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Tag: "internal" at biology news

U of MN researchers identify ataxia gene

...e effects of this abnormal protein, which provides internal structure to cells, will clarify how nerve cells die and may provide insight into other diseases, including amyotrophic lateral sclerosis (Lou Gehrig's disease) and Duchenne muscular dystrophy.The research will be published in the February print issu...

Predicting success

...may be exerting pressure to prevent this. When the internal pressure created by these fluids rises above a certain level, it acts as a barrier that keeps drugs and other materials from entering the tumor. The method the Institute scientists developed can measure, with a non-invasive MRI scan, whether the fl...

Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial

...n of Ebola, GP from the Sudan/Gulu strain, and the internal nucleoprotein (NP) from the Zaire strain. Subjects received three doses of vaccine or placebo at one-month intervals via intramuscular needleless injection. Three cohorts tested progressively higher doses of the vaccine at 2 mg (5 subjects), 4 mg (8 ...

Tiny polyps gorge themselves to survive coral bleaching

...owed that both Porites and Montipora used up their internal energy reserves. However, after a month of recover... only to survive and repair but also replenish its internal energy reserves. "We think that this means that coral like Montipora can switch how it gets its fo...

'Banana-jawed' fossil mammal linked to rare sound-producing skill

...side of its lower jaws. The feature is known as an internal mandibular fenestra. But knowledge essentially st...s of its jaws. "Paleontologists have known of the internal mandibular fenestra among fossil hyraxes since early last century, but its significance was poorly u...

Wisconsin scientists discover a master key to microbes' pathogenic lifestyles

...Bruce Klein, a UW-Madison professor of pediatrics, internal medicine and medical microbiology and immunology, and the senior author of the new study. "These microbes have to undergo an extreme makeover to survive in a host," says Klein, an authority on fungal diseases. "The million dollar question is was wha...

Embryos tell story of Earth's earliest animals

...sulfide. Such reducing substances slow or stop the internal degradation processes that occur very soon after cells die and also inhibit voracious bacteria. Hydrogen sulfide is known to have been present in the environment half a billion years ago, at the time of the animal kingdom's origin, and when the emb...

Depression model leaves mice with molecular scar

...npointed how social defeat changes the BDNF gene's internal machinery. They traced the gene expression changes to long-lasting modifications in histones, proteins that regulate the turning on-and-off of genes via a process called methylation. Methyl groups, the silencer molecules, attach themselves to the his...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

... flu shot, said Dr. Robert Munford, a professor of internal medicine and a collaborator on the study. Based on the protection they observed in the mice injected with ricin mixed with human-produced antibodies, the researchers projected that a RiVax-vaccinated human could withstand a lethal dose of injected ...

Stress substantially slows human body's ability to heal

...ffect on health." William Malarkey, professor of internal medicine; Stanley Lemeshow, dean of the School of Public Health and director of the Center for Biostatistics, and postdoctoral researchers Tim Loving and Jeff Stowell also worked on the research. ...

Travelers can avoid jet lag by resetting their body clocks

...hat results from a misalignment between a person's internal biological clock and the external social environment. Both bright light and melatonin have successfully been used in laboratory and field settings to "phase advance" (resetting the circadian clock earlier in time so that all the circadian rhythms of...

ASU researchers 'wire' DNA to identify mutations

...tip, a small current, or bias is used to probe the internal electronic states of DNA. By measuring the conductance, the team was able to understand the sequence information in the DNA and whether there was a mismatch in comparison to a normal DNA sequence. What they found was that just a single base pair mu...

Sleeping sickness parasite shows how cells divide their insides

...ght to light a mechanism that regulates the way an internal organelle, the Golgi apparatus, duplicates as cell...exceptionally streamlined and has only one of each internal organelle, making it ideal for studying processes of more complex organisms that have many copies in...

How E. coli bacterium generates simplicity from complexity

...tically be capable of generating a huge variety of internal states; however, researchers at UCSD will report in the Dec. 27 issue of Proceedings of the National Academy of Sciences (PNAS) that Escherichia coli doesn't gamble with its metabolism. In a surprise about E. coli that may offer clues about how hum...

MIT researcher presents new view of how the cortex forms

...n interwoven cascade of developmental events, some internal and some external, according to co-authors Mriganka Sur, Sherman Fairchild Professor of Neuroscience at the Picower Institute for Learning and Memory and the MIT Department of Brain and Cognitive Sciences, and John L. R. Rubenstein of UCSF. "Recent...

The brain is broadly wired for reproduction

...ion about the external environment, as well as the internal state of the animal." The studies also suggest that GnRH neurons influence a wide array of brain functions, possibly coordinating those functions with neuroendocrine status in order to optimize reproductive success, according to Buck. Almost all th...

Gene variation affects tamoxifen's benefit for breast cancer

...itself," says Rae, research assistant professor of internal medicine at the U-M Medical School. "Our study suggests that women who inherit a genetic variant in the CYP2D6 gene appear to be at higher risk of relapse when treated with five years of tamoxifen." Researchers at the U-M Comprehensive Cancer Center...

Limiting the damage in stroke

...d and dying brain cells are very actively using an internal "communications network" known as the NF-kB signalling pathway. Cells have many such networks; their function is usually to switch genes on or off, changing the chemistry and behavior of the cell. Most drugs work by interfering with molecules that pl...

How Fruitflies Know It's Time for Lunch

... system must coordinate a laundry list of signals: internal signals contain information about energy level, fo...hers inferred that hug levels do not solely signal internal energy requirements but respond to internal and external signals carrying information about the qual...

Older female fish prefer imperfect male mates, study finds

...ation would be that the visual system "develops an internal prototype of an object that is based on an average of all the male fish [the females] have seen," Morris said. "Therefore, any fish they see that is closest to this prototype is preferred." The same phenomenon has been suggested to explain attraction...

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