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Tag: "interaction" at biology news

In a technical tour de force, Salk scientists take a global view of the epigenome

...A. Adding a bulky methyl group to a C often blocks interaction with proteins required to activate gene expression, effectively silencing the methylated gene. Ecker and Jacobsen were funded by the National Human Genome Research Institute (NHGRI), which launched a public consortium known as ENCODE, for the Ency...

Speeding discovery of the 'human cancer genome'

...sis gene." Nedd9's role appears to result from its interaction with another enzyme known to be important for cell's ability to migrate and take root. As further evidence, they also found that the Nedd9 gene was frequently expressed at higher levels in metastatic human melanomas compared to primary melanomas. ...

A catalogue of proteins

...t allows a new understanding of their function and interaction with other cellular proteins and cell organelles." The researchers hope that protein correlation profiling will allow them to determine which proteins participate in failures of regulation. This could contribute to research into diseases which occur ...

Mosquito spray increases toxicity of pyrethroids in creek, study finds

...xicity was relatively modest, the effects from the interaction of chemicals were unexpected, the researchers said...rative biology and lead author of the study. "This interaction of compounds is a whole new issue when doing pesticide risk assessments that has been largely ignore...

Study finds how organs monitor themselves during early development

...ticular signaling pathways. They looked at how the interaction between the two types of cells in the ovary plays out. "Somatic cells and primordial germ cells develop in close contact with each other," says Dr. Gilboa. "Different cell types speak to each other, control each other and function together when an or...

DOE JGI sequences, releases genome of symbiotic tree fungus

...on and carbon management, particularly through the interaction with the poplar tree, also sequenced by DOE JGI," Rubin said. "We can now harness the interaction between these species and identify the factors involved in biomass production by characterizing the ...

UCLA scientists strengthen case for life more than 3.8 billion years ago

...e debate, including the chemistry of water and the interaction of water and rock. "The chemical evidence for life has been challenged, as have been the minerals to determine whether life was present, whether the rocks have the origin that was originally attributed to them, and whether the rocks were as old as or...

Rice scientists unveil 'nanoegg'

...irect result of our increased understanding of the interaction between light and matter in this critical size regime." Like nanoshells, nanoeggs have a spherical, non-conducting core that's covered with a thin metal shell. But where the casing on a nanoshell has a uniform thickness ?like the peel covering an o...

Study reveals details of mussels' tenacious bonds

... force microscope tip and measured the strength of interaction between DOPA and inorganic and organic surfaces. They found that on an inorganic metal oxide surface DOPA interacts with the substrate by a coordinated noncovalent interaction, which is over an order of magnitude stronger than hydrogen bonding but ...

Heal thyself: Systems biology model reveals how cells avoid becoming cancerous

...thin a city. The team discovered that part of the interaction network was involved, as expected, in repairing damaged DNA. However, they were surprised to find that a much larger part of the network is involved in modulating the expression of genes not directly related to DNA repair, such as genes involved in c...

A protein complex that untangles DNA

...lex appears to resolve these intertwines by direct interaction with the DNA molecules, but this process is differently regulated as compared to the function in repair. "Evidence points to that the Smc5/6 complex work in two different pathways, one needed for repair and the other for untangling. We now aim to ...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

... In his most recent study, Gourse investigated the interaction between RNA polymerase and promoters from the E. coli chromosome. RNA polymerase reads the information in DNA and transcribes it into chains of RNA, which are later translated into proteins. Promoter regions are specific sequences within the DNA chai...

Promising cell protein may play role in infection and dry eye

..., published their study, "Cytoplasmic and nuclear interaction between Rb family proteins and PAI-2: a physiolog...mple researchers demonstrate for the first time an interaction between PAI-2 and the tumor suppressing gene Rb2/p130 in the nucleus of the epithelial cells in the ...

Plant protection from cold decoded

...d protection proteins, according to the paper. The interaction worked both in the test tube and in the live plant. "The better we understand this molecular mechanism, the better we can control the process of increasing the plant's freezing tolerance without causing negative impacts," Zhu said. "This process sho...

Making a face: A new and earlier marker of neural crest development

...ent than previously thought, and is independent of interaction with other forming tissues, according to a recent ...cells and their derivative cell types, without any interaction with neural or mesodermal tissues. "Our results are contrary to current text-book models and sugg...

UCSD researchers develop 'smart petri dish'

...dividually. This is known as an adverse drug-drug interaction and it is very expensive and time-consuming to screen a new drug candidate with all the possible combinations of drugs that a patient may be taking. The Smart Petri Dish allows us to perform a large number of such toxicity assays simultaneously, in ...

Meth promotes spread of virus in HIV-infected users

...ptor by blocking it, we may be able to prevent the interaction of meth with its specific receptors, thereby inhibiting the virus attachment receptor," said Nair. "Right now, we don't know how the virus-attachment receptor and meth-specific receptors interact with each other, leading to the progression of H...

Report focuses on the role good microbes play in future medicine

...ing committee. Another example of microbe-microbe interaction in probiotics is a phenomenon known as "competitive exclusion" in which beneficial microbes directly compete with disease-causing microbes for food and other resources, eventually crowding them out. One potential application of competitive exclusion...

Variations in detoxifying genes linked to Lou Gehrig's disease

...uster, and replication, gene expression, gene-gene interaction and PON serum/enzymatic studies may help elucidate the complexity of PON cluster association with ALS," Siddique said. Siddique hopes to study DNA samples from Gulf War veterans with increased incidence of sporadic ALS and has applied for their DN...

Report warns about carbon dioxide threats to marine life

...aline, and they are expected to remain so, but the interaction with carbon dioxide is making them less alkaline and more acidic. The increased acidity lowers the concentration of carbonate ion, a building block of the calcium carbonate that many marine organisms use to grow their skeletons and create coral reef ...

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