art facilities and faculty expertise are uniquely suite...

Affymetrix and ParAllele Launch Industry's Most Comprehensive Product Line for Targeted Genotyping

...nues the work at Illinois to better understand the interplay between habitat disturbance and primate conservations and health in Uganda. He is collaborating with veterinary pathobiologist Tony Goldberg and other researchers at Illinois, where state-of-the-art facilities and faculty expertise are uniquely suite...

President Bush's cut to AIDS prevention in Africa would be devastating

...nues the work at Illinois to better understand the interplay between habitat disturbance and primate conservations and health in Uganda. He is collaborating with veterinary pathobiologist Tony Goldberg and other researchers at Illinois, where state-of-the-art facilities and faculty expertise are uniquely suite...

'Underground' tunnels discovered as means for communication between immune system cells

...licated. While it would be fascinating to see this interplay inside living tissue, detecting the tiny tubules in such a complex environment may be nearly impossible with current technology. ...

From a Few Wild Ancestors, a Citrus Cornucopia

... laboratories, citrus preserves allow the timeless interplay between citrus plants and their pesky pests and pathogens to carry on untouched—providing scientists with important glimpses into the plants?finely tuned, natural defenses. “But germplasm maintained in this manner is more vulnerable to natural disas...

NYU chemists use computer simulation to enhance understanding of DNA transcription

...nsed fiber as salt increases. This folding and the interplay between chromatin structures regulate fundamental gene expression. However, the molecular mechanism underlying this process remains unclear. The research team, which included NYU chemists Tamar Schlick, Jian Sun (now at the Cornell Medical School), ...

Hepatitis C complicated by morphine withdrawal

...use. Dr. Wen-Zhe Ho has been interested in such interplay for some time. His laboratory has previously shown using cell culture that morphine enhances virus replication and inhibits IFN-alpha (a natural anti-viral factor produced by immune, as well as host cells, and the only one approved in recombinant fo...

New study to explore cellular circuitry

...e cell's genes and their function, but also of the interplay between them. When complete, the diagram has the potential to reveal cellular approaches to treating many diseases, including cancer. The Frontiers in Integrative Biological Research (FIBR) Program at NSF supports research into central questions in ...

Past experience of pheromones induces dominant courtship behavior in fruit flies

By investigating the interplay between pheromone signaling and behavior in fruit flies, researchers have begun to understand how an adult fly's earlier experience as a young individual can influence its behavior towards other flies as an adult. In particular, the researchers found...

Islands in the Genome Promote Speciation

...aptation, and extinction are all controlled by the interplay between genetic and environmental factors. Understanding the genetic changes that lead to the formation of new species is an important area of research in evolutionary biology. In a new study, Thomas Turner, Matthew Hahn, and Sergey Nuzhdin worked w...

Adult stem cells aid recovery in animal model of cerebral palsy

...aptation, and extinction are all controlled by the interplay between genetic and environmental factors. Understanding the genetic changes that lead to the formation of new species is an important area of research in evolutionary biology. In a new study, Thomas Turner, Matthew Hahn, and Sergey Nuzhdin worked w...

Sahara's edge studied from ground, air and space to improve water management

...ds. "AquiferEx is a good example of the fruitful interplay between satellite remote sensing, air-borne campaigns and ground-truthing," added Saradeth. "It demonstrates the complementary nature of each and emphasises their individual importance. AquiferEx and Aquifer stand also for successful cooperation betw...

The brain is broadly wired for reproduction

...rs found neural circuits that coordinate a complex interplay between neurons that control reproduction and brain areas that carry the neural signals triggered by odorant molecules and those triggered by pheromones, chemical signals produced by animals. The researchers characterize their findings as an initial ...

Scientists directly view immune cells interacting to avert autoimmunity

...urs in vivo, she explained. "By understanding the interplay between pathogenic cells and protective cells, we hope to be able to refine the therapy to enhance its efficacy." The microscopy technique is a vital new tool, Tang said. "The function of the immune system involves multiple cell types interacting ...

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