Proteins anchor memories in our brain
... The scientists hope that better understanding of interactions in the thymus can lead to earlier, more effective treatment of autoimmune diseases. "When we see autoimmune disease in the clinic, we are usually looking at it in a relatively late stage. Tissue is already damaged, antigen expression is ramped up a...Autoimmune disease triggered if T cells miss a single protein early on
... The scientists hope that better understanding of interactions in the thymus can lead to earlier, more effective treatment of autoimmune diseases. "When we see autoimmune disease in the clinic, we are usually looking at it in a relatively late stage. Tissue is already damaged, antigen expression is ramped up a...'Killer' B cells demonstrate evolutionary link between fish and mammal immune systems
...alized few cells identified apart from the complex interactions that drive other white blood cells. Sunyer and his colleagues discovered this previously unsuspected B cell activity while examining the immune cells of rainbow trout and catfish. The researchers determined that these attack B cells account for mor...Complexity constrains evolution of human brain genes
...s attribute the slowdown to mounting complexity of interactions within the brain. "We know that proteins with more...slowly," Wu said. "Mutations that disrupt existing interactions aren't tolerated." Although the gene sequences from human and chimpanzee remain very similar, pre...Parental genes do what's best for baby
... “But we have shown that selection for positive interactions between mothers and their offspring, rather than conflict, can produce the sorts of imprinting patterns we see for a lot of genes. “For example, during placental development the maternal and offspring genomes have to work together to produce a fun...Finding the right mix: A biomaterial blend library
...iversity have developed new methods to analyze the interactions between cells and biomaterials. Their work could lead to inexpensive techniques for building better biomaterials. Polymers derived from the amino acid tyrosine make up a broad class of degradable biomaterials under investigation. Such materials pr...Mutant mice show key autism traits
... have developed a mouse that shows abnormal social interactions and brain hypertrophy characteristic of the diseas... showed major abnormalities in a variety of social interactions normally undertaken in mice, found the researchers. For example, they were far less likely to approa......to translate its material science expertise on the interactions between media and cells based on our long-standing leadership in blood filtration to develop this new approach to cell harvesting." The Pall system can be used to harvest cells from a broad range of biological samples including peripheral blood, bon...New technology enables faster, more efficient cell harvest: Cell therapy meeting study
...to translate its material science expertise on the interactions between media and cells based on our long-standing leadership in blood filtration to develop this new approach to cell harvesting." The Pall system can be used to harvest cells from a broad range of biological samples including peripheral blood, bon...Researchers discover how bacteria sense their environments
... and a novel spectroscopic technique for measuring interactions between them, Crane's group was able to develop a model for how the complex of receptors is organized. Jack Freed, Cornell professor of chemistry and chemical biology and director of the National Biomedical Center for Advanced ESR Studies at Cornell,...New study reveals structure of E. coli multidrug transporter protein
... This binding is likely facilitated by hydrophobic interactions within the internal cavity of EmrD. The researchers speculate that cyanide m-chlorophenyl hydrazone is either expelled from the bacterial cell or into the periplasmic space-the space between the outer membrane and the plasma membrane in gram-negative...No-mow grass may be coming to your yard soon
...gh cell surface receptors to regulate cell-to-cell interactions and many of the events of embryogenesis in metazoans. "Because one of the brassinosteroid signaling components was similar to a protein found in the Wnt signaling pathway, we thought that the logic for brassinosteroid signaling (in plants) would be...Fly's courtship sheds light on the formation of innate behaviors
...s the gene itself is affected by external cues, by interactions with other genes, and by the organism's neuronal environments. ...Study identifies substances in grapefruit juice that interact dangerously with some drugs
...grapefruit juice that causes potentially dangerous interactions with certain medications. For almost a decade, pe... assumed that the ingredients responsible for drug interactions were the flavonoids that give grapefruit juice its bitter taste. The new study shows that a group ...Report warns about carbon dioxide threats to marine life
...ut we are only beginning to understand the complex interactions between large-scale chemistry changes and marine ecology. It is vital to develop research strategies to better understand the long-term vulnerabilities of sensitive marine organisms to these changes." The report, "Impacts of Ocean Acidification on C...Variations in detoxifying genes linked to Lou Gehrig's disease
...y, open the door to investigating gene-environment interactions as a cause of ALS and other illnesses and to the development of molecular targets for specific treatments. The study was published in the August 22 online issue (available now) of the journal Neurology. Siddique is Les Turner ALS Foundation/Herbert...Links between DNA damage and breast cancer studied
...escribed may potentially disrupt normal reciprocal interactions between the cell types, thus increasing breast cancer risk." The findings suggest that lesions measured in the DNA of the stroma, which is readily obtained, may prove to be convenient and sensitive biomarkers for assessing oxidative DNA damage and fo...The brain, traffic and nano-circuits -- e-Science takes on major challenges
...n individual neurons (brain or nerve cells) or the interactions between networks of neurons that lead to thoughts and behaviour. The techniques are time-consuming, difficult and expensive, but researchers rarely record their data or models so that they can be used by other labs or research groups. CARMEN will hel...Speeding the search for elusive chromosomal errors
...lar disease, a complex disorder thought to involve interactions among multiple genes. Dr. Shaikh is currently collaborating with other researchers at Children's Hospital to evaluate other, higher-density gene chips (holding more than 500,000 oligonucleotides), which provide greater resolution. His team is also d...Gut microbes' partnership helps body extract energy from food, store it as fat
Researchers studying mutually beneficial interactions between members of our vast community of friendly ...h other and their hosts. Gordon's lab models the interactions between friendly gut microbes and their hosts using gnotobiotic mice. These mice are raised in a man...