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Tag: "interferes" at biology news

Bone Density Recovers After Teens Stop Injected Contraceptive

...U.S. women overall. Researchers believe that DMPA interferes with bone mineral density by lowering levels of estrogen, a hormone that promotes bone mineral density in women. The findings appear in the February Archives of Pediatrics and Adolescent Medicine. The study was conducted by Delia Scholes, Ph.D., of ...

New understanding of DNA repair may pave way to cancer treatments

...tly, his laboratory developed a small peptide that interferes with ATF2 function, efficiently blocking melanoma growth in mouse models. Ongoing studies are devoted to screening for compounds that mimic the peptide's actions and to allow for further development of the peptide toward clinical assessment. "Until ...

U of T researchers map role of Epstein-Barr virus in cancer

...of Molecular Cell. "This research shows how EBNA1 interferes with natural cell growth regulation by binding to ...BNA1 is introduced to cells, however, this protein interferes with natural cell regulation by binding to USP7 and preventing its interaction with the p53 protein....

Achilles heel of the herpes virus possibly found

...ooks like a functional region of B5 and apparently interferes with virus engaging of the cell receptor. The papers detail how the team isolated and characterized the gene that encodes B5, called hfl-B5, and used the DNA sequence to find out more about the protein structure of the B5 receptor. In the presentati...

Retroviral resistance gene found

...leus. "We suspect that the overexpression of FEZ1 interferes with intracellular trafficking of the viral preintegration complex and traps the viral DNA in the cytoplasm. We hope that learning more about this transport machinery might reveal a new target for antiviral drugs in the treatment of HIV-1 disease." ...

Bacteria are key to 'green' plastics, drugs

...four genes, each of which codes for a protein that interferes with or limits E. coli's ability to turn glucose into succinate. Bennett and San activated a second pathway and stimulated production by adding genes from lactococcus bacteria and sorghum. Each genetic pathway metabolizes glucose and produces succin...

Overbearing colored light may reveal a second mechanism by which birds interpret magnetic signals

.... The new findings show that bright-colored light interferes with magnetoreception such that migratory birds can no longer obtain the information required to head into their migratory direction. The findings point to the existence of two distinct mechanisms of magnetoreceptors in the birds--an inclination comp...

Carnegie Mellon University research reveals how cells process large genes

...rotein or, worse, produce an abnormal protein that interferes with normal cell behavior. But just how a cell's molecular machinery eliminates long introns without making errors has puzzled scientists for years. Now, investigators at Carnegie Mellon University have discovered that a novel mechanism, called rec...

Reversal of role for a viral protein associated with the development of lymphoma

...rotein or, worse, produce an abnormal protein that interferes with normal cell behavior. But just how a cell's molecular machinery eliminates long introns without making errors has puzzled scientists for years. Now, investigators at Carnegie Mellon University have discovered that a novel mechanism, called rec...

Once given 'no respect,' cells' tiny RNAS take driver's seat

...NAs of the right sequence, which at the very least interferes with their ability to be read to make proteins and sometimes leads to the RNAs' destruction. "Now we're figuring out the functions of these Myc-controlled microRNAs, other genes they regulate, and how else they might be involved in Myc-mediated init...

Global warming increases oyster sensitivity to pollution

...h levels are reported in seals. In humans, cadmium interferes with calcium metabolism and deposition in the bone. Accumulation over time can cause serious illnesses such as itai itai disease. Future research will focus on to what extent cadmium reduces thermal tolerance of cold-blooded species. ...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...doses, because the same drug that blocks pain also interferes with brain activity, leaving people drowsy and unable to think clearly. “What we need is a way to release GABA in the spinal cord where it can selectively block incoming pain signals from peripheral nerves,?says Fink. “If we can block transmission o...

How HIV disables the cells' call for help

...ow a part of a protein on the virus' outer surface interferes with the cells' normal immune response. But their work may have wider implications: this molecular fragment, which has such a devastating effect in one disease, might turn out to be an effective treatment for other disorders such as rheumatoid arthri...

Scientists use gene transfer technology and common virus to block neuropathic pain

...doses, because the same drug that blocks pain also interferes with brain activity, leaving people drowsy and unable to think clearly. "What we need is a way to release GABA in the spinal cord where it can selectively block incoming pain signals from peripheral nerves," says Fink. "If we can block transmission ...

Old drug shows new promise for Huntington's Disease

...initial indications that Clioquinol preferentially interferes with synthesis of the toxic form of the protein. "... mice and humans. Apparently through chelation, it interferes with the creation of beta-amyloid plaque in the brain, which has been implicated in the progression ...

Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases

..."We believe that interfering with the Rab9 pathway interferes with the ability of the viruses to exit the cell, thereby dramatically decreasing the ability of the virus to spread rapidly and produce infection," Hodge said. Because these viruses depend heavily on this exit pathway, they probably would not be ab...

Sickle cell disease corrected in human models using stem cell-based gene therapy

.... The aggregation of hemoglobin S inside red cells interferes with the body's blood cells' ability to flow through small blood vessels, depriving tissues of adequate oxygen supply. This can cause pain, anemia, infections, organ damage, and stroke. Approximately 80,000 people in the United States have this inher...

Spousal illness can trigger partner death

...armful to partners than others. The more a disease interferes with a spouse's physical or mental ability, and the more burdensome it is, the worse for the health of the partner. The study also found that specific illnesses impacted the spouse differently. For instance, among men with hospitalized wives, if the...

MIT research holds promise for Huntington's treatment

...ard Medical School have identified a compound that interferes with the pathogenic effects of Huntington's disease, a discovery that could lead to development of a new treatment for the disease. There is no cure for Huntington's, a neurodegenerative disorder that now afflicts 30,000 Americans, with another 150,...

UCLA paper examines how one disease may prevent another

...stive disease that damages the small intestine and interferes with absorption of nutrients from food, thrived on their "non-bread" diet. Wheat was discovered to be the culprit. Other diseases that benefit from severe caloric or protein restriction include kidney failure, type-II diabetes, inflammatory bowel dis...

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