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Tag: "internal" at biology news

Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

...ich act as a signaling system that tunes the bodys internal clock. This signaling system helps to properly regulate daily rhythms of waking, sleeping, even hunger that is, if its formation has not been disrupted. This could explain why sound sleep doesnt come easily to kids whose signaling systems may no...

Cellular message movement captured on video

...protein filaments and tubes that comprise a cell’s internal cytoskeleton. While researchers showed that paxillin serves as a docking station for a variety of signaling and structural proteins, they have been limited to visualizing paxillin with dyes that stain cells rigidly attached to microscope slides. ...

Researchers discover inherited mutation for leukemia

...ary CLL," says coauthor John C. Byrd, professor of internal medicine and a CLL specialist. "They also show the importance of the gene in the pathogenesis of CLL, and direct us to target this gene with therapies that might re-activate it." The findings also provide evidence that some genes might contri...

U-M researchers discover gene switched off in cancer can be turned on

...David Reisman, M.D., Ph.D., assistant professor of internal medicine at the U-M Medical School. Results of the study appear in the advanced online publication of the journal Oncogene. The researchers sought to understand why BRM is not expressed in certain cancer cell lines. They found no mutations to t...

Penn researchers link cell's protein recycling systems

... appears this week in Nature. The cell has two internal pathways for breaking down proteins. The ubiquitin-proteasome pathway marks unwanted proteins with ubiquitin tags and shuttles them for rapid breakdown to a complicated structure called the proteasome. The second is the autophagy-lysosomal system, a ...

3-D ultrasound scanner provides in-depth view of the brain

...nd device designed for imaging the heart and other internal organs during endoscopic surgeries performed through tiny "keyhole" incisions about 3 centimeters in diameter (http://www.pratt.duke.edu/news/"id=417). To make the probe more suitable for brain scanning, the researchers shrunk it even further, to fit...

Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

...senior author of the paper, professor and chair of internal medicine at the University of Texas Medical Branch... The lead author of the paper, UTMB professor of internal medicine/endocrinology Larry Denner, said that by working with adult stem cells rather than embryoni...

Novel system developed to turn data into real-time, interactive 3-D images

... add and remove data, as well as to instantly view internal structures not otherwise visible. "Data viewing is rapid and allows accurate diagnosis in a fraction of the time that physicians must now spend using current image viewing technologies," Clements says. The technology can be applied to any la...

Keeping the immune system from starting a 'food fight'

... they showed that the visceral fat surrounding the internal organs of STAMP2-deficient mice became inflamed, and the animals developed spontaneous metabolic disease on a regular diet, manifesting insulin resistance, glucose intolerance, high blood sugar and lipid levels, and fatty liver disease. They also sho...

How to steer a moving cell

...rk of proteins called the cytoskeleton, the cell’s internal scaffolding, determines cell shape, helping the cell to grow and develop "growth cones." These are specialized structures at the tips of growing nerve fibers, called axons, which sense guidance signals in their environment and "steer" the axons. Ce...

Scientists develope a new model of artificial canine skin

...nsists of an external layer, the epidermis, and an internal layer, the dermis, separated by a basal membrane. A study of the interactions between the cell populations of the various layers is of vital importance for skin biology, but these interactions cannot be investigated adequately by means of conventiona...

Sleepless for science: Flies show link between sleep, immune system in Stanford study

...long as the sick ones. "We want to know how the internal clock knows the animal is infected, and how does the immune system know that you are not sleeping properly"" said Schneider. "How do those messages get sent back and forth"" Their findings also raise the question of why the flies have a change in ...

Rare soft-shell turtle, nesting ground found in Cambodia

...fused together to form a protective layer over the internal organs. To protect itself from predators, the turtle spends 95 percent of its life hidden in sand or mud with only its eyes and nose showing. It possesses long claws and can extend its neck with lightning speed to bite with jaws powerful enough to cr...

Left-right wiring determined by neural communication in the embryonic worm

...ear symmetrical at first glance, but we're full of internal lop-sidedness. From the hand used to pick up a pen... generated in the brain, to the orientation of our internal organs, humans are a glut of asymmetries. Worms aren't so different: The roundworm Caenorhabditis el...

Intelligent materials to regenerate bone tissue

... to the physiological and biological changes, both internal and external, of that system. Also necessary are size and shape characteristics, as well as mechanical functions appropriate to healthy bones. The specific tasks of the project focus on putting the finishing touches to the intelligent materi...

Natural antibiotics yield secrets to atom-level imaging technique

.... "Just as an MRI produces a detailed image of our internal organs, solid-state NMR spectroscopy is used to construct a detailed image of a peptide or protein and to reveal how it sits in the cell membrane," providing clues for modifications that might make synthetic AMPs even more effective in overcoming eve...

Sandia researchers take new approach to studying how cells respond to pathogens

... is in its second of three years of funding by the internal Laboratory Directed Research and Development (LDRD) program. Sandia is partnering on the project with the University of Texas Medical Branch (UTMB) at Galveston and the University of California, San Francisco (UCSF). Sandia is a National Nuclear S...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...tein on the surface of HIV, while the other was an internal protein from simian immunodeficiency virus (SIV). They used the latter because HIV does not cause disease in monkeys. The idea was that such rabies?vehicles, or "vectors," would help attract a strong response from the animal’s immune system, thou...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...g in patients," said Sally DeNardo, a professor of internal medicine and radiology at UC Davis and lead author of the study. Many researchers have studied heat as a potential treatment for cancer, but the difficulty of confining heat within the tumor and predicting an effective heat dose has limited its us...

Researchers identify ovarian cancer biomarkers

...d Buckanovich, M.D., Ph.D., assistant professor of internal medicine and obstetrics and gynecology at the University of Michigan Medical School. Buckanovich was at the University of Pennsylvania when he conducted this research. The study analyzed the largest number of samples to date in tumor vasculature, ...

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